Compound Summary
Compound Information
药名: | codeine |
别名: | Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-; HSDB 3043; O(3)-methylmorphine; Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-; 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol; C06174; l-Codeine; CCRIS 7555; Morphine monomethyl ether; C1653_SIGMA; Methylmorphine; Codeine; CHEBI:16714; 3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6alpha-ol; (5alpha,6alpha)-17-methyl-3-(methyloxy)-7,8-didehydro-4,5-epoxymorphinan-6-ol; Morphinan-6alpha-ol, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methyl- (8CI); Coducept; Norcodeine, N-methyl; 76-57-3; Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5-alpha,6-alpha)- (9CI); Codicept; Morphine-3-methyl ester; Codeine anhydrous; O3-Methylmorphine; EINECS 200-969-1; Morphine 3-methyl ether; Norcodine, N-methyl; Codein; Morphine-3-methyl ether; STOCK1N-42851; (-)-Codeine; Codeine solution; BB_NC-0138; Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)- (9CI); 7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol; C5901_SIGMA; Morphinan-6alpha-ol, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methyl- |
分子式: | C18H21NO3 |
Smiles: | CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C=C4)O |
成分: | HBIN021216 |
OB_score: | 45.478905 |
CAS_id: | 76-57-3 |
SymMap_id: | SMIT00258 |
TCMID_id: | 3885 |
TCMSP_id: | MOL006982 |
PubChem_id: | 5284371 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE001563 | 罂粟嫩苗 | |||||
| TCMBANKHE002713 | 白罂粟 | |||||
| TCMBANKHE003990 | Folium Llicis Chinensis | 四季青 | To clearheat and toxic materials./Angina pectoris, coronary heart disease, thrombophlebitis, thromboangiitis obliterans (Buerger’s disease), lung heat cough, swelling pain in throat, dysentery, diarrhea, infection of biliary tract , urinary tract infection, burns and scalds, heat toxin swollen welling abscess, ulcer of lower limb, eczema, frostbite, cracking, wound, bleeding due to external injury. | |||
| TCMBANKHE004306 | Papaver bracteatum | 大红罂粟 | ||||
| TCMBANKHE004577 | pericarpium papaveris | 罂粟壳 | 1. Astringe the intestine, relieve diarrhea and alleviate pain. 2. Astringe the lung and relieve cough./Enduring cough, chronic diarrhea, prolapse of rectum, pain in stomach duct and abdomen. | |||
| TCMBANKHE007520 | Fructus Amomi | 砂仁 | To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy. | |||
| TCMBANKHE005699 | Rhizoma Corydalis | 廷胡索;廷胡;玄胡;元胡;元胡索;玄胡素 | For stagnation of vital energy or blood stasis resulting in headache, chest pain, hypochondriac pain, epigastric pain, abdominal pain, backache, arthralgia, dysmenorrhea or trauma. Recently, alos used for angina pectoris, peptic ulcer and neuralgia./1. Its components d-corydaline and d1-tetrahydropalmatine are analgesics.2. Decreasing the secretion of gastric juice and the amount of pepsin. | |||
| TCMBANKHE006371 | 白屈菜 | Pain in sensory nerve endings, pain from ulcer in digestive tract, stomachache, abdominal pain, enteritis, dysentery, chronic bronchitis, pertussis, cough, jaundice, edema, ascites, scab and lichen with swelling of sores, snake or insect bites. | ||||
| TCMBANKHE007928 | 白药子 | Septicemia, acute hepatitis, bacillary dysentery, parotitis, neurodermatitis, swelling pain in throat, heat toxin swollen welling abscess, wind-damp impediment pain, abdominal pain and diarrhea, blood ejection, bleeding, spontaneous external bleeding, bleeding due to external injury. | ||||
| TCMBANKHE006850/YEM-509 | Papaver somniferum|Papaver somniferum L. | 罂粟 | 罂粟 | 云南民族药物志：第三卷 | To fortify spleen and promote digestion, clear heat and disinhibit urine./Stomach reflux, abdominal pain, diarrhea, prolapse of rectum. | 傣族/基诺族/佤族/彝族 |
| TCMBANKHE006476/YEM-509 | Papaver somniferum|Papaver somniferum L. | 鸦片|罂粟 | 罂粟 | 云南民族药物志：第三卷 | To relieve pain, astringe intestines, suppress cough./Pain in heart and abdomen, chronic diarrhea, chronic dysentery, dry cough without phlegm. | 傣族/基诺族/佤族/彝族 |
| TCMBANKHE004691/YEM-353/YEM-961 | Fructus Amomi|Amomum villosum Lour. | 缩砂仁; 砂仁|阳春砂 | 阳春砂仁 | 云南民族药物志：第五卷 | Treatment of accumulation of damp in the spleen and the stomach marked by epigastric stuffieness and anorexia, vomiting and diarrhea in deficiency cold syndrome of the spleen and the stomach, pernicious vomiting of pregnancy, threatened abortion.; To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./1. Its decoction lower thab 1% concentration stimulates and that higher than 1% or the saturated solution of its volatile oil inhibits the intestines of guinea-pigs in vitro.2. Its volatile oil acts as stomachic tonic and exaggerates the diacharge of flatus.; Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy. | 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/瑶族/彝族/壮族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000309 | SCN5A | CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 | sodium voltage-gated channel alpha subunit 5 |
| TCMBANKGE000425 | DRD1 | DADR; DRD1A | dopamine receptor D1 |
| TCMBANKGE000633 | ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | adrenoceptor beta 2 |
| TCMBANKGE000701 | ESR2 | ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 | estrogen receptor 2 |
| TCMBANKGE000766 | ACHE | ACEE; ARACHE; N-ACHE; YT | acetylcholinesterase (Cartwright blood group) |
| TCMBANKGE000869 | DRD2 | D2DR; D2R | dopamine receptor D2 |
| TCMBANKGE000965 | CHRNA7 | CHRNA7-2; NACHRA7 | cholinergic receptor nicotinic alpha 7 subunit |
| TCMBANKGE001506 | ADRA1B | ADRA1; ALPHA1BAR | adrenoceptor alpha 1B |
| TCMBANKGE001816 | HRH1 | H1-R; H1R; HH1R; hisH1 | histamine receptor H1 |
| TCMBANKGE001943 | ADRA1D | ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 | adrenoceptor alpha 1D |
| TCMBANKGE003157 | CHRM2 | HM2 | cholinergic receptor muscarinic 2 |
| TCMBANKGE003625 | SLC6A4 | 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT | solute carrier family 6 member 4 |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE005535 | CHRM1 | HM1; M1; M1R | cholinergic receptor muscarinic 1 |
| TCMBANKGE006943 | CHRM3 | EGBRS; HM3; PBS | cholinergic receptor muscarinic 3 |
| TCMBANKGE008700 | CHRNA2 | - | cholinergic receptor nicotinic alpha 2 subunit |
| TCMBANKGE008702 | OPRM1 | LMOR; M-OR-1; MOP; MOR; MOR1; OPRM | opioid receptor mu 1 |
| TCMBANKGE008743 | OPRK1 | K-OR-1; KOP; KOR; KOR-1; KOR1; OPRK | opioid receptor kappa 1 |
| TCMBANKGE009294 | HTR3A | 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 | 5-hydroxytryptamine receptor 3A |
| TCMBANKGE009455 | CHRM5 | HM5 | cholinergic receptor muscarinic 5 |
| TCMBANKGE011923 | CHRM4 | HM4; M4R | cholinergic receptor muscarinic 4 |
| TCMBANKGE013826 | DRD5 | DBDR; DRD1B; DRD1L2 | dopamine receptor D5 |
| TCMBANKGE014423 | ADRA1A | ADRA1C; ADRA1L1; ALPHA1AAR | adrenoceptor alpha 1A |
| TCMBANKGE014625 | OPRD1 | DOP; DOR; DOR1; OPRD | opioid receptor delta 1 |
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