Compound Summary


  Compound Information

药名:

Emodinanthrone

别名:

1,6,8-trihydroxy-3-methyl-10-hydroanthracen-9-one; 6-Methyl-1,3,8,9-anthracenetetrol; SCHEMBL6046328; Frangula emodin anthrone; 2,4,5-trihydroxy-7-methylanthracen-10(9H)-one; 491-60-1; UNII-77C500W1A2; emodin anthrone; AC1L3UZ6; Frangulaemodinanthrone; Frangulaemodinanthranol; AN-15164; AIDS-002046; ZINC6070245; 1,3,8-Trihydroxy-6-methyl-10H-anthracen-9-one; Emodinanthranol; Protophyscihydrone; AKOS025401350; 1,3,8-Trihydroxy-6-methyl-9(10H)-Anthracenone; BDBM50060878; Emodinol; 1,3,8-trihydroxy-6-methyl-10H-anthracen-9-one; 1,3,8-Trihydroxy-6-methylanthrone; 9(10H)-Anthracenone, 1,3,8-trihydroxy-6-methyl-; CHEMBL122192; Emodin anthrone; AC-1208; 491E601; D00BSX; emodin anthrone ; DTXSID80197684; LAJSXCAVRQXZIO-UHFFFAOYSA-N; BC228045; AIDS002046; 77C500W1A2

分子式:

C15H12O4

Smiles:

CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2)C=C(C=C3O)O

成分:

HBIN025052

OB_score:

24.720657

CAS_id:

491-60-1

SymMap_id:

SMIT05436;SMIT15237

TCMID_id:

6776

TCMSP_id:

MOL003353

PubChem_id:

122635


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004552 Rumex dentatus 牛舌草 To clear heat and resolve toxin, kill worms and relieve itch./Red swollen breast.
TCMBANKHE003373 Exocarpium Citri grandis 化橘红 To dispel cold, eliminate damp and phlegm, and arrest emesis or nausea./Treatment of cough, itching of the throat and profuse expectoration in colds, nausea, vomiting and epigastric distension caused by improper diet or excessive drinking.
TCMBANKHE003426 Fructus Leonuri 茺蔚子 To activate blood circulation and regulate menstruation, to subdue hyperactivity of the liver, and to clear the eye of opacity./Treatment of menstrual disorders, amenorrhea, hysmenorrhea, inflammation of the eye with formation of corneal opacity, dizziness and headache.
TCMBANKHE003799 Fructus Forsythiae 连翘 To remove toxic heat, to cause subsidence of sweeling,and to eliminate modulation./Influenza in early stage, common cold in early stage, wind-heat common cold, encephalitis, hepatitis, tuberculosis, warm disease, heat strangury with inhibited pain, welling abscess, welling abscess and flat abscess, toxin swelling, scrofula, goiter and tuberculosis, throat impediment.
TCMBANKHE004160 Semen Cassiae;Semen Sene 决明子 To remove heat from the liver, to improve eyesight, and to relax bowels./See Cassia obtusifolia.
TCMBANKHE004384 Epimedium koreanum 朝鲜淫羊藿 See Epimedium brevicornum ./See Epimedium brevicornum.
TCMBANKHE006135 Rheum wittrocki 天山大黄
TCMBANKHE006313 Radix et Rhizoma Rhei 大黄 To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.
TCMBANKHE008555 Polygonum multiflorum 何首乌 To lower cholesterol, enrich yin and nourish blood, moisten intestines and free stool, interrupt malaria, dispel wind, resolve toxin./Backache, neurasthenia, hyperlipemia, neurosis, insomnia, dizziness due to anemia, palpitation, limp aching lumbus and knees due to liver kidney yin vacuity, premature graying in beard and hair, tinnitus, emission, intestinal dry and constipation, enduring malaria, wind papule itching, sore and welling abscess, scrofula, hemorrhoids.
TCMBANKHE005401 Rumex crispus 牛耳大黄 To clear heat and resolve toxin, cool blood and stanch bleeding, free stool and kill worms./Acute hepatitis, chronic hepatitis, enteritis, dysentery, chronic trachitis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, heat bind constipation, swelling toxin of welling abscess and flat abscess, scab and lichen, bald sores.
TCMBANKHE005748 Rheum tanguticum 唐古特大黄 See Rheum officinale./See Rheum officinale.
TCMBANKHE005948 Rhamnus frangula [Syn. Frangula alnus] 欧鼠李 To moisten intestines and free stool./Habitual constipation, abdominal pain.
TCMBANKHE005954 Radix Pulsatillae 白头翁 1. To clear heat and release toxins; 2. To cool the blood and stop dysentery/Amebic dysentery, nosebleed, flooding and spotting, bleeding from hemorrhoids, cold-heat warm malaria, vaginal discharge, pudendal itch, eczema, scrofula, welling abscess, painful red eyes, neurodermatitis.
TCMBANKHE006028 Rhamnus davurica 鼠李 To clear heat and resolve toxin, drain precipitation and kill worms, relieve cough and dispel phlegm./Sore and welling abscess, scrofula, scab and lichen, decayed toothache, mout h sore, abdominal distention and constipation, cough of phlegm asthma, edema distention fullness.
TCMBANKHE007163 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE008975 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE008246 Myrsine africana 铁子 To dispel wind and relieve pain, clear heat and disinhibit damp, promote contraction and stanch bleeding./Wind-damp impediment pain, toothache, diarrhea, dysentery, flooding, hematochezia, tuberculosis and hemoptysis.
TCMBANKHE008463 Rhamnus frangula [Syn. Frangula alnus] 欧鼠李;偶数里 To moisten intestines and free stool./Habitual constipation, abdominal pain.
TCMBANKHE005418/YNS-102 Rhizoma Polygoni cuspidati|Polygonum cuspidatum Sieb.et Zucc. 虎杖 虎杖叶 云南药材标准:第一册 平肝潜阳,祛痰息风。用于肝阳上亢,血压偏高,头晕头昏|To dispel wind and damp, to eliminate blood stasis and alleviate pain, to relieve cough, and to resolve phlegm./Hyperlipemia, impediment pain in joints, damp-heat jaundice, toxic jaundice, child jaundice, amenorrhea, hepatitis, appendicitis, candida vaginitis, concretion and conglomeration, cough with profuse phlegm, burns and scalds, knocks and falls, swelling toxin of welling abscess and sore.
TCMBANKHE009081 Boehmeria platanifolia [Syn. Boehmeria tricuspis] 赤麻 To promote astriction and stanch bleeding, clear heat and resolve toxin./Hemoptysis, spontaneous external bleeding, hematochezia, hematuria, flooding and spotting, knocks and falls, innominate toxin swelling, sores.
TCMBANKHE004855/YNS-170 Ventilago calyculata|Ventilago calyculata Tul. 毛果翼核果|翼核果 毛翼核果藤 云南药材标准:第三册 养血祛风,舒筋活络。用于风湿筋骨痛,跌打损伤,腰肌劳损,贫血头晕,四肢麻木,月经不调
TCMBANKHE006959/YNS-135/YEM-14 Semen Cassiae;Semen Sene|Cassia tora Linn.|Cassia tora L. 决明子;草决明|决明 决明根|草决明 云南药材标准:第三册|云南民族药物志:第一卷 安神补脑,清肝明目,理气止痛。主治失眠多梦,入睡易惊,腹内痉挛剧痛,腹部包块,黄疸,疟疾。|To remove heat from the liver, to improve eyesight, and to relax bowels.Treatment of inflammation in the eye with pain, photophobia and lacrimination, headache, dizziness, blurred vision and constipation./See Cassia obtusifolia.1. Oral adminstration of the hearbal powder can inhibit the rising of serum cholesterol and formation of atherosclerosis in rabbits.2. Its tincture and infusion can inhibit the myocardium of toad in vitro, and contract th eblood vessels of lower limbs.3. Its infusion can lower the blood pressure in dogs, cats and rabbits.4. Chrysophanol, one of the active components, is a laxative.5. Bacteriostatic. 傣族/基诺族/拉祜族/傈僳族/苗族/佤族/彝族/藏族
TCMBANKHE005278/YEM-158 Cassia occidentalis|Cassia occidentalis L. 望江南 望江南 云南民族药物志:第一卷 To clear lung, clear liver, calm asthma, disinhibit urine, free stool, resolve toxin and disperse swelling, lower blood pressure./Cough and asthma, hypertension, headache and red eyes, dribbling urination, constipation, swelling toxin of welling abscess and sore, snake or insect bites. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE006828/YEM-467/XU-369 Polygonum perfoliatum|Polygonum perfoliatum L. 杠板归根|杠板归 杠板归 云南民族药物志:第三卷|云南省昭通市盐津县普洱镇 To resolve toxin and disperse swelling./Mouth-level nape sore, hemorrhoids and fistulas. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/佤族/瑶族/壮族
TCMBANKHE008264/YEM-551 Artemisia scoparia [Syn. Artemisia capillaris var. scoparia]|Artemisia capillaris Thunb. 黄蒿|茵陈蒿 茵陈 云南民族药物志:第三卷 See Artemisia capillaris./See Artemisia capillaris. 阿昌族/傣族/德昂族/景颇族/傈僳族/瑶族/彝族/藏族/壮族
TCMBANKHE006999/YEM-606 Rumex japonicus|Rumex nepalensis Spreng. 羊蹄|尼泊尔酸模 土大黄 云南民族药物志:第三卷 To clear heat and free stool, cool blood and stanch bleeding, kill worms and relieve itch./Constipation, blood ejection, spontaneous external bleeding, intestinal wind bleeding, bleeding from hemorrhoids, flooding and spotting, scab and lichen, bald white scalp sore, swelling toxin of welling abscess and sore, knocks and falls. 白族/布依族/哈尼族/基诺族/傈僳族/苗族/纳西族/佤族/彝族/藏族
TCMBANKHE006536/YEM-606 Rumex nepalensis|Rumex nepalensis Spreng. 尼泊尔羊蹄|尼泊尔酸模 土大黄 云南民族药物志:第三卷 See Rumex japonicus./See Rumex japonicus. 白族/布依族/哈尼族/基诺族/傈僳族/苗族/纳西族/佤族/彝族/藏族
TCMBANKHE004455/YEM-744/XU-850 Rheum palmatum|Rheum palmatum L. 掌叶大黄 掌叶大黄 云南民族药物志:第四卷|西藏昌都地区芒康县 See Rheum officinale./See Rheum officinale. 阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族
TCMBANKHE007363/YEM-744/XU-850 Radix et Rhizoma Rhei|Rheum palmatum L.|Rheum palmatum 大黄; 生锦纹; 生军|掌叶大黄 掌叶大黄 云南民族药物志:第四卷|西藏昌都地区芒康县 To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge.; Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.; 1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect. 阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE009857 THRB C-ERBA-2; C-ERBA-BETA; ERBA2; GRTH; NR1A2; PRTH; THR1; THRB1; THRB2 thyroid hormone receptor beta