Compound Summary

  Compound Information

TCMBANKIN025923

药名:	cirsiliol
别名:	2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxychromen-4-one; 6,7-Dimethoxy-5,3',4'-trihydroxyflavone; AKOS025287589; 3',4',5-trihydoxy-6,7-dimethoxyflavone; CTK8I3082; 3',4',5-Trihydroxy-6,7-dimethoxyflavone; ST50331608; LS-193892; BDBM50025321; DTXSID60187907; AC1L4N9W; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-; 5,3'',4''-Trihydroxy-6,7-dimethoxyflavone; CHEMBL72637; AC1Q6AIE; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one; 5,3',4'-trihydroxy-6,7-dimethoxyflavone; 34334-69-5; C10033; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-chromone; ZINC4098510; MCULE-9854332110; 2-(3,4-Dihydroxy-phenyl)-5-hydroxy-6,7-dimethoxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one; MFCD00210577; ST5331608; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4-chromenone; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-chromen-4-one; MolPort-009-754-980; CHEBI:3719; FT-0620861; 6-methoxyluteolin 7-methyl ether; LMPK12111227; SCHEMBL1614677; Cirsiliol; 3',4',5-TRIHYDROXY-6,7-DIMETHOXY FLAVONE
分子式:	C17H14O7
Smiles:	COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O)OC
成分:	HBIN020718
SymMap_id:	SMIT01338;SMIT08847
TCMID_id:	3743
TCMSP_id:	MOL007401
PubChem_id:	160237

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002762	Radix et Rhizoma Thalictri	马尾莲			Influenza, fever in children, common cold with fever, measles papules, malaria, damp-heat diarrhea dysentery, jaundice, red eyes with gall.
TCMBANKHE003004	Achillea fragrantissima
TCMBANKHE004166	Cirsium chinense	苦芺			To clear heat and resolve toxin, cool blood and quicken blood./Vexation and oppression due to summerheat-heat, flooding and spotting, blood ejection from knocks and falls, hemorrhoids, clove sore.
TCMBANKHE004937	Salvia officinalis	药用丹参
TCMBANKHE006376/YEM-362/XU-286	Cirsium lineare|Cirsium lineare(Thunb.)Sch.-Bip.	条叶蓟|滇小蓟|线叶蓟	条叶蓟	云南民族药物志：第二卷|陕西省安康市旬阳县	To quicken blood and dissipate stasis, resolve toxin and disperse swelling./Menstrual disorder, amenorrhea, dysmenorrhea, mastitis, knocks and falls, urinary tract infection, welling abscess and boil, snake bite.	佤族/瑶族
TCMBANKHE006570/YEM-68	Herba Artemisiae Annuae|Artemisia annua L.	青蒿|黄花蒿	黄花蒿	云南民族药物志：第一卷	To remove summer-heat, to relieve consumptive fever,and to stop malarial attacks./See Artemisia annua.	阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族
TCMBANKHE008476/YEM-68	Artemisia annua|Artemisia annua L.	黄花蒿	黄花蒿	云南民族药物志：第一卷	To clear heat, resolve summerheat, eliminate steam, interrupt malaria./Summerheat-heat, summerheat-damp, damp warmth, yin vacuity fever, malaria, jaundice.	阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族
TCMBANKHE006261/YEM-689	Rhizoma Phragmitis|Phragmites communis Trin.	芦根|芦苇	芦苇	云南民族药物志：第四卷	To remove heat, to promote the production of body fluid, to relieve emesis, and to alleviate dysuria./Febrile diseases with vexation and thirst, stomach heat vomiting, lung heat cough, pulmonary welling abscess, heat strangury with inhibited pain.	阿昌族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/水族/佤族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000749	ALOX5	5-LO; 5-LOX; 5LPG; LOG5	arachidonate 5-lipoxygenase
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000978	GCLM	GLCLR	glutamate-cysteine ligase modifier subunit
TCMBANKGE000994	AKR1B1	ADR; ALDR1; ALR2; AR	aldo-keto reductase family 1 member B
TCMBANKGE001041	ALOX15	12-LOX; 15-LOX; 15-LOX-1; LOG15	arachidonate 15-lipoxygenase
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001079	CYP1A1	AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX	cytochrome P450 family 1 subfamily A member 1
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001296	ALOX12	12-LOX; 12S-LOX; LOG12	arachidonate 12-lipoxygenase, 12S type
TCMBANKGE001581	AKR1C4	3-alpha-HSD; C11; CDR; CHDR; DD-4; DD4; HAKRA	aldo-keto reductase family 1 member C4
TCMBANKGE002727	ALOXE3	ARCI3; E-LOX; eLOX-3; eLOX3	arachidonate lipoxygenase 3
TCMBANKGE003643	F7	SPCA	coagulation factor VII
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE004437	PYGM	GSD5	glycogen phosphorylase, muscle associated
TCMBANKGE005198	AKR1E2	AKR1CL2; AKRDC1; LoopADR; TAKR; hTSP; htAKR	aldo-keto reductase family 1 member E2
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE006907	AKR1A1	ALDR1; ALR; ARM; DD3; HEL-S-6	aldo-keto reductase family 1 member A1
TCMBANKGE008022	AKR1C3	DD3; DDX; HA1753; HAKRB; HAKRe; HSD17B5; PGFS; hluPGFS	aldo-keto reductase family 1 member C3
TCMBANKGE008077	AKR1C2	AKR1C-pseudo; BABP; DD; DD-2; DD/BABP; DD2; DDH2; HAKRD; HBAB; MCDR2; SRXY8; TDD	aldo-keto reductase family 1 member C2
TCMBANKGE009472	AKR1B10	AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI	aldo-keto reductase family 1 member B10
TCMBANKGE010462	ALOX12B	12R-LOX; ARCI2	arachidonate 12-lipoxygenase, 12R type
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE013428	ALOX15B	15-LOX-2	arachidonate 15-lipoxygenase type B
TCMBANKGE013955	AKR1B15	AKR1B10L; AKR1B10L, AK1R1B7; AKR1R1B7	aldo-keto reductase family 1 member B15
TCMBANKGE014269	AKR1C1	2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB	aldo-keto reductase family 1 member C1
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1
TCMBANKGE015062	AKR1D1	3o5bred; CBAS2; SRD5B1	aldo-keto reductase family 1 member D1