Compound Summary

  Compound Information

TCMBANKIN027075

药名:	GARDENOSIDE
别名:	Gardenoside; C09779; CHEBI:5277; 24512-62-7; methyl (1R,4aR,7R,7aR)-7-hydroxy-7-(hydroxymethyl)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4a,7a-dihydro-1H-cyclopenta[c]pyran-4-carboxylate; gardenoside; methyl (1R,4aR,7R,7aR)-1-(beta-D-glucopyranosyloxy)-7-hydroxy-7-(hydroxymethyl)-1,4a,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
分子式:	C17H24O11
Smiles:	COC(=O)C1=COC(C2C1C=CC2(CO)O)OC3C(C(C(C(O3)CO)O)O)O
成分:	HBIN027370
OB_score:	10.552127
CAS_id:	24512-62-7
SymMap_id:	SMIT06454;SMIT15509
TCMID_id:	8230
TCMSP_id:	MOL004554
PubChem_id:	53297356

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002659	Concretio Silicea Bambusae	天竺黄			For desolving phlegm
TCMBANKHE008657	Genipa americana	京尼平
TCMBANKHE007098	Fructus Gardeniae	栀子;生山栀			1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness;4.Treatment of febrile diseases with restlessness, jaundice with dark urine, hematuria with difficult painful urination, hemoptysis and epistaxis caused by heat in the blood, inflammation of the eye, boils and sores, external use for sprains and bruises.Fructus Gardeniae (charred): Hemoptysis, epistaxis, hematuria and abnormal uterine bleeding caused by heat in the blood./Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria.1. The active components such as crocin, crocetin, genipin, or alcoholic extract protect the liver from carbon tetrachloride and increasing biliary secretion. Oral use of its decoction induce gallbladder contraction.2. Oral or intraperitoneal use of its decoction and alcoholic extract exerts a sustained hypotensive effect in anaesthetized and un-anaesthetized animals.3. Hemostatic.
TCMBANKHE006865/YEM-745/XU-411	Gardenia jasminoides var. grandiflora|Gardenia jasminoides(L.)Ellis|Gardenia jasminoides	水蛭|栀子	栀子	云南民族药物志：第四卷|广东省廉江市石岭镇	To clear heat and resolve toxin, disperse swelling and relieve pain./Heat toxin, jaundice, nosebleed(epistaxis), nephritis with edema, sprain and contusion.	阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/水族/瑶族/彝族/壮族
TCMBANKHE005522/YEM-745/XU-411	Fructus Gardeniae|Gardenia jasminoides(L.)Ellis|Gardenia jasminoides	栀子	栀子	云南民族药物志：第四卷|广东省廉江市石岭镇	1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness/Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria.	阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/水族/瑶族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2