Compound Summary


  Compound Information

药名:

smilagenin

别名:

EINECS 204-775-8; CHEBI:28933; (25R)-Spirostane-3beta-ol; C08913; 5beta-Spirostan-3beta-ol, (25R)- (8CI); (25R)-Spirostan-3.beta.-ol; Isosarsasapogenin; Spirostan-3-ol, (3.beta.,5.beta.,25R)-; Spirostan-3-ol, (3beta,5beta,25R)- (9CI); NSC93747; NSC 93747; (25R)-5beta-Spirostan-3beta-ol; SMP1_000275; SCHEMBL180193; AI3-44895; Isosarsapogenin; (25R)-Spirostan-3beta-ol; 126-18-1; Smilagenin; 5.beta.-Spirostan-3.beta.-ol, (25R)-

分子式:

C27H44O3

Smiles:

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1

成分:

HBIN044212

SymMap_id:

SMIT01619;SMIT05898

TCMID_id:

20009

TCMSP_id:

MOL003894

PubChem_id:

91439


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004260 Radix Ginseng 人参 To reinforce the vital energy, to remedy collapse and restore the normal pulse, to benefit the spleen and lung, to promote the production of body fluid, and to calm the nerves./Qi vacuity and verging on desertion, cold limbs and faint pulse, reduced food intake due to spleen vacuity, cough and asthma due to lung vacuity, fluid damage and thirst, diabetes mellitus due to internal heat, enduring illness qi vacuity, fright palpitation and insomnia, impotence, uterus cold, cardiac failure.
TCMBANKHE000698 Radix Asparagi 天冬 To replenish yin, promote fluid secretion and moisten the lung./1. Asparamide is an expectorant, antitussive and antiasthmatic.2. Inhibiting the cell growth of acute lymphocytic, acute monocytic and chronic granulocytic leukemias in vitro.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001367 Semen Hyoscyami 天仙子 To relieve spasm and pain, and to cause tranquilization./1. Antisudorific, saliva antisecretory and mydriatic.2. Relaxing the smooth muscles.3. Increasing heart rate and exciting the respiratory center.
TCMBANKHE003600 Gummi Elasticum 天然橡胶
TCMBANKHE005462 Bulbus Allii Macrostemi 薤白 To remove the retained phlegm from the chest, promote the flow of qi and relieve its stagnation./Chest impediment, phlegm-rheum cough asthma, diarrhea and tenesmus.
TCMBANKHE004287 Radix Achyranthis bidentatae 牛膝 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat.
TCMBANKHE004439 Rhizoma Smilacis Glabrae 土茯苓 To remove damp, to counteract toxicity, and to improve the mobility of joints./Damp-heat with strangury turbidity, vaginal discharge, swollen welling abscess, scrofula, scab and lichen, syphilis, mercurial poisoning.
TCMBANKHE008687 Rhizoma Anemarrhee 知母 To remove heat and quench fire, and to promote the production of body fluid and relieve dryness syndromes./Diabetes mellitus, warm heat disease, ardent fever with vexation and thirst, cough and asthma, dry cough, constipation, steaming bone tidal fever, vacuity vexation and insomnia, strangury-turbidity.
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE008911/YEM-126 Radix Achyranthis bidentatae|Achyranthes bidentata Blume 牛膝;怀牛膝|牛膝 牛膝 云南民族药物志:第一卷 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward.Treament of soreness of the lumbar and knee joints with weakness inthe legs, amenorrhea with mass formation in the abdomen, dizziness due to hyperactivity of the liver./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000737 PGR NR3C3; PR progesterone receptor
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor