Compound Summary


  Compound Information

药名:

matrine

别名:

.alpha.-Matrine; Matrene, (+)-; STOCK1N-36535; Matrine; BRN 0085851; (+)-Matrine; ZINC4196454; 519-02-8; Matridin-15-one (9CI); C10774; NSC146051; 5-24-02-00301 (Beilstein Handbook Reference); NSC 146051

分子式:

C15H24N2O

Smiles:

C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1

成分:

HBIN034558

OB_score:

63.774931

CAS_id:

519-02-8

SymMap_id:

SMIT00239

TCMID_id:

13599

TCMSP_id:

MOL005944

PubChem_id:

91466


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000946 Flos Mume 梅花 To ease the mind, the regulate the stomach function, to resolve phlegm, and counteract toxicity./Treament of depression with fidgetness, epigastric pain due to stagnation of qi of the liver and stomach, globus hystericus, scrofula, ulcers.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE006167 Herba Corydalis bungeae 苦地丁 Influenza, infection of upper respiratory tract, tonsillitis, infective hepatitis, enteritis, dysentery, nephritis, parotitis, conjunctivitis, acute appendicitis, clove sore and swollen welling abscess, scrofula.
TCMBANKHE001092 苦豆草
TCMBANKHE001142 木菊
TCMBANKHE001194 Herba Sophorae Alopecuroidis 苦甘草 1. To clear heat and toxic material, deprive dampness and kill parasites. For sorethroat, dysentery, trichomonas enteritis, toothache, stomachache and leucorrhagia, external use for tinea and eczema. 2. To relieve dyspnea and cough. 3. Anticarcinogenic. For malignant hydatidiform mole, chorionic epithelioma and leukemia./1. To clear heat and toxic material, deprive dampness and kill parasites. For sorethroat, dysentery, trichomonas enteritis, toothache, stomachache and leucorrhagia, external use for tinea and eczema. 2. To relieve dyspnea and cough. 3. Anticarcinogenic. F
TCMBANKHE002799 Artemisia caruthii
TCMBANKHE003410 柔枝槐
TCMBANKHE003666 沙参槐
TCMBANKHE005727 南鹤虱
TCMBANKHE005787 Sophora viciifolia 白刺花 To clear heat and disinhibit throat, cool blood and disperse swelling./Swelling pain in throat, cough, hepatitis, dysentery, strangury syndrome, edema, hematuria, nosebleed(epistaxis), hematochezia.
TCMBANKHE004344 南鹤虱 Ascariasis, oxyuria disease, taeniasis, ancylostomiasis, abdominal pain due to worm accumulation, child gan accumulation, pudendal itch.
TCMBANKHE004613 flos Sophorae 槐花 To arrest bleeding by reducing heat in blood, and to quench excess fire in the liver./1. Its component rutin decreases capillay permeability. 2. Lowering blood pressure transiently in anesthetized dog. 3. Inhibiting the growth of various dermatomyces.
TCMBANKHE004838 Radix Sophorae Tonkinensis 山豆根 To remove toxic heat, promote the subsidence of swelling, and soothe the sore throat./Septicemia, ulcer of uterine cervix, chronic cervicitis, bacillary dysentery, enteritis, hydatid moles, chorioblastoma, asthma, chronic bronchitis, acute tonsillitis, laryngitis, accumulated fire toxin, swelling pain in throat, gingiva painful swelling.
TCMBANKHE004910 Cuscuta australis 南方菟丝子 See Cuscuta chinensis ./See Cuscuta chinensis .
TCMBANKHE005066 Sophora tetraptera 四翅槐
TCMBANKHE007073 Semen Cuseutae;Semen Cuseutae;Semen Cuscutae 菟丝子 To arrest seminal discharge and abnormal urination, prevent abortion, improve eyesight and relieve diarrhea by replenishing and tonifying the liver and the kidney;Treatment of impotence, seminal emission, dripping of urine after urination, enuresis, frequent urination, aching and weakness of the loins and knees, blurred vision and tinnitus, threatened abortion due to hypofunction of the kidney, diarrhea due to hypofunction of the spleen and the kidney, external use for vitiligo./1. Cardiotonic. 2. Promoting lymphocyte-blastogenesis.
TCMBANKHE005410 Sophora chrysophylla 黄叶槐
TCMBANKHE007521 Sophora alopecuroides 苦豆子 To clear heat and dry damp, kill worms and relieve pain./Dysentery, stomachache, excessive leukorrhea, eczema, sore and boil, intractable lichen.
TCMBANKHE006056 Rhizoma Menispermi 北豆根 To remove toxic heat and relieve rheumatic pains./Treatment of sore throat, colitis, dysentery, rheumatic arthralgia.
TCMBANKHE008503 Radix Sophorae flavescentis 苦参 To remove heat and damp, to kill parasites, and to cause diuresis./Arrhythmia, otitis media, acute conjunctivitis, chronic conjunctivitis, trichomoniasis, septicemia, edema, damp-heat diarrhea, intestinal wind bleeding, acute jaundice, inhibited urination, vaginal discharge, pudendal itch, scab and lichen, leprosy, itchy skin, eczema, damp toxin sore, suppurative nest sore.
TCMBANKHE008498 fructus Sophorae 槐角 For cooling blood and stopping bleeding
TCMBANKHE005405/YEM-157 Semen Cuseutae;Semen Cuseutae|Cuscuta chinensis Lam. 菟丝子 菟丝子 云南民族药物志:第一卷 To arrest seminal discharge and abnormal urination, prevent abortion, improve eyesight and relieve diarrhea by replenishing and tonifying the liver and the kidney./1. Cardiotonic. 2. Promoting lymphocyte-blastogenesis. 傣族/彝族/藏族
TCMBANKHE006499/YEM-675 Fructus Piperis|Piper nigrum L. 胡椒 胡椒 云南民族药物志:第四卷 To dispel cold from the stomach, and to eliminate phlegm./Vomiting with stomach cold, abdominal pain and diarrhea, inappetence, convulsion, epilepsy and profuse phlegm. 傣族/回族/傈僳族/佤族/彝族/藏族
TCMBANKHE008328/YEM-99 Sophora flavescens [Syn. Sophora angustfolia]|Sophora flavescens Ait. 苦参实|苦参 苦参 云南民族药物志:第一卷 To clear heat and resolve toxin, free stool, kill worms./Acute bacillary dysentery, constipation, ascariasis. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE006936/YEM-99 Sophora flavescens [Syn. Sophora angustfolia]|Sophora flavescens Ait. 苦参实|苦参 苦参 云南民族药物志:第一卷 To clear heat and resolve toxin, free stool, kill worms./Acute bacillary dysentery, constipation, ascariasis. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000199 ICAM1 BB2; CD54; P3.58 intercellular adhesion molecule 1
TCMBANKGE000445 CD44 CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1 CD44 molecule (Indian blood group)
TCMBANKGE000898 MYC MRTL; MYCC; bHLHe39; c-Myc MYC proto-oncogene, bHLH transcription factor
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE009215 IER3IP1 HSPC039; MEDS; PRO2309 immediate early response 3 interacting protein 1
TCMBANKGE012461 HPSE HPA; HPA1; HPR1; HPSE1; HSE1 heparanase