Compound Summary

  Compound Information

TCMBANKIN029162

药名:	18beta-glycyrrhetinic acid
别名:	AJ-72559; Rhetinic Acid; C02283; GLYCYRRHETINIC ACID; 18-beta-Glycyrrhetinic acid; 1449-05-4; Glycyrrhetic acid; Hidermart; CHEMBL230006; SMR000058239; SR-01000721867-5; NCGC00142473-03; 18beta-Glycyrrhetinic acid, purum, >=97.0% (T); UNII-P540XA09DR; Enoxolone (Glycyrrhetin); 107420-91-7; Enoxolone, Glycyrrhetinic acid; CCRIS 3962; LMPR0106150014; 18beta-Glycyrrhetic acid; 4-10-00-03775 (Beilstein Handbook Reference); BB_NC-0599; HMS2233P23; LS-7417; (3?)-3-Hydroxy-11-oxoolean-12-en-30-oic acid; Opera_ID_1048; D0U8IF; (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid; NSC-35350; Olean-12-en-30-oic acid, 3beta-hydroxy-11-oxo- (8CI); AC-1925; Glycyrrhetinic acid; (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-2,4a,6a,6b,9,9,12a-heptamethyl-10-oxidanyl-13-oxidanylidene-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid; HY-N0180; Arthrodont; Hidermart (TN); DTXSID9020669; SR-01000721867-3; MLS002207101; Enoxolona; Glycyrrhetinic acid (JAN); A-Hydroxy-11-oxoolean-12-en-30-olic acid; SR-01000721867-6; Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3beta,20beta)-; (3beta)-3-hydroxy-11-oxoolean-12-en-30-oic acid; subglycyrrhelinic acid; SCHEMBL18540; 471-53-4; Olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-; BG01168029; FT-0082445; BX-1; Glycyrrhetin; D00156; NCGC00017244-03; 202522-39-2; 18-beta-Glycyrrhetic acid; SR-01000721867-4; Enoxolonum [INN-Latin]; SBB006496; GM-1658; Q-201057; NSC-35347; NSC 35347; (5S,8S,15S,18S,1R,2R,10R,14R,20R)-18-hydroxy-1,2,5,8,15,19,19-heptamethyl-13-o xopentacyclo[12.8.0.0<2,11>.0<5,10>.0<15,20>]docos-11-ene-8-carboxylic acid; alpha-Glycyrrhetinic acid; Tox21_112726; 130100-EP2295411A1; ZINC19203131; Biosone; D08LGJ; Bio-0549; Enoxolone; 18beta-Glycyrrhetinic acid; 3?-Hydroxy-11-oxo-18?,20?-olean-12-en-29-oic acid; Enoxolone (Glycyrrhetinic acid); 50510_FLUKA; BDBM50233538; Uralenic acid; NCGC00017244-04; P540XA09DR; 18beta-glycyrrhetic acid; C30H46O4; Jintan; Olean-12-en-30-oic acid, 3beta-hydroxy-11-oxo-; CAS-471-53-4; Tox21_200799; SR-01000721867; Enoxolone (INN); MLS001146949; MLS000028748; [(125)I] RB129; G10105_ALDRICH; (3beta,20beta)-3-Hydroxy-11-oxo-olean-12-en-29-oic acid; s2296; CCG-208506; 8055-71-8; EINECS 207-444-6; (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid; Enoxolona [INN-Spanish]; GlycyrrhetinicAcid; 18b-Glycyrrhetic acid; AC1L1UIT; 130100-EP2269977A2; KS-1262; Glycyrrhetinate; Glycyrrhetinic acid [JAN]; (3alpha,5xi,8alpha,9xi,17alpha,18xi)-3-hydroxy-11-oxoolean-12-en-29-oic acid; BC201656; Enoloxone; Enoxolone [INN:BAN:DCF]; 18 beta-glycyrrhetinic acid; 3beta-Hydroxy-11-oxo-18beta,20beta-olean-12-en-29-oic acid; enoxolone; DSSTox_RID_75722; 18 beta-Glycyrrhetintic Acid; DSSTox_CID_669; 3-Glycyrrhetinic acid; 3beta-hydroxy-11-oxoolean-12-en-29-oic acid; NCGC00181115-01; Enoxolone; STX-352; AKOS016036757; 15301-63-0; G0149; MFCD00003706; ST24038257; Enoxolone, European Pharmacopoeia (EP) Reference Standard; ST056310; (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-13-keto-2,4a,6a,6b,9,9,12a-heptamethyl-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid; AKOS015960428; 471G534; NCGC00258353-01; DB13089; Tox21_110804; CBW; DSSTox_GSID_20669; D0F6IV; MolPort-002-507-130; A827163; (3beta,5beta,14beta)-3-Hydroxy-11-Oxoolean-12-En-29-Oic Acid; 18beta-Glycyrrhetinic acid, 97%; CHEBI:30853; AC-8906; AN-14462; API0002854; BRN 2229654; Glyciram; 18beta-Glycyrrhetinic acid; MCULE-4676598997; 3beta-Hydroxy-11-oxoolean-12-en-30-oic acid; 3-beta-Hydroxy-11-oxoolean-12-en-30-oic acid; BG00824432; Enoxolone [BAN:DCF:INN]; CS-W020624; S00284; Enoxolonum; 299198-00-8
分子式:	C30H46O4
Smiles:	CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C
成分:	HBIN002095
OB_score:	22.05261
CAS_id:	471-53-4
SymMap_id:	SMIT00577
TCMID_id:	23092
TCMSP_id:	MOL004804
PubChem_id:	10114
DrugBank_id:	DB13089

---

   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000312	Radix Glycyrrhizae Preparata	炙甘草			Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE000541		甘草头
TCMBANKHE000702	Radix Glycyrrhizae Praeparata	炙草			Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE001384	Radix Glycyrrhizae uralensis	甘草稍
TCMBANKHE003349		甘草节
TCMBANKHE003728	Radix Glycyrrhizae	甘草			To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE007721	Exocarpium Benincasae	冬瓜皮			1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE008131	Herba Abri	鸡骨草			To remove toxic heat, and to relieve the depressed liver and alleviate pain./Icterohepatitis, stomachache, wind-damp bone pain, stasis pain from knocks and falls, mammary welling abscess.

---

   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

---

   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000009	GJA1	AVSD3; CMDR; CX43; EKVP; EKVP3; GJAL; HLHS1; HSS; ODDD; PPKCA	gap junction protein alpha 1
TCMBANKGE000139	POR	CPR; CYPOR; P450R	cytochrome p450 oxidoreductase
TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE000199	ICAM1	BB2; CD54; P3.58	intercellular adhesion molecule 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000264	ABCB1	ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1	ATP binding cassette subfamily B member 1
TCMBANKGE000276	NOS1	IHPS1; N-NOS; NC-NOS; NOS; bNOS; nNOS	nitric oxide synthase 1
TCMBANKGE000328	PTPN11	BPTP3; CFC; JMML; METCDS; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2	protein tyrosine phosphatase non-receptor type 11
TCMBANKGE000533	SLCO1B1	HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2; OATPC; SLC21A6	solute carrier organic anion transporter family member 1B1
TCMBANKGE000639	HRAS	C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras	HRas proto-oncogene, GTPase
TCMBANKGE000646	DECR1	DECR; NADPH; SDR18C1	2,4-dienoyl-CoA reductase 1
TCMBANKGE001107	NOS3	ECNOS; eNOS	nitric oxide synthase 3
TCMBANKGE001123	CTNNB1	CTNNB; EVR7; MRD19; NEDSDV; armadillo	catenin beta 1
TCMBANKGE001171	SRC	ASV; SRC1; THC6; c-SRC; p60-Src	SRC proto-oncogene, non-receptor tyrosine kinase
TCMBANKGE001477	RDH8	PRRDH; SDR28C2	retinol dehydrogenase 8
TCMBANKGE001528	DHRS7B	CGI-93; SDR32C1	dehydrogenase/reductase 7B
TCMBANKGE001581	AKR1C4	3-alpha-HSD; C11; CDR; CHDR; DD-4; DD4; HAKRA	aldo-keto reductase family 1 member C4
TCMBANKGE001692	RDH12	LCA13; RP53; SDR7C2	retinol dehydrogenase 12
TCMBANKGE002099	DHRS7C	SDR32C2	dehydrogenase/reductase 7C
TCMBANKGE002369	RDH5	9cRDH; HSD17B9; RDH1; SDR9C5	retinol dehydrogenase 5
TCMBANKGE002388	NR3C2	MCR; MLR; MR; NR3C2VIT	nuclear receptor subfamily 3 group C member 2
TCMBANKGE002475	SDR9C7	ARCI13; RDHS; SDR-O; SDRO	short chain dehydrogenase/reductase family 9C member 7
TCMBANKGE002555	HSD11B1	11-DH; 11-beta-HSD1; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1	hydroxysteroid 11-beta dehydrogenase 1
TCMBANKGE002793	JUP	CTNNG; DP3; DPIII; PDGB; PKGB	junction plakoglobin
TCMBANKGE003092	HSD11B1L	11-DH3; 11-beta-HSD3; HSD1L; HSD3; SCDR10; SCDR10B; SDR26C2	hydroxysteroid 11-beta dehydrogenase 1 like
TCMBANKGE003649	RDH14	PAN2; SDR7C4	retinol dehydrogenase 14
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE004938	BDH1	BDH; SDR9C1	3-hydroxybutyrate dehydrogenase 1
TCMBANKGE005304	RDH10	SDR16C4	retinol dehydrogenase 10
TCMBANKGE005507	HPGD	15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1	15-hydroxyprostaglandin dehydrogenase
TCMBANKGE005699	RDH16	RODH-4; SDR9C8; hRDH-E	retinol dehydrogenase 16
TCMBANKGE005781	CBR1	CBR; SDR21C1; hCBR1	carbonyl reductase 1
TCMBANKGE005811	HSD17B2	EDH17B2; HSD17; SDR9C2	hydroxysteroid 17-beta dehydrogenase 2
TCMBANKGE006373	TYW1	RSAFD1; TYW1A; YPL207W	tRNA-yW synthesizing protein 1 homolog
TCMBANKGE006375	SLCO1B3	HBLRR; LST-2; LST-3TM13; LST3; OATP-8; OATP1B3; OATP8; SLC21A8	solute carrier organic anion transporter family member 1B3
TCMBANKGE006724	REN	HNFJ2	renin
TCMBANKGE006866	HSD11B2	AME; AME1; HSD11K; HSD2; SDR9C3	hydroxysteroid 11-beta dehydrogenase 2
TCMBANKGE006933	DHRS4L2	SDR25C3	dehydrogenase/reductase 4 like 2
TCMBANKGE007026	CBR4	SDR45C1	carbonyl reductase 4
TCMBANKGE008022	AKR1C3	DD3; DDX; HA1753; HAKRB; HAKRe; HSD17B5; PGFS; hluPGFS	aldo-keto reductase family 1 member C3
TCMBANKGE008077	AKR1C2	AKR1C-pseudo; BABP; DD; DD-2; DD/BABP; DD2; DDH2; HAKRD; HBAB; MCDR2; SRXY8; TDD	aldo-keto reductase family 1 member C2
TCMBANKGE008362	PTGR2	HEL-S-298; PGR2; ZADH1	prostaglandin reductase 2
TCMBANKGE008641	HSD17B13	HMFN0376; NIIL497; SCDR9; SDR16C3	hydroxysteroid 17-beta dehydrogenase 13
TCMBANKGE008796	HSD17B6	HSE; RODH; SDR9C6	hydroxysteroid 17-beta dehydrogenase 6
TCMBANKGE009006	C2orf81	hCG40743	chromosome 2 open reading frame 81
TCMBANKGE009091	SDR16C5	EPHD-2; RDH#2; RDH-E2; RDHE2; retSDR2	short chain dehydrogenase/reductase family 16C member 5
TCMBANKGE009446	DHRS12	SDR40C1	dehydrogenase/reductase 12
TCMBANKGE009863	MTRR	MSR; cblE	5-methyltetrahydrofolate-homocysteine methyltransferase reductase
TCMBANKGE010106	HSD17B11	17-BETA-HSD11; 17-BETA-HSDXI; 17BHSD11; DHRS8; PAN1B; RETSDR2; SDR16C2	hydroxysteroid 17-beta dehydrogenase 11
TCMBANKGE010124	DHRS1	SDR19C1	dehydrogenase/reductase 1
TCMBANKGE010905	ANPEP	APN; CD13; GP150; LAP1; P150; PEPN	alanyl aminopeptidase, membrane
TCMBANKGE011011	DHRSX	CXorf11; DHRS5X; DHRS5Y; DHRSXY; DHRSY; SDR46C1; SDR7C6	dehydrogenase/reductase X-linked
TCMBANKGE011293	RDH11	ARSDR1; CGI82; HCBP12; MDT1; PSDR1; RALR1; RDJCSS; SCALD; SDR7C1	retinol dehydrogenase 11
TCMBANKGE011300	DHRS13	SDR7C5	dehydrogenase/reductase 13
TCMBANKGE011356	NDOR1	CIAE1; NR1; bA350O14.9	NADPH dependent diflavin oxidoreductase 1
TCMBANKGE011682	HSD17B1	17-beta-HSD; 20-alpha-HSD; E2DH; EDH17B2; EDHB17; HSD17; SDR28C1	hydroxysteroid 17-beta dehydrogenase 1
TCMBANKGE011927	CBR3	HEL-S-25; SDR21C2; hCBR3	carbonyl reductase 3
TCMBANKGE012486	BDH2	DHRS6; EFA6R; PRO20933; SDR15C1; UCPA-OR; UNQ6308	3-hydroxybutyrate dehydrogenase 2
TCMBANKGE012495	PECR	DCRRP; HPDHASE; HSA250303; PVIARL; SDR29C1; TERP	peroxisomal trans-2-enoyl-CoA reductase
TCMBANKGE012776	DECR2	PDCR; SDR17C1	2,4-dienoyl-CoA reductase 2
TCMBANKGE012786	RDH13	SDR7C3	retinol dehydrogenase 13
TCMBANKGE012862	DHRS4	CR; NRDR; PHCR; PSCD; SCAD-SRL; SDR-SRL; SDR25C1; SDR25C2	dehydrogenase/reductase 4
TCMBANKGE013060	HSD17B8	D6S2245E; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1; dJ1033B10.9	hydroxysteroid 17-beta dehydrogenase 8
TCMBANKGE013304	HSDL2	C9orf99; SDR13C1	hydroxysteroid dehydrogenase like 2
TCMBANKGE013338	CTNNA1	CAP102; MDPT2	catenin alpha 1
TCMBANKGE014135	HSD17B14	DHRS10; SDR47C1; retSDR3	hydroxysteroid 17-beta dehydrogenase 14
TCMBANKGE014269	AKR1C1	2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB	aldo-keto reductase family 1 member C1
TCMBANKGE014938	DHRS2	HEP27; SDR25C1	dehydrogenase/reductase 2