Compound Summary

  Compound Information
TCMBANKIN029312

药名:

melanin

别名:

AKOS030232017; FT-0628190; 6,14-dimethyl-4,12-diazapentacyclo[8.6.1.1;{2,5}.0;{13,17}.0;{9,18}]octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetrone; CHEBI:89634; D0WQ4G; API0003281; CTK8G0775; 8049-97-6; XUMBMVFBXHLACL-UHFFFAOYSA-N; Phaeomelanins; Melanin; 6,14-dimethyl-4,12-diazapentacyclo[8.6.1.1^{2,5}.0^{13,17}.0^{9,18}]octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetrone; GTPL5415; Melanin from Sepia officinalis

分子式:

C18H10N2O4

Smiles:

CC1=C2C3=C(C4=CNC5=C(C(=O)C(=O)C(=C45)C3=CN2)C)C(=O)C1=O

成分:

HBIN034656

OB_score:

26.400369

CAS_id:

8049-97-6

SymMap_id:

SMIT00852

TCMID_id:

13652

TCMSP_id:

MOL013053

PubChem_id:

6325610

   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000390 Crinis Carbonisatus 血余炭 Treatment of hematemesis, epistaxis, hematuria, abnormal uterine bleeding, traumatic bleeding./1. Inhibiting the growth of various pathogenic bacteria2. Shortening the bleeding time , blood clotting time and plasma recalcification time.
TCMBANKHE000895 Hippocampus 海马 Treatment of impotence, enuresis, dyspnea in deficiency syndrome of the kidney, mass in the abdomen, traumatic injuries, external use for carbuncles and boils./Exerting gonadotropic effect, ie., prolonging estruation and increasing the weight of ovary and uterus in female mice and that of prostate, seminal vesicl and musculi levator ani in male mice.
TCMBANKHE006052 Capra hircus, Ovis aries 羊皮 To supplement vacuity, dispel stasis, disperse swelling./Vacuity taxation with emaciation and weakness, painful swelling from knocks and falls, bleeding due to tympanites.
TCMBANKHE006326 Semen Vaccariae 王不留行 1. To invigorate blood and promote menstruation; 2. To promote lactation/Galactostasis, amenorrhea, dysmenorrhea, mammary welling abscess.
TCMBANKHE005110 Lasiosphaera seu Calvatia 马勃 To remove heat from the lung and soothe sore throat, and to arrest bleeding./Cough, aphonia, nosebleed(epistaxis), bleeding due to external injury.
TCMBANKHE008895 Homo sapiens 血余 To dispel stasis and stanch bleeding./Blood ejection, nosebleed(epistaxis), gum hemorrhage, blood dysentery, blood strangury, flooding and spotting.
TCMBANKHE005732 Dalbergia odorifera 降真香 To quicken blood and dissipate stasis, stanch bleeding and settle pain, downbear qi , break foul./Chest and rib-side pain, knocks and falls, bleeding due to external injury, bleeding due to external injury.
TCMBANKHE007004 Semen Myristicae 肉豆蔻 To warm the spleen and stomach and promote the flow of qi , to arrest diarrhea as an astringent./Spleen-stomach vacuity cold, incessant chronic diarrhea, distending pain in stomach duct, reduced food intake with vomiting.
TCMBANKHE003969/YEM-213 Luffa cylindrica|Luffa cylindrica(L.)Roem. 丝瓜籽|丝瓜 丝瓜 云南民族药物志：第二卷 To clear heat, disinhibit water, free stool, expel worms./Edema, stone strangury, lung heat cough, intestinal wind bleeding, hemorrhoids and fistulas, constipation, ascariasis. 阿昌族/傣族/德昂族/景颇族/傈僳族/水族/彝族/藏族
   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000029 GZMB C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT granzyme B
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000137 PLAU ATF; BDPLT5; QPD; UPA; URK; u-PA plasminogen activator, urokinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000872 IGF1R CD221; IGFIR; IGFR; JTK13 insulin like growth factor 1 receptor
TCMBANKGE000881 PLAT T-PA; TPA plasminogen activator, tissue type
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000988 HGF DFNB39; F-TCF; HGFB; HPTA; SF hepatocyte growth factor
TCMBANKGE000992 KLK3 APS; KLK2A1; PSA; hK3 kallikrein related peptidase 3
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001148 VEGFA MVCD1; VEGF; VPF vascular endothelial growth factor A
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1
TCMBANKGE001620 TMPRSS6 IRIDA; MT2 transmembrane serine protease 6
TCMBANKGE001633 PRSS48 ESSPL serine protease 48
TCMBANKGE002055 KLK5 KLK-L2; KLKL2; SCTE kallikrein related peptidase 5
TCMBANKGE002353 TPSD1 MCP7-LIKE; MCP7L1; MMCP-7L tryptase delta 1
TCMBANKGE002441 TMPRSS7 - transmembrane serine protease 7
TCMBANKGE002490 AZU1 AZAMP; AZU; CAP37; HBP; HUMAZUR; NAZC; hHBP azurocidin 1
TCMBANKGE002588 KLK1 KLKR; Klk6; hK1 kallikrein 1
TCMBANKGE002732 GZMA CTLA3; HFSP granzyme A
TCMBANKGE003132 TMPRSS11D ASP; HAT transmembrane serine protease 11D
TCMBANKGE003215 PRSS21 ESP-1; ESP1; TEST1; TESTISIN serine protease 21
TCMBANKGE003236 KLK13 KLK-L4; KLKL4 kallikrein related peptidase 13
TCMBANKGE003256 TMPRSS11A ECRG1; HATL1; HESP transmembrane serine protease 11A
TCMBANKGE003301 CORIN ATC2; CRN; Lrp4; PEE5; TMPRSS10 corin, serine peptidase
TCMBANKGE003643 F7 SPCA coagulation factor VII
TCMBANKGE003693 GZMH CCP-X; CGL-2; CSP-C; CTLA1; CTSGL2 granzyme H
TCMBANKGE003704 PRSS40A TISP43 serine protease 40A (pseudogene)
TCMBANKGE003820 PRSS42P PRSS42; TESSP2 serine protease 42, pseudogene
TCMBANKGE004219 CTSG CATG; CG cathepsin G
TCMBANKGE004241 F11 FXI; PTA coagulation factor XI
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE004684 KLK6 Bssp; Klk7; PRSS18; PRSS9; SP59; hK6 kallikrein related peptidase 6
TCMBANKGE005316 TMPRSS4 CAPH2; MT-SP2; TMPRSS3 transmembrane serine protease 4
TCMBANKGE005358 CTRB1 CTRB chymotrypsinogen B1
TCMBANKGE005516 PRSS58 PRSS1; TRY1; TRYX3; UNQ2540 serine protease 58
TCMBANKGE006000 TMPRSS9 - transmembrane serine protease 9
TCMBANKGE006002 F12 HAE3; HAEX; HAF coagulation factor XII
TCMBANKGE006077 KLK2 KLK2A2; hGK-1; hK2 kallikrein related peptidase 2
TCMBANKGE006352 PROC APC; PC; PROC1; THPH3; THPH4 protein C, inactivator of coagulation factors Va and VIIIa
TCMBANKGE006354 PRSS8 CAP1; PROSTASIN serine protease 8
TCMBANKGE006400 PLG - plasminogen
TCMBANKGE006484 PRSS36 - serine protease 36
TCMBANKGE006690 PRSS12 BSSP-3; BSSP3; MRT1 serine protease 12
TCMBANKGE006803 OVCH1 OVCH ovochymase 1
TCMBANKGE006804 TMPRSS12 CT151 transmembrane serine protease 12
TCMBANKGE006808 CMA1 CYH; MCT1; chymase chymase 1
TCMBANKGE006928 CTRL CTRL1 chymotrypsin like
TCMBANKGE006961 F2 PT; RPRGL2; THPH1 coagulation factor II, thrombin
TCMBANKGE007218 PRSS53 POL3S; UNQ308 serine protease 53
TCMBANKGE007414 KLKB1 KLK3; PKK; PKKD; PPK kallikrein B1
TCMBANKGE007503 HABP2 FSAP; HABP; HGFAL; NMTC5; PHBP hyaluronan binding protein 2
TCMBANKGE007858 GZMK TRYP2 granzyme K
TCMBANKGE008068 PRTN3 ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3 proteinase 3
TCMBANKGE008270 MST1 D3F15S2; DNF15S2; HGFL; MSP; NF15S2 macrophage stimulating 1
TCMBANKGE008426 CTRB2 - chymotrypsinogen B2
TCMBANKGE008519 CTRC CLCR; ELA4 chymotrypsin C
TCMBANKGE008575 C1RL C1RL1; C1RLP; C1r-LP; CLSPa complement C1r subcomponent like
TCMBANKGE008637 PRSS45P PRSS45; TESPL; TESSP5 serine protease 45, pseudogene
TCMBANKGE008707 KLK12 KLK-L5; KLKL5 kallikrein related peptidase 12
TCMBANKGE008718 PRSS3 MTG; PRSS4; T9; TRY3; TRY4 serine protease 3
TCMBANKGE008884 PRSS37 TRYX2 serine protease 37
TCMBANKGE009010 HPN TMPRSS1 hepsin
TCMBANKGE009022 KLK9 KLK-L3; KLKL3 kallikrein related peptidase 9
TCMBANKGE009092 F9 F9 p22; FIX; HEMB; P19; PTC; THPH8 coagulation factor IX
TCMBANKGE009097 TMPRSS13 MSP; MSPL; MSPS; TMPRSS11 transmembrane serine protease 13
TCMBANKGE009251 PRSS50 CT20; TSP50 serine protease 50
TCMBANKGE009310 CELA2A AOMS4; ELA2A; PE-1 chymotrypsin like elastase 2A
TCMBANKGE009342 F10 FX; FXA coagulation factor X
TCMBANKGE009495 MASP1 3MC1; CRARF; CRARF1; MAP1; MASP; MASP3; MAp44; PRSS5; RaRF mannan binding lectin serine peptidase 1
TCMBANKGE009570 LPA AK38; APOA; LP lipoprotein(a)
TCMBANKGE009584 TMPRSS11F HATL4 transmembrane serine protease 11F
TCMBANKGE009683 KLK15 ACO; HSRNASPH kallikrein related peptidase 15
TCMBANKGE009778 KLK11 PRSS20; TLSP kallikrein related peptidase 11
TCMBANKGE009806 PRSS55 CT153; T-SP1; TSP1; UNQ9391 serine protease 55
TCMBANKGE009831 PRSS54 CT67; KLKBL4 serine protease 54
TCMBANKGE009933 TPSAB1 TPS1; TPS2; TPSB1; TPSB2; Tryptase-2 tryptase alpha/beta 1
TCMBANKGE010125 ACR - acrosin
TCMBANKGE010345 KLK14 KLK-L6 kallikrein related peptidase 14
TCMBANKGE010396 TMPRSS11E DESC1; TMPRSS11E2 transmembrane serine protease 11E
TCMBANKGE010469 C1S EDSPD2 complement C1s
TCMBANKGE010510 PRSS27 CAPH2; MPN serine protease 27
TCMBANKGE010582 MASP2 MAP19; MASP-2; MASP1P1; sMAP mannan binding lectin serine peptidase 2
TCMBANKGE010708 PRSS33 EOS serine protease 33
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE011169 PRSS38 MPN2 serine protease 38
TCMBANKGE011287 CFB AHUS4; ARMD14; BF; BFD; CFAB; CFBD; FB; FBI12; GBG; H2-Bf; PBF2 complement factor B
TCMBANKGE011859 CFI AHUS3; ARMD13; C3BINA; C3b-INA; FI; IF; KAF complement factor I
TCMBANKGE011897 CELA3B CBPP; ELA3B chymotrypsin like elastase 3B
TCMBANKGE011999 PEPD PROLIDASE peptidase D
TCMBANKGE012118 TMPRSS2 PRSS10 transmembrane serine protease 2
TCMBANKGE012272 CELA1 ELA1 chymotrypsin like elastase 1
TCMBANKGE012558 TMPRSS11B HATL5 transmembrane serine protease 11B
TCMBANKGE012618 PRSS57 NSP4; PRSSL1; UNQ782 serine protease 57
TCMBANKGE012788 PRSS22 BSSP-4; SP001LA; hBSSP-4 serine protease 22
TCMBANKGE013170 ELANE ELA2; GE; HLE; HNE; NE; PMN-E; SCN1 elastase, neutrophil expressed
TCMBANKGE013184 HP BP; HP2ALPHA2; HPA1S haptoglobin
TCMBANKGE013331 TMPRSS15 ENTK; PRSS7 transmembrane serine protease 15
TCMBANKGE013347 PROZ PZ protein Z, vitamin K dependent plasma glycoprotein
TCMBANKGE013510 KLK4 AI2A1; ARM1; EMSP; EMSP1; KLK-L1; PRSS17; PSTS; kallikrein kallikrein related peptidase 4
TCMBANKGE013570 CELA3A ELA3; ELA3A chymotrypsin like elastase 3A
TCMBANKGE013596 HPR A-259H10.2; HP haptoglobin-related protein
TCMBANKGE013732 PRSS46P PRSS46; TESSP6 serine protease 46, pseudogene
TCMBANKGE014037 GZMM LMET1; MET1 granzyme M
TCMBANKGE014164 KLK8 HNP; NP; NRPN; PRSS19; TADG14 kallikrein related peptidase 8
TCMBANKGE014271 TMPRSS3 DFNB10; DFNB8; ECHOS1; TADG12 transmembrane serine protease 3
TCMBANKGE014504 ST14 ARCI11; HAI; MT-SP1; MTSP1; PRSS14; SNC19; TADG15; TMPRSS14 ST14 transmembrane serine protease matriptase
TCMBANKGE014638 CELA2B ELA2B chymotrypsin like elastase 2B
TCMBANKGE014773 TMPRSS5 SPINESIN transmembrane serine protease 5
TCMBANKGE014839 TPSG1 PRSS31; TMT; trpA tryptase gamma 1
TCMBANKGE014859 HGFAC HGFA HGF activator
TCMBANKGE014925 C2 ARMD14; CO2 complement C2
TCMBANKGE014974 KLK7 PRSS6; SCCE; hK7 kallikrein related peptidase 7
TCMBANKGE014999 CFD ADIPSIN; ADN; DF; PFD complement factor D
TCMBANKGE015011 KLK10 NES1; PRSSL1 kallikrein related peptidase 10

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