Compound Summary

  Compound Information

TCMBANKIN031306

药名:	kainic acid
别名:	alpha- Kainic acid; K0250_SIGMA; Kainic acid monohydrate; (2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid hydrate; SCHEMBL6081964; (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid; InChI=1/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s; L-proline, 3-(carboxymethyl)-4-(1-methylethenyl)-, (3S,4S)-; UPCMLD-DP146:001; D02546; Kainic acid hydrate; C12819; I519JC63XY; MLS001074661; NCGC00024504-05; 4-22-00-01523 (Beilstein Handbook Reference); rel-(3R,4R)-3-(carboxymethyl)-4-isopropenyl-D-proline; NSC136038; EU-0100656; (2S,3S,4R)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid; NCGC00024504-03; Kainic acid [INN:JAN]; DTXSID50206732; 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, monohydrate, (2S-(2alpha,3beta,4beta))-; KAINIC ACID 2-CARBOXY-3-CARBOXYMETHYL-4-ISOPROPENYLPYRROLIDINE; (-)-Kainic acid hydrate; (2S,3S,4S)-3-(carboxymethyl)-4-isopropenyl-2-pyrrolidinecarboxylic acid; 2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine; SC-66129; 2-Carboxy-4-isopropenyl-3-pyrrolidineacetic acid; SR-01000075454-9; (2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-yl-pyrrolidine-2-carboxylic acid; BRN 0086660; NSC 136038; 3-Pyrrolidineacetic acid, 2-carboxy-4-isopropenyl-; Lopac0_000656; Acide kainique [INN-French]; MolPort-009-018-775; 58002-62-3; L-alpha-Kainic acid; Kainic acid monohydrate, >=98% (HPLC), from Digenea simplex; 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, hydrate (1:1), (2S,3S,4S)-; nchembio881-comp3; Digenin; HMS3649I10; 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2-alpha,3-beta,4-beta))- (9CI); Digenic acid; NCGC00024504-06; UPCMLD-DP146:002; Acido kainico [INN-Spanish]; BPBio1_001306; C10H15NO4.H2O; Kainic acid hydrate [JAN]; (2S,3S,4S)-3-(carboxymethyl)-4-isopropenyl-proline; 487-79-6; Kainic acid monohydrate, >=99% (TLC); (2S,3S,4S)-3-(carboxymethyl)-4-isopropenyl-pyrrolidine-2-carboxylic acid; 1810AH; Kainate; SMR000471885; Kainic Acid, Natural; UNII-I519JC63XY; 2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid; Acidum kainicum [INN-Latin]; Kainic acid hydrate (JP17); 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-; KAINIC ACID; Digenin (TN); (2S,3S,4S)-3-(Carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid; Helminal; Biomol-NT_000217
分子式:	C10H15NO4
Smiles:	CC(=C)C1CNC(C1CC(=O)O)C(=O)O
成分:	HBIN031993
OB_score:	63.38989
CAS_id:	487-79-6
SymMap_id:	SMIT00857
TCMID_id:	23082
TCMSP_id:	MOL013326
PubChem_id:	10255

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004490	Digenea simplex	海人草			To expel roundworm./Ascariasis.
TCMBANKHE006932	Caulis Piperis Kadsurae;Caulis Piperis futokadsurae	海风藤			To relieve rheumatic conditions./Wind-cold-damp impediment, aching sinews in limb joints, hypertonicity of sinews and vessels.
TCMBANKHE006303	Caloglossa leprieurii	鹧鸪菜			To expel roundworm./Ascariasis.
TCMBANKHE008131	Herba Abri	鸡骨草			To remove toxic heat, and to relieve the depressed liver and alleviate pain./Icterohepatitis, stomachache, wind-damp bone pain, stasis pain from knocks and falls, mammary welling abscess.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000029	GZMB	C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT	granzyme B
TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000075	IL1RN	DIRA; ICIL-1RA; IL-1RN; IL-1ra; IL-1ra3; IL1F3; IL1RA; IRAP; MVCD4	interleukin 1 receptor antagonist
TCMBANKGE000219	CCR5	CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22	C-C motif chemokine receptor 5
TCMBANKGE000221	GRIA2	GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B	glutamate ionotropic receptor AMPA type subunit 2
TCMBANKGE000236	BDNF	ANON2; BULN2	brain derived neurotrophic factor
TCMBANKGE000271	APOE	AD2; APO-E; ApoE4; LDLCQ5; LPG	apolipoprotein E
TCMBANKGE000274	CCL2	GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF	C-C motif chemokine ligand 2
TCMBANKGE000414	CYP19A1	ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM	cytochrome P450 family 19 subfamily A member 1
TCMBANKGE000468	CTSB	APPS; CPSB; RECEUP	cathepsin B
TCMBANKGE000545	CXCL2	CINC-2a; GRO2; GROb; MGSA-b; MIP-2a; MIP2; MIP2A; SCYB2	C-X-C motif chemokine ligand 2
TCMBANKGE000585	BCL2L11	BAM; BIM; BOD	BCL2 like 11
TCMBANKGE000745	BAG3	BAG-3; BIS; CAIR-1; MFM6	BAG cochaperone 3
TCMBANKGE000759	MAP1LC3B	ATG8F; LC3B; MAP1A/1BLC3; MAP1LC3B-a	microtubule associated protein 1 light chain 3 beta
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE001103	MDM2	ACTFS; HDMX; LSKB; hdm2	MDM2 proto-oncogene
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001169	BCL2L1	BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52	BCL2 like 1
TCMBANKGE001177	TP53	BCC7; BMFS5; LFS1; P53; TRP53	tumor protein p53
TCMBANKGE001179	SMAD2	JV18; JV18-1; MADH2; MADR2; hMAD-2; hSMAD2	SMAD family member 2
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE001191	GRIA1	GLUH1; GLUR1; GLURA; GluA1; HBGR1	glutamate ionotropic receptor AMPA type subunit 1
TCMBANKGE001193	GDNF	ATF; ATF1; ATF2; HFB1-GDNF; HSCR3	glial cell derived neurotrophic factor
TCMBANKGE001393	NRCAM	-	neuronal cell adhesion molecule
TCMBANKGE001816	HRH1	H1-R; H1R; HH1R; hisH1	histamine receptor H1
TCMBANKGE002133	HRK	DP5; HARAKIRI	harakiri, BCL2 interacting protein
TCMBANKGE002494	PENK	PE; PENK-A	proenkephalin
TCMBANKGE003089	ITPKA	IP3-3KA; IP3KA	inositol-trisphosphate 3-kinase A
TCMBANKGE005458	MT3	GIF; GIFB; GRIF; ZnMT3	metallothionein 3
TCMBANKGE005560	DBT	BCATE2; BCKAD-E2; BCKADE2; BCOADC-E2; E2; E2B	dihydrolipoamide branched chain transacylase E2
TCMBANKGE005712	DNAJB1	HSPF1; Hdj1; Hsp40; RSPH16B; Sis1	DnaJ heat shock protein family (Hsp40) member B1
TCMBANKGE006565	NPY	PYY4	neuropeptide Y
TCMBANKGE006643	YWHAZ	14-3-3-zeta; HEL-S-3; HEL-S-93; HEL4; KCIP-1; POPCHAS; YWHAD	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
TCMBANKGE006736	BCL2L2	BCL-W; BCL2-L-2; BCLW; PPP1R51	BCL2 like 2
TCMBANKGE008206	NTF3	HDNF; NGF-2; NGF2; NT-3; NT3	neurotrophin 3
TCMBANKGE009562	C5AR1	C5A; C5AR; C5R1; CD88	complement C5a receptor 1
TCMBANKGE010521	SLC5A11	KST1; RKST1; SGLT6; SMIT2	solute carrier family 5 member 11
TCMBANKGE010692	KAT5	ESA1; HTATIP; HTATIP1; PLIP; TIP; TIP60; ZC2HC5; cPLA2	lysine acetyltransferase 5
TCMBANKGE010804	PRKAG2	AAKG; AAKG2; CMH6; H91620p; WPWS	protein kinase AMP-activated non-catalytic subunit gamma 2
TCMBANKGE010821	MAP1A	MAP1L; MTAP1A	microtubule associated protein 1A
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE013016	LIPG	EDL; EL; PRO719	lipase G, endothelial type
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1