Compound Summary

  Compound Information

TCMBANKIN031942

药名:	questinol
别名:	1,6-Dihydroxy-3-hydroxymethyl-8-methoxyanthraquinone; 35688-09-6; omega-Hydroxymethylemodin; DTXSID50189192; Questinol_120239; Questinol; 9,10-Anthracenedione, 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxy-; 1,6-Dihydroxy-3-(hydroxymethyl)-8-methoxy-9,10-anthracenedione; SCHEMBL16226232; 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxy-9,10-dihydroanthracene-9,10-dione; CHEBI:81349; C17811; AC1L3VJY; 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione; 1-Hydroxy-3-(hydroxymethyl)-6-hydroxy-8-methoxy-9,10-anthraquinone; 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxy-anthracene-9,10-dione; 1,6-dihydroxy-8-methoxy-3-methylol-9,10-anthraquinone
分子式:	C16H12O6
Smiles:	COC1=CC(=CC2=C1C(=O)C3=C(C2=O)C=C(C=C3O)CO)O
成分:	HBIN041738
SymMap_id:	SMIT01591;SMIT13963
TCMID_id:	18402
TCMSP_id:	MOL013293
PubChem_id:	147621

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003822	Rumex patientia	牛西西			To clear heat and resolve toxin, stanch bleeding and disperse swelling, free stool and kill worms./Blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, red and white vaginal discharge, purpura, dysentery, hepatitis, constipation, inhibited urination, swelling toxin of welling abscess and sore, scab and lichen, knocks and falls, burns and scalds.
TCMBANKHE004026	Polygonum multiflorum;Caulis Polygoni Multiflori	夜交藤;首乌藤			To nourish heart and quiet spirit, dispel wind and free network vessels.;Treatment of insomnia, dream-disturbed sleep, general aching in blood deficiency, rheumatic arthralgia, external use for itching./Insomnia, frequent dreaming, anemia and generalized pain, muscle numbness, wind-damp impediment pain, wind papule itching.;1. Decreasing the level of blood lipids and inhibiting the formation of atherosclerosis.2. Oral admintration of its decoction increases the level of blood sugar in rabbits.
TCMBANKHE008555	Polygonum multiflorum	何首乌			To lower cholesterol, enrich yin and nourish blood, moisten intestines and free stool, interrupt malaria, dispel wind, resolve toxin./Backache, neurasthenia, hyperlipemia, neurosis, insomnia, dizziness due to anemia, palpitation, limp aching lumbus and knees due to liver kidney yin vacuity, premature graying in beard and hair, tinnitus, emission, intestinal dry and constipation, enduring malaria, wind papule itching, sore and welling abscess, scrofula, hemorrhoids.
TCMBANKHE004697	Radix Kansui	甘遂			To cause drastic purgation and expel the retained water./Edema, ascites, flowing rheum in chest, concretion conglomeration accumulation and gathering, epilepsy, cough and asthma, urinar y and fecal stoppage.
TCMBANKHE006281	Polygonum multiflorum	夜交藤			To nourish heart and quiet spirit, dispel wind and free network vessels./Insomnia, frequent dreaming, anemia and generalized pain, muscle numbness, wind-damp impediment pain, wind papule itching.
TCMBANKHE005418/YNS-102	Rhizoma Polygoni cuspidati|Polygonum cuspidatum Sieb.et Zucc.	虎杖	虎杖叶	云南药材标准：第一册	平肝潜阳，祛痰息风。用于肝阳上亢，血压偏高，头晕头昏|To dispel wind and damp, to eliminate blood stasis and alleviate pain, to relieve cough, and to resolve phlegm./Hyperlipemia, impediment pain in joints, damp-heat jaundice, toxic jaundice, child jaundice, amenorrhea, hepatitis, appendicitis, candida vaginitis, concretion and conglomeration, cough with profuse phlegm, burns and scalds, knocks and falls, swelling toxin of welling abscess and sore.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE003643	F7	SPCA	coagulation factor VII
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1