Compound Summary


  Compound Information

药名:

Quinicine

别名:

quinicine

分子式:

C20H24N2O2

Smiles:

COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O

成分:

HBIN041752

OB_score:

75.443182

CAS_id:

52211-63-9

SymMap_id:

SMIT12024;SMIT17408

TCMID_id:

18407

TCMSP_id:

MOL011072

PubChem_id:

441074


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003389 Cinchona ledgeriana To interrupt malaria and abate fever, resolve liquor and arouse spleen./Malaria, externally contracted ardent fever, drunkenness.
TCMBANKHE003843 Citrus limon 柠檬 To engender liquid and allay thirst, dispel summerheat, quiet fetus./Stomach heat fluid damage, summerheat stroke with vexation and thirst, inappetence, glomus distention in stomach duct and abdomen, lung heat dry cough, vomiting in pregnancy.
TCMBANKHE003986 苦丁茶 Common cold, summerheat stroke with fever, jaundice, acute gastroenteritis, bacillary dysentery, sore and boil.
TCMBANKHE006505 Semen Lablab Album 白扁豆 To invigorate the spleen and remove damp, paticularly the summer damp.Semen Lablab Album (stir-fried) To invigorate the spleen and remove damp./Treatment of weakness of the spleen and stomach with loss of appetite and loose bowels, excessive leukorrhea, vomiting, diarrhea, distress in the chest and distension in the abdomen caused by summer-damp.Semen Lablab Album (stir-fried) Diarrhea and excess
TCMBANKHE007068 Eucalyptus citriodora 柠檬桉叶 To dissipate wind and eliminate damp, fortify stomach and relieve pain, resolve toxin and relieve itch./Wind-cold common cold, wind-damp bone pain, qi stagnation stomachache, food accumulation, sand distention and vomiting diarrhea, dysentery, asthma, malaria, sore and boil, wind papules, eczema, intractable lichen, burns and scalds.
TCMBANKHE005221 Semen Ginkgo 白果 1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE005431 Flos Rosae Rugosae 玫瑰花 To relieve stagnation of qi, regulate blood circulation, and to arrest pain./Liver stomach qi pain, reduced food intake with nausea and vomiting, menstrual disorder, painful wound from knocks and falls.
TCMBANKHE008354 Semen Ginkgo 白果 1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE008006 Urtica dioica 异株荨麻 See Urtica cannabina./See Urtica cannabina.
TCMBANKHE007150/YEM-237/XU-798 Helianthus annuus|Helianthus annuus L. 向日葵籽|向日葵 向日葵 云南民族药物志:第二卷|云南省昆明市呈贡区 To outthrust papules, check dysentery, outthrust welling abscess and pus./Blood dysentery, welling abscess with pus swelling. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE007824/YEM-258/XU-654 Ficus carica|Ficus carica L.|Ficus carica Linn. 无花果 无花果 云南民族药物志:第二卷|云南省曲靖市宣威市 To clear heat and engender liquid, fortify spleen and promote digestion, resolve toxin and disperse swelling./Swelling pain in throat, dry cough with hoarseness, scant breast milk, intestinal heat and constipation, inappetence, indigestion, diarrhea, dysentery, swollen welling abscess, lichen. 傣族/哈尼族/苗族/佤族
TCMBANKHE005504/YEM-314 Vitis vinifera|Vitis vinifera L. 葡萄藤叶|葡萄 葡萄 云南民族药物志:第二卷 To dispel wind and eliminate damp, disinhibit water and disperse edema, resolve toxin./Edema, inhibited urination, red eyes, swollen welling abscess, wind-damp impediment pain. 傣族/藏族
TCMBANKHE004332/YEM-378/XU-663 Foeniculum vulgare|Foeniculum vulgare Mill. 茴香茎叶|茴香 小茴香 云南民族药物志:第二卷|云南省玉溪市澄江县 To expel wind, normalize qi, relieve pain./Sand qi, mounting qi, swollen welling abscess. 白族/布依族/傣族/傈僳族/纳西族/彝族/藏族/壮族
TCMBANKHE005293/YEM-407 Prunus persica|Prunus persica(L.)Batsch 桃叶|桃 桃仁 云南民族药物志:第二卷 To dispel wind and clear heat, dry damp and resolve toxin, kill worms./Externally contracted wind evil, head wind, headache, wind impediment, eczema, swollen welling abscess and sores, lichen sore, malaria, trichomoniasis. 阿昌族/白族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/水族/佤族/瑶族/彝族/藏族/壮族
TCMBANKHE006576/YEM-61/XU-569 Fructus Chebulae|Terminalia chebula Retz.|Terminalia chebula var. tomentella 诃子|微毛诃子 诃子 云南民族药物志:第一卷|云南省临沧市永德县 To check diarrhea and chronic cough, and to soothe the sore throat./Chronic diarrhea and dysentery, hematochezia, prolapse of rectum, cough and asthma due to lung vacuity, incessant cough, aphonia due to throat pain. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE007072/YEM-61/XU-569 Terminalia chebula|Terminalia chebula Retz.|Terminalia chebula var. tomentella 诃子叶|诃子|微毛诃子 诃子 云南民族药物志:第一卷|云南省临沧市永德县 To precipitate qi and disperse phlegm, allay thirst, check dysentery./Enduring cough and aphonia, chronic diarrhea, chronic dysentery. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE007344/YEM-665 Poria; Sclerotium Poriae Cocos; Sclerotium Poriae Cocos|Poria cocos(Schw.)Wolf 茯苓; 云苓|茯苓 茯苓 云南民族药物志:第四卷 To cause diuresis, to invigorate the spleen function, and to calm the mind.; Treatment of edema with oliguria, dizziness and palpitation caused by retained fluid, diminished function of the spleen marked by anorexia, loose stools or diarrhea, restlessness and insomnia./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea.; 1. An active component pachyman promotes macrophage phagocytosis in mice, and enhances lymphocyte-blastogensis rate in vitro.2. Preventing the formation of gastric ulcer under stress in rats3. Diuretic and liver-protective. 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE004574/YEM-665 Poria|Poria cocos(Schw.)Wolf 茯苓 茯苓 云南民族药物志:第四卷 To cause diuresis, to invigorate the spleen function, and to calm the mind./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea. 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000121 KCNH2 ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1 potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE000965 CHRNA7 CHRNA7-2; NACHRA7 cholinergic receptor nicotinic alpha 7 subunit
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008124 ADRA2B ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR; FAME2; alpha-2BAR adrenoceptor alpha 2B
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE011923 CHRM4 HM4; M4R cholinergic receptor muscarinic 4
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1
TCMBANKGE014790 ADRB1 ADRB1R; B1AR; BETA1AR; FNSS2; RHR adrenoceptor beta 1