Compound Summary


  Compound Information

药名:

Decussine

别名:

decussine; AC1L4FZX; CHEMBL454319; 75375-52-9; DTXSID70226336; 17,13-Dimethyl-5,6-dihydro-7H,13H-pyrido(4',3':6,5)azepino(1,2,3-l,m)-beta-carboline; LS-154686; (R)-1,8-Dimethyl-1,2,3,8-tetrahydro-1,7b,10-triazabenzo(5,6)cyclohepta(1,2,3-jk)fluorene; BRN 5603747; 1,7b,10-Triazabenzo(5,6)cyclohepta(1,2,3-jk)fluorene, 1,2,3,8-tetrahydro-1,8-dimethyl-, (R)-; AC1Q29PP; (20R)-11,20-DIMETHYL-1,11,17-TRIAZAPENTACYCLO[10.8.1.0(2),?.0?,(2)(1).0(1)?,(1)?]HENICOSA-2(7),3,5,8(21),12,14(19),15,17-OCTAENE

分子式:

C20H19N3

Smiles:

CC1C2=C(C=CN=C2)C=C3C4=C(CCN3C)C5=CC=CC=C5N14

成分:

HBIN022941

OB_score:

39.829972

CAS_id:

75375-52-9

SymMap_id:

SMIT13779;SMIT14936

TCMID_id:

4863

TCMSP_id:

MOL013081

PubChem_id:

156336


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000345 Strychnos decussata 对生玛茜
TCMBANKHE001350 Seseli grandivittatum
TCMBANKHE008512 radix Peucedani 前胡 To dispel wind and remove heat, and to relieve cough and resolve phlegm ./Cough, externally contracted wind-heat, lung heat phlegm depression, cough and asthma with abundant phlegm, sticky phlegm, retching counterflow and reduced food intake, fullness and oppression in chest and diaphragm.
TCMBANKHE007994 Herba Humuli Scandentis;Rhaponticum carthamoides 葎草 1. Diurectic. 2. Bacteriostatic. Flower and fruit inhibit the growth of Bacillus tuberculosis and its alcoholic infusion of stemsand leaves inhibits that of gram-positive bacteria in vitro. ;To boost qi and fortify spleen, quiet spirit./Tuberculosis, cystitis, mastitis, tonsillitis, lung heat cough, pulmonary welling abscess, vacuity heat with vexation and thirst, heat strangury, edema, inhibited urination, damp-heat diarrhea dysentery, heat toxin sores, itchy skin.

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE009294 HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 5-hydroxytryptamine receptor 3A