Compound Summary


  Compound Information

药名:

acacetin

别名:

Linarigenin; KBio2_000595; AIDS014771; SPECTRUM200499; 480-44-4; Acaceztin; 4'-Methoxy-5,7-dihydroxyflavone; Akatsetin; A827453; KBio1_000878; 5,7-Dioxy-4'-methoxyflavone; Apigenin 4'-dimethyl ether; NSC76061; CHEBI:15335; Prestwick1_000695; Spectrum_000135; 5,7-dihydroxy-2-(4-methoxyphenyl)-4-chromenone; NINDS_000878; 00017_FLUKA; ZINC00005600; Acacetin; AIDS-014771; WLN: T66 BO EVJ CR DO1& GQ IQ; Acacetine; IDI1_000878; Flavone, 5,7-dihydroxy-4'-methoxy- (8CI); 5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone; Prestwick0_000695; NSC 76061; Spectrum5_000930; SPBio_002770; CHEBI:57284; KBioSS_000595; Prestwick_49; NCGC00095213-03; BCBcMAP01_000082; NCGC00016458-01; KBio2_003163; BPBio1_000935; Prestwick2_000695; KBio2_005731; ACAETIN; SMP1_000001; Apigenin 4'-methyl ether; DivK1c_000878; 7-hydroxy-2-(4-methoxyphenyl)-4-oxo-1-benzopyran-5-olate; Prestwick3_000695; 5,7-dihydroxy-2-(4-methoxyphenyl)chromone; 5,7-Dihydroxy-4'-methoxyflavone; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-methoxyphenyl)-; 5,7-dihydroxy-2-(4-methoxyphenyl)chromen-4-one; BRN 0277879; Flavone, 5,7-dihydroxy-4'-methoxy-; 2-(4-methoxyphenyl)-7-oxidanyl-4-oxidanylidene-chromen-5-olate; C01470; CAS-480-44-4; Buddleoflavonol; NCGC00095213-01; Linarisenin; EINECS 207-552-3; 5-18-04-00575 (Beilstein Handbook Reference); NCGC00095213-02; ST066889; BSPBio_000849; Apisenin 4'-methyl ether; acacetin ; 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-olate; 4'-Methoxyapigenin; 5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one

分子式:

C16H12O5

Smiles:

c1([H])c(OC(c2c([H])c([H])c(OC([H])([H])[H])c([H])c2[H])=C([H])C3=O)c3c(O[H])c([H])c1O[H]

成分:

HBIN014294

OB_score:

34.973573

CAS_id:

480-44-4

SymMap_id:

SMIT00117

TCMID_id:

56;35396

TCMSP_id:

MOL001689

PubChem_id:

5280442


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004471 Humulus lupulus 啤酒花 To fortify stomach and disperse food, disinhibit urine and quiet spirit, eliminate inflammation./Indigestion, abdominal distention, edema, cystitis, tuberculosis, cough, insomnia, leprosy.
TCMBANKHE001767 羊耳朵叶
TCMBANKHE001804 白菊花根
TCMBANKHE002688 Semen armeniacae amarum 苦杏仁 To relieve cough and asthma, and to relax bowels./Treatment of cough and asthma accompanied by stuffiness in the chest and profuse expectoration, constipation due to deficiency of blood and fluid.
TCMBANKHE003426 Fructus Leonuri 茺蔚子 To activate blood circulation and regulate menstruation, to subdue hyperactivity of the liver, and to clear the eye of opacity./Treatment of menstrual disorders, amenorrhea, hysmenorrhea, inflammation of the eye with formation of corneal opacity, dizziness and headache.
TCMBANKHE003463 荆芥穗
TCMBANKHE003718 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE007156 Herba Patriniae 败酱草 1. To eliminate heat and toxic material, relieve abscess and promote pus drainage. 2. To remove blood stasis and alleviate pain/1. Two active components, patrinene and isopatrinene, possess sedative effect. 2. To promote regeneration of hepatic cells and portal circulation, protect hepatic cells from degernation and improve hepatic function.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003940 Herba Elsholtziae;Haichow Elsholtzia;Mosla chinensis 香薷 1. To promote diaphoresis and release the exterior; 2. To resolve dampness and harmonize the spleen and stomach; 3. To promote water metabolism and release edema/Fever, aversion of cold, headache, absence of sweating, abdominal pain, vomiting and diarrhea, edema and inhibited urination, beriberi.
TCMBANKHE003943 Herba Cirsii Japonici;Radix Cirsii Japonici;Herba seu Radix Cirsii japonici 大蓟 To arrest bleeding by reducing heat in the blood, to remove blood stasis, and to promote the subsidence of swelling.;Treatment of epistaxis, spitting of blood, hematuria, hematochezia, abnormal uterine bleeding, traumatic bleeding, carbuncles and sores./1. Its decoction can lower blood pressure2. Inhibiting the growth of (a)-streptococcus3. Shortening the bleeding time.4. Anti-inflammatory5. Diuretic.
TCMBANKHE003967 Radix Platycodi 桔梗 To relieve cought, to soothe sore throat, and to promote expectoration and discharge of pus./Cough with profuse phlegm, swelling pain in throat, pulmonary welling abscess with hacking of pus and blood, fullness in chest and rib-side pain, dysentery, dribbling urinary block.
TCMBANKHE005793 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE004603 Chrysanthemum indicum 野菊 To clear heat and resolve toxin./Common cold, trachitis, hepatitis, hypertension, dysentery, swollen welling abscess, clove sore, red eyes and distending pain, scrofula, eczema.
TCMBANKHE008626 Cortex Lycii Radicis 地骨皮 To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung./1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect.
TCMBANKHE004907 连钱草 Treatment of acute urinary infection, urolithiasis, acute jaundice, painful swelling in sores and carbuncies, traumatic injuries.
TCMBANKHE005071 Herba Visci 槲寄生 To relieve rheumatic conditions, to replenish the liver and the kidney, to strengthen the tendons and the bones, and to prevent abortion./Hypertension, cerebral and cardiovascular diseases, wind-damp impediment pain, limp aching lumbus and knees, stirring fetus in pregnancy.
TCMBANKHE005269 Flos Chrysanthemi Indici 野菊花 To remove toxic heat./Hypertension, headache and dizziness, insomnia, common cold, influenza, meningitis, swollen welling abscess and clove sores, red eyes with gall.
TCMBANKHE008081 herba ecliptae 墨旱莲 To replenish the liver and the kidney, and to arrest bleeding by removing heat from blood./Tooth mobilizing, premature graying in beard and hair, dizziness and tinnitus, limp aching lumbus and knees, yin vacuity blood heat, hemoptysis, blood ejection, duodenal bleeding, nosebleed(epistaxis), hematuria, blood dysentery, flooding and spotting, bleeding due to external injury, eczema of skin, bleeding of skin, snake bite.
TCMBANKHE007361 Agastache rugosus 藿香 To dispel summerheat and resolve exterior, harmonize stomach and transform damp./Summer common cold, cold-heat headache, glomus and oppression in chest and stomach duct, vomiting and diarrhea, diarrhea in pregnancy, deep-source nasal congestion.
TCMBANKHE005622 鸡矢藤 Wind-damp pain, diarrhea, dysentery, pain in stomach duct and abdomen, qi vacuity edema, heavy head and low food intake, liver spleen enlargement, scrofula, intestinal welling abscess, innominate toxin swelling, knocks and falls.
TCMBANKHE007669 香橼 See Citrus medica .
TCMBANKHE009129 Flos Trollii chinensis 金莲花 For clearing heat and removing toxic substances/Common cold with fever, swelling pain in throat, mouth sore, gum swelling and pain, gum hemorrhage, red eyes with gall, swelling toxin of clove sore, acute periostitis, acute lymphangitis.
TCMBANKHE008647 Apis mellifera ligustica 蜂胶 To eliminate inflammation and relieve pain, moisten skin and engender flesh./Gastric ulcer, oral ulcer, cervical erosion, zoster, psoriasis, skin chap and pain, clavus, wound, carcinoma.
TCMBANKHE008901 Radix Pseudostellariae 太子参 To replenish qi and invigorate the spleen function, and topromote fluid secretion and moisten the lung./Treatment of hypofunction of the spleen with lassitude and anorexia, debility and deficiency of qi and yin marked by spontaneous sweating and thirst during convalescence dry cough due to dryness of the lung.
TCMBANKHE008834 Radix seu Rhizoma rdostachyos 甘松 To regulate the flow of qi and relieve pain, and to invigorate the spleen function./Stomachache, distention fullness in chest and abdomen, headache, hysteria, beriberi.
TCMBANKHE007604 Herba Glechomae Longitubae 金钱草 To remove damp-heat, relieve dysuria, and to promote subsidence of swelling./Increasing biliary secretion.
TCMBANKHE008076 Verbascum lychnites 剪秋罗毛蕊花
TCMBANKHE008212 Herba Cirsii;Herba Cirsii segeti 小蓟 To arrest bleeding by reducing heat in blood, and to remove blood stasis and induce the subsidence of swelling./Coughing of blood, blood ejection, spontaneous external bleeding, hematuria, blood strangury, hematochezia, blood dysentery, flooding and spotting, bleeding due to external injury, swelling toxin of welling abscess and flat abscess.
TCMBANKHE005104/XU-626/XU-651 Robinia pseudoacacia 刺槐花|刺槐 贵州省毕节市金沙县 To stanch bleeding./Precipitate blood of large intestine, hemoptysis, flooding.
TCMBANKHE007867/XU-103 Flos Buddlejae|Buddleja officinalis 密蒙花 云南省昆明市盘龙区 To remove heat, replenish the liver and clear the eye of corneal opacity./Red eyes with gall, delacrimation and photophobia, liver vacuity dim vision, dim vision, malaria.
TCMBANKHE008679/YNS-147/YEM-107/XU-49 Ajuga forrestii|Ajuga forrestii Dies|Ajuga forrestii Diels 痢止蒿 痢止蒿 云南药材标准:第六册|云南民族药物志:第一卷|云南省丽江市玉龙纳西族自治县白沙乡玉水寨丽江高山植物园 清热解毒,利湿通淋,散淤止痛,杀虫。用于肺热咳嗽,咽喉肿痛,牙痛,湿热痢疾,黄疸,热淋,水肿,乳痈,脱疽,痈疮疖肿,跌打损伤,蛔虫症。|To clear heat and resolve toxin, disinhibit water and free strangury, dissipate stasis and relieve pain, expel worms./Lung heat cough, swelling pain in throat, dysentery, jaundice, heat strangury, edema, mastitis, angiitis, swollen sore of welling abscess and boil, knocks and falls, bleeding due to external injury, ascariasis. 白族/傈僳族/藏族
TCMBANKHE005980/YEM-13 herba Menthae;Mentha haplocalyx Briq|Mentha haplocalyx Briq. 薄荷 薄荷 云南民族药物志:第一卷 To dispel wind-heat from the head and eyes, and to promote eruption./Chronic urticaria, infection of upper respiratory tract, sarcoma, wind-heat exterior syndrome, headache and red eyes, swelling pain in throat, non-eruption of measles, dormant papules with pruritus, liver depression and rib-side pain, abdominal distention. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE006668/YEM-19 Aquilaria sinensis|Aquilaria sinensis (Lour.) Spreng. 白木香 沉香 云南民族药物志:第一卷 See Aquilaria agallocha./See Aquilaria agallocha . 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族
TCMBANKHE005548/YEM-255 Pyrrosia sheareri( Baker )Ching 石韦|庐山石韦 庐山石韦 云南民族药物志:第二卷 Heat strangury, blood strangury, stone strangury, urinary stoppage, dripping with inhibited pain, blood ejection, nosebleed(epistaxis), hematuria, flooding and spotting, lung heat cough asthma, urethral stone, urinary tract infection, bleeding. 苗族/彝族/藏族
TCMBANKHE008071/YEM-274 Spora Lygodii|Lygodium japonicum(Thunb.)Sw. 海金沙 海金沙 云南民族药物志:第二卷 To promote diuresis and treat stranguria/Heat strangury, stone strangury, blood strangury, inhibited urination [=dysuria], edema, white turbidity, vaginal discharge, hepatitis, diarrhea, dysentery, common cold with fever, cough and asthma, swelling pain in throat, mouth sore, red eyes with gall, mumps, mammary welling abscess, erysipelas, zoster, burns and scalds, itchy skin, wound swelling from knocks and falls, wind-damp impediment pain, bleeding due to external injury. 阿昌族/白族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/彝族/藏族
TCMBANKHE005387/YNS-267/YEM-782 Elsholtzia bodinieri|Elsholtzia bodinieri Van. 凤尾茶|东紫苏 小山茶 |小山茶 云南药材标准:第一册|云南民族药物志:第四卷 发散解表,清热利湿。用于感冒,咽喉痛,头痛,扁桃腺炎,小儿口腔炎,牙痛,眼结膜炎,肝炎,消化不良|To dissipate exopathogen, rectify qi and harmonize stomach./Common cold, red swollen in throat, red eyes with gall, stomatitis, toothache, hepatitis, indigestion. 拉祜族/彝族
TCMBANKHE006111/YEM-858 Lamiophlomis rotata [Syn. Phlomis rotata ]|Lamiophlomis rotata(Benth.)Kudo 独一味 独一味 云南民族药物志:第五卷 To quicken blood and transform stasis, disperse swelling and relieve pain./Knocks and falls, pain in sinews and bones, swelling pain in joints, dysmenorrhea, flooding and spotting. 阿昌族/傣族/德昂族/景颇族/傈僳族/纳西族/普米族/藏族
TCMBANKHE007056/YEM-9 Herba Lobeliae Chinensis|Lobelia chinensis Lour. 半边莲 半边莲 云南民族药物志:第一卷 To cause diuresis, and to remove toxic heat./Edema, edema and enlarged abdomen, edema in face and foot, swollen welling abscess and clove sores, snake or insect bites. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE004372/YEM-935 Lysimachia paridiformis|Lysimachia paridiformis Franch.var.stenophylla Franch. 重楼排草|狭叶落地梅 狭叶落地梅 云南民族药物志:第五卷 To dispel wind and eliminate damp, quicken blood and relieve pain, relieve cough, resolve toxin./Wind-damp pain, pain in stomach duct and abdomen, cough, knocks and falls, clove sore and swollen boil, poisonous snake bite. 苗族
TCMBANKHE005203/YEM-999/XU-341 Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica 板蓝根|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess. 回族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000063 Atrial Fibrillation disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 21906601

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000241 CASP8 ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 caspase 8
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000294 CDKN1A CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 cyclin dependent kinase inhibitor 1A
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000414 CYP19A1 ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM cytochrome P450 family 19 subfamily A member 1
TCMBANKGE000474 NCOA1 F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 nuclear receptor coactivator 1
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000784 CALM3 CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 calmodulin 3
TCMBANKGE000792 FASLG ALPS1B; APT1LG1; APTL; CD178; CD95-L; CD95L; FASL; TNFSF6; TNLG1A Fas ligand
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE000970 FASN FAS; OA-519; SDR27X1 fatty acid synthase
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001132 BAX BCL2L4 BCL2 associated X, apoptosis regulator
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001177 TP53 BCC7; BMFS5; LFS1; P53; TRP53 tumor protein p53
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1