Compound Summary

  Compound Information

TCMBANKIN036805

药名:	cantharidin
别名:	Cantharides camphor; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3a.alpha.,4.beta.,7.beta.,7a.alpha.)-; 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, 2,3-dimethyl-; EINECS 200-263-3; (1R,2S,3R,6S)-1,2-Dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride; Kantharidin [German]; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-; CAS-56-25-7; BRN 0085302; 2,3-Dimethyl-7-oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aR,4S,7R,7aS)-rel-; 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, 2,3-dimethyl-; Cantharidine; BPBio1_000738; AI3-04021; EPA Pesticide Chemical Code 013101; 2,3-Dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride; AIDS014422; HSDB 2181; CAN; CCRIS 635; 1,2-Dimethyl-3,6-epoxyperhydrophthalic anhydride; LS-1; NCGC00016247-01; NSC 61805; Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3a-alpha,4-beta,7-beta,7a-alpha); cantharidin ; BSPBio_000670; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-; WLN: T C555 A AO DVOVTJ C1 G1; exo-1,2-cis-Dimethyl-3,6-epoxyhexahydrophthalic anhydride; Hexahydro-3aalpha,7aalpha-dimethyl-4beta,7beta-epoxyisobenzofuran-1,3-dione; NCI60_005413; 5-19-05-00051 (Beilstein Handbook Reference); NCIMech_000301; AIDS-014422; 56-25-7; Cantharone; CANTHARIDIN; Kantaridin; Prestwick3_000885; Caswell No. 157; NSC61805
分子式:	C10H12O4
Smiles:	CC12C3CCC(C1(C(=O)OC2=O)C)O3
成分:	HBIN019611
OB_score:	51.234205
CAS_id:	56-25-7
SymMap_id:	SMIT04211
TCMID_id:	3094
TCMSP_id:	MOL001858
PubChem_id:	5944

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004354	Epicauta gorhami	葛上亭长			To expel stasis and break accumulation./Amenorrhea, concretion and conglomeration, accumulation-gathering, fistula.
TCMBANKHE004373	Huechys sanguinea	红娘子			To break stasis, dissipate binds, attack toxin./Scrofula, amenorrhea due to blood stasis, lumbago, infertility, lichen sore, rabid dog bite.
TCMBANKHE004746	Lytta caraganae	青娘子			To attack toxin and expel stasis./Scrofula, rabid dog bite.
TCMBANKHE006188		斑蝥			Concretion and conglomeration, intractable lichen, scrofula, wart, non-opened welling abscess and flat abscess, malign sore.
TCMBANKHE005866/YEM-264	Myrica rubra|Myrica rubra (Lour.)Sieb.et Zucc.	杨梅树皮|杨梅	杨梅	云南民族药物志：第二卷	To rectify qi and dissipate stasis, eliminate damp, relieve pain./Dysentery, knocks and falls, eye screen, toothache, burns and scalds, malign scab and lai sore.	阿昌族/傣族/德昂族/景颇族/傈僳族/水族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000018	Pancreatic Neoplasm	disease	Digestive System Diseases; Neoplasms; Endocrine System Diseases	21958460
TCMBANKDI000048	Neoplasms	group	Neoplasms	24425774
TCMBANKDI003324	Cholangiocarcinoma	disease	Neoplasms	29797403
TCMBANKDI003353	Carcinogenesis	phenotype	Pathological Conditions, Signs and Symptoms; Neoplasms	29797403
TCMBANKDI007930	Bile Duct Neoplasms	group	Digestive System Diseases; Neoplasms	29797403

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000088	PPP5C	PP5; PPP5; PPT	protein phosphatase 5 catalytic subunit
TCMBANKGE000204	CXCL8	GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8	C-X-C motif chemokine ligand 8
TCMBANKGE000338	CHUK	IKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16	component of inhibitor of nuclear factor kappa B kinase complex
TCMBANKGE000351	PTPA	PP2A; PPP2R4; PR53	protein phosphatase 2 phosphatase activator
TCMBANKGE001010	TNFRSF10A	APO2; CD261; DR4; TRAILR-1; TRAILR1	TNF receptor superfamily member 10a
TCMBANKGE001014	TNFRSF10B	CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9	TNF receptor superfamily member 10b
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8
TCMBANKGE001098	NFKBIA	EDAID2; IKBA; MAD-3; NFKBI	NFKB inhibitor alpha
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit