Compound Summary

  Compound Information

TCMBANKIN036811

药名:	brusatol
别名:	ZZZYHIMVKOHVIH-MWFXHRFLSA-N; ZINC100062210; Brusatol; ST2406734; CHEMBL450464
分子式:	C26H32O11
Smiles:	C1(=O)C([H])([H])[C@](C([H])([H])[H])([C@]2([H])[C@]3([C@]([H])([C@@](OC3([H])[H])(C(OC([H])([H])[H])=O)[C@@]([H])(O[H])[C@]2([H])O[H])[C@@]([H])(OC(=O)\C([H])=C(/C([H])([H])[H])\C([H])([H])[H])C(=O)O 4)[C@@]4([H])C5([H])[H])[C@]5([H])C(C([H])([H])[H])=C1O[H]
成分:	HBIN018930
OB_score:	45.686722
CAS_id:	14907-98-3
SymMap_id:	SMIT00277
TCMID_id:	2684
TCMSP_id:	MOL008073
PubChem_id:	137704670

---

   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003878	Folium Mahoe	十大功劳叶			Tuberculosis and hemoptysis, steaming bone tidal fever, dizziness and tinnitus, limp aching lumbus and knees, damp-heat jaundice, vaginal discharge, dysentery, wind-heat common cold, red eyes with gall, swollen welling abscess and sores.
TCMBANKHE004472		三分三			Stomachache, fracture, wind-damp pain, knocks and falls.
TCMBANKHE004138/YEM-734/XU-660	Fructus Bruceae|Brucea javanica(L.)Merr.|Brucea javanica	鸦胆子	鸦胆子	云南民族药物志：第四卷|云南省文山州富宁县	To remove toxic heat, to stop malarial attacks, to relieve dysentery, and to cauterize vegetations./Malaria, amebic dysentery, dysentery with pus and blood, tenesmus, corn and common wart.	阿昌族/傣族/德昂族/基诺族/景颇族/傈僳族/彝族/壮族

---

   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000088	Lung Neoplasms	group	Neoplasms; Respiratory Tract Diseases	21205897
TCMBANKDI003472	Endometrial Hyperplasia	disease	Female Urogenital Diseases and Pregnancy Complications	28638475
TCMBANKDI015496	Liver neoplasms	group	Digestive System Diseases; Neoplasms	31666108

---

   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000099	EIF5AL1	EIF5A; EIF5AP1; bA342M3.3; eIF-4D; eIF-5A; eIF-5A-1; eIF-5A1	eukaryotic translation initiation factor 5A like 1
TCMBANKGE000100	EIF5A	EIF-5A; EIF5A1; eIF-4D; eIF5AI	eukaryotic translation initiation factor 5A
TCMBANKGE000101	PGF	D12S1900; PGFL; PIGF; PLGF; PlGF-2; SHGC-10760	placental growth factor
TCMBANKGE000102	MAFG	hMAF	MAF bZIP transcription factor G
TCMBANKGE000103	MAFF	U-MAF; hMafF	MAF bZIP transcription factor F
TCMBANKGE000104	GSTZ1	GSTZ1-1; MAAI; MAAID; MAI	glutathione S-transferase zeta 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000223	KEAP1	INrf2; KLHL19	kelch like ECH associated protein 1
TCMBANKGE000265	SQSTM1	A170; DMRV; FTDALS3; NADGP; OSIL; PDB3; ZIP3; p60; p62; p62B	sequestosome 1
TCMBANKGE000512	BACH1	BACH-1; BTBD24	BTB domain and CNC homolog 1
TCMBANKGE000823	GABPA	E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07	GA binding protein transcription factor subunit alpha
TCMBANKGE000837	ISYNA1	INO1; INOS; IPS; IPS 1; IPS-1	inositol-3-phosphate synthase 1
TCMBANKGE001126	NFE2L2	HEBP1; IMDDHH; NRF2; Nrf-2	nuclear factor, erythroid 2 like 2