Compound Summary

  Compound Information

TCMBANKIN036812

药名:	brucine
别名:	BB_NC-0718; 399027_ALDRICH; C09084; ACon1_001990; nchembio.2007.55-comp3; 357-57-3 (FREE BASE); Brucine; InChI=1/C23H26N2O4/c1-27-16-8-14-15(9-17(16)28-2)25-20(26)10-18-21-13-7-19-23(14,22(21)25)4-5-24(19)11-12(13)3-6-29-18/h3,8-9,13,18-19,21-22H,4-7,10-11H2,1-2H; Brucina; SMR000112281; 2,3-dimethoxystrychnidin-10-one; MEGxp0_001865; 4845-99-2 (MONOSULFATE); l-Brucine; AIDS002665; AIDS-002665; MLS000515808; Brucin; UN 1570
分子式:	C23H26N2O4
Smiles:	COC1=C(C=C2C(=C1)C34CCN5C3CC6C7C4N2C(=O)CC7OCC=C6C5)OC
成分:	HBIN018923
OB_score:	7.607378
CAS_id:	357-57-3
SymMap_id:	SMIT00180
TCMID_id:	2678
TCMSP_id:	MOL003435
PubChem_id:	442021

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002292		橘红
TCMBANKHE002968	Semen Strychni Pulveratum	马钱子粉			Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores./Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores.
TCMBANKHE003490	Strychnos aculeata	刺马前子
TCMBANKHE003857	Semen Strychni	马钱子			To promote the flow of qi and blood in the collaterals, relieve pain, and promote the subsidence of swelling./Hemiplegia, numbness and paralysis, muscle weakness, impotence, hypertrophic spinitis, chronic anemia, wind-damp intractable impediment, sequel of poliomyelitis, rheumatoid arthritis, knocks and falls, swelling pain of welling abscess and flat abscess.
TCMBANKHE003858	Semen Strychni Praeparata	炙马钱子			Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores./Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores.
TCMBANKHE004431	Semen Strychni;Strychnos dolichothyrsa;Semen Cumini Cymni;Strychnos mittschelichii	马钱子			To promote the flow of qi and blood in the collaterals, relieve pain, and promote the subsidence of swelling./Hemiplegia, numbness and paralysis, muscle weakness, impotence, hypertrophic spinitis, chronic anemia, wind-damp intractable impediment, sequel of poliomyelitis, rheumatoid arthritis, knocks and falls, swelling pain of welling abscess and flat abscess.
TCMBANKHE006988	Strychnos ignatii	吕宋果			To resolve toxin, disperse swelling, kill worms, relieve pain./Stomachache, diarrhea, dysentery, malaria, worm accumulation, bleeding due to external injury, centipede bite.
TCMBANKHE004138/YEM-734/XU-660	Fructus Bruceae|Brucea javanica(L.)Merr.|Brucea javanica	鸦胆子	鸦胆子	云南民族药物志：第四卷|云南省文山州富宁县	To remove toxic heat, to stop malarial attacks, to relieve dysentery, and to cauterize vegetations./Malaria, amebic dysentery, dysentery with pus and blood, tenesmus, corn and common wart.	阿昌族/傣族/德昂族/基诺族/景颇族/傈僳族/彝族/壮族
TCMBANKHE004112/YEM-886	Fructus Rosae laevigatae|Rosa laevigata Michx.	金樱子	金樱子	云南民族药物志：第五卷	1. To control the essence; 2. To astringe the intestines and stop diarrhea; 3. To decrease urination/Emission, enuresis and frequent urination, flooding and spotting with vaginal discharge, chronic diarrhea and dysentery.	布依族/回族/苗族/水族/瑶族/彝族/藏族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI028460

Carcinoma, Ehrlich Tumor

disease

Neoplasms

23348691

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000979

KDR

CD309; FLK1; VEGFR; VEGFR2

kinase insert domain receptor