Compound Summary

  Compound Information

TCMBANKIN036825

化合物待补充

药名:	Honokiol
别名:	VZ32385; 354H746; NCGC00163567-01; HMS2051C12; 11513CCO0N; {1,1'-Biphenyl]-2,4'-diol, 3,5-di-2-propenyl-; 2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol; ZINC00001536; STK801954; AIDS002243; FVYXIJYOAGAUQK-UHFFFAOYSA-N; AC-486; SMP2_000040; 5,3′ C10630; AX8008971; NSC-293100; AS-15333; W-2613; 3',5-diallyl-2,4'-biphenyldiol; AC1Q7A9U; MLS000759481; TR-014635; 564-73-8; SR-01000758208-5; 3',5-Dipropenyl-(1,1'-biphenyl)-2,4'-diol; J10347; NC00114; SAM001246690; Bio-0326; MLS001423980; CHEBI:5759; 3'',5-diallylbiphenyl-2,4''-diol; REGID_for_CID_72303; O900; MolPort-002-507-432; SCHEMBL133034; InChI=1/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H; BC205226; AN-15767; ANW-56605; MCULE-5001549020; ACN-035410; 3,5'-Diallyl-4,2'-dihydroxybiphenyl; Honokiol, >=98% (HPLC), powder; D04DQJ; CTK5J3931; BG01559998; SR-01000758208; BRD-K98493452-001-01-6; AC1L2HTG; AB0016711; AKOS005622639; 4-allyl-2-(3-allyl-4-hydroxy-phenyl)phenol; AT-5464; 5,3''''-Diallyl-biphenyl-2,4''''-diol; RTR-014635; cid_72303; 2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol; 3',5-diallyl-[1,1'-biphenyl]-2,4'-diol; CHEMBL16901; 3',5-Diallyl-2,4'-dihydroxybiphenyl; 35354-74-6; 5,3′-Diallyl-2,4′-dihydroxybiphenyl; houpa; UNII-11513CCO0N; 3',5-di(prop-2-en-1-yl)biphenyl-2,4'-diol; CPD000387107; HY-N0003; HMS3393C12; Honokiol; Q-100425; FT-0601638; 5,3''-Diallyl-biphenyl-2,4''-diol; 3'',5-di-2-propenyl-1,1''-biphenyl-2,4''-diol; BBL027819; MFCD00016674; CCG-100864; ST24044036; AK-25837; [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propen-1-yl-; Honokiol, analytical standard; AJ-08043; BDBM50157304; 3',1'-biphenyl)-2,4'-diol; 5,3'-Diallyl-biphenyl-2,4'-diol; NSC293100; NCGC00163567-03; BG00615873; 4CN-0876; NSC 293100; H4914_SIGMA; KS-00000NQF; 3',5'-Diallyl-2,4'-biphenyldiol; SC-17371; BN0719; NCGC00163567-02; LS-174528; BB_NC-1461; s2310; 5,3'-Diallyl-2,4'-dihydroxybiphenyl; API0002927; CS-1696; I06-0428; N1672; HMS2271J07; DTXSID30188845; SMR000387107; MLS001048916; AIDS-002243; HMS3656G03; Honokiol, HO; Honokiol, European Pharmacopoeia (EP) Reference Standard; ZINC1536; Honokiol,(S); MLS006011755; [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl-; 5,3′-Diallyl-2,4′-dihydroxydiphenyl; 4-allyl-2-(3-allyl-4-hydroxyphenyl)phenol; 3',5-Diallylbiphenyl-2,4'-diol
成分:	HBIN029531
OB_score:	60.669442
CAS_id:	35354-74-6
SymMap_id:	SMIT00240
TCMID_id:	9630
TCMSP_id:	MOL005955
PubChem_id:	72303

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003858	Semen Strychni Praeparata	炙马钱子			Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores./Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores.
TCMBANKHE004771	Magnolia obovata	日本厚朴
TCMBANKHE005435	Magnolia biloba	凹叶厚朴			See Magnolia officinalis ./See Magnolia officinalis.
TCMBANKHE007292		藁本			Headache due to externally contracted wind-cold, vertex headache, pain in tooth and cheek, migraine, wind-cold-damp impediment, pain in limbs.
TCMBANKHE002734/YEM-235	Magnolia officinalis Rehd.et Wils.	厚朴子|厚朴	厚朴	云南民族药物志：第二卷		彝族
TCMBANKHE002025/YEM-235	Magnoliae Officinalis Praeparata|Magnolia officinalis Rehd.et Wils.	炙厚朴|厚朴	厚朴	云南民族药物志：第二卷	Treatment of accumulation of damp in the spleen and the stomach marked by epigastric strffiness, vomiting and diarrhea, abdominal distension and constipation due to retention of undigested food, cough and dyspnea caused by retanied damp./1. Broad-spectrum antibacterial.2. Magnocurarine, one of the active components, can relaxstriated muscles.3. Its decoction stimulates the smooth muscles of intestines and bronchii in rabbits in vitro.4. Magnocuraine may also lower blood pressure and accelerate heart rate.	彝族
TCMBANKHE005228/YEM-235	Cortex Magnoliae officilis;Magnolia officinalis|Magnolia officinalis Rehd.et Wils.	厚朴	厚朴	云南民族药物志：第二卷	To eliminate damp and relieve distension;To dry damp and disperse phlegm, precipitate qi and eliminate fullness, lower blood pressure./1. Broad-spectrum antibacterial.2. Magnocurarine, one of the active components, can relaxstriated muscles.3. Its decoction stimulates the smooth muscles of intestines and bronchii in rabbits in vitro.4. Magnocuraine may also lower blood pressure and accelerate heart rate.5.Amebic dysentery, vomiting and diarrhea, food accumulation and qi stagnation, abdominal distention and constipation, phlegm-rheum cough asthma.	彝族
TCMBANKHE007340/YEM-235	Flos Magnoliae Offcinalis|Magnolia officinalis Rehd.et Wils.	厚朴花|厚朴	厚朴	云南民族药物志：第二卷	Treatment of feeling of stuffiness and distension in the chest and epigastrium with loss of appetite./Treatment of feeling of stuffiness and distension in the chest and epigastrium with loss of appetite.	彝族
TCMBANKHE005553/YEM-839/XU-751	Fructus Anisi Stellati|Illicium verum Hook.f.|Illicium verum	八角茴香|八角	八角	云南民族药物志：第五卷|广西崇左大新县下雷镇德天瀑布	To dispel cold to regulate the flow of qi and to relieve pain./Treatment of abdominal colic, lumbago due to deficiency of the kidney, vomiting and eqigastric pain due to cold of the stomach.	阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000001	Stomach Neoplasms	group	Digestive System Diseases; Neoplasms	25619450
TCMBANKDI000007	melanoma	disease	Neoplasms	30391358
TCMBANKDI000008	Brain Neoplasms	group	Neoplasms; Nervous System Diseases	22259050
TCMBANKDI000009	Glioma	disease	Neoplasms	30587839
TCMBANKDI000048	Neoplasms	group	Neoplasms	23807168
TCMBANKDI000051	Endotoxemia	phenotype	Pathological Conditions, Signs and Symptoms; Infections	21279327
TCMBANKDI000067	Head and Neck Neoplasms	group	Neoplasms	29180609
TCMBANKDI000070	Osteosarcoma	disease	Neoplasms	29410403
TCMBANKDI000078	Skin Neoplasms	group	Neoplasms; Skin and Connective Tissue Diseases	30391358
TCMBANKDI000085	Inflammation	phenotype	Pathological Conditions, Signs and Symptoms	22429472
TCMBANKDI000093	Sepsis	disease	Pathological Conditions, Signs and Symptoms; Infections	21279327
TCMBANKDI002310	Kidney Neoplasm	disease	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases	23752066
TCMBANKDI003011	Staphylococcal Infections	group	Infections	31119985
TCMBANKDI010465	Sleep Initiation and Maintenance Disorders	disease	Nervous System Diseases; Mental Disorders	22537192
TCMBANKDI012424	Neoplasm Invasiveness	phenotype	Pathological Conditions, Signs and Symptoms; Neoplasms	25619450
TCMBANKDI013888	Fibrosis	phenotype	Pathological Conditions, Signs and Symptoms	21265825
TCMBANKDI014031	Peritoneal Neoplasms	group	Digestive System Diseases; Neoplasms	30391358
TCMBANKDI015452	Thyroid Neoplasm	disease	Neoplasms; Endocrine System Diseases	27940017
TCMBANKDI017642	Squamous cell carcinoma	disease	Neoplasms	29180609
TCMBANKDI018012	Ureteral obstruction	phenotype	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases	21265825
TCMBANKDI018458	Intervertebral Disc Degeneration	disease	Musculoskeletal Diseases	29649568
TCMBANKDI020247	Cardiomegaly	phenotype	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases	25871545
TCMBANKDI024649	Neuroblastoma	disease	Neoplasms	26454217
TCMBANKDI026275	Glioblastoma	disease	Neoplasms	30587839
TCMBANKDI026766	Vitiligo	disease	Skin and Connective Tissue Diseases	31037127
TCMBANKDI029884	Acute Lung Injury	disease	Respiratory Tract Diseases	21279327

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000118	CAPN2	CANP2; CANPL2; CANPml; mCANP	calpain 2
TCMBANKGE000139	POR	CPR; CYPOR; P450R	cytochrome p450 oxidoreductase
TCMBANKGE000146	CAPN10	CANP10; NIDDM1	calpain 10
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000241	CASP8	ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5	caspase 8
TCMBANKGE000276	NOS1	IHPS1; N-NOS; NC-NOS; NOS; bNOS; nNOS	nitric oxide synthase 1
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000315	IL4	BCGF-1; BCGF1; BSF-1; BSF1; IL-4	interleukin 4
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000458	CYP2B6	CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450	cytochrome P450 family 2 subfamily B member 6
TCMBANKGE000474	NCOA1	F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74	nuclear receptor coactivator 1
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000654	CAPN1	CANP; CANP1; CANPL1; SPG76; muCANP; muCL	calpain 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000820	CFLAR	CASH; CASP8AP1; CLARP; Casper; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; cFLIP	CASP8 and FADD like apoptosis regulator
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001001	SNCA	NACP; PARK1; PARK4; PD1	synuclein alpha
TCMBANKGE001041	ALOX15	12-LOX; 15-LOX; 15-LOX-1; LOG15	arachidonate 15-lipoxygenase
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001054	ABCA1	ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD	ATP binding cassette subfamily A member 1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001107	NOS3	ECNOS; eNOS	nitric oxide synthase 3
TCMBANKGE001131	CASP9	APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56	caspase 9
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001173	MCL1	BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT	MCL1 apoptosis regulator, BCL2 family member
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001467	LTA4H	-	leukotriene A4 hydrolase
TCMBANKGE001755	MAOB	-	monoamine oxidase B
TCMBANKGE001943	ADRA1D	ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2	adrenoceptor alpha 1D
TCMBANKGE001966	RASGRF2	GRF2; RAS-GRF2	Ras protein specific guanine nucleotide releasing factor 2
TCMBANKGE002094	CAPN3	CANP3; CANPL3; LGMD2; LGMD2A; LGMDD4; LGMDR1; nCL-1; p94	calpain 3
TCMBANKGE003010	CAPN9	GC36; nCL-4	calpain 9
TCMBANKGE003183	CAPN11	calpain11	calpain 11
TCMBANKGE003625	SLC6A4	5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT	solute carrier family 6 member 4
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006282	CAPN8	nCL-2	calpain 8
TCMBANKGE006373	TYW1	RSAFD1; TYW1A; YPL207W	tRNA-yW synthesizing protein 1 homolog
TCMBANKGE006943	CHRM3	EGBRS; HM3; PBS	cholinergic receptor muscarinic 3
TCMBANKGE007670	CAPN12	-	calpain 12
TCMBANKGE007737	CAPN13	-	calpain 13
TCMBANKGE007924	PKIA	PRKACN1	cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE008423	CAPN15	SOLH	calpain 15
TCMBANKGE008750	CAPN7	CALPAIN7; PALBH	calpain 7
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE008975	CAPN14	-	calpain 14
TCMBANKGE009256	SLC6A2	NAT1; NET; NET1; SLC6A5	solute carrier family 6 member 2
TCMBANKGE009776	CAPN6	CANPX; CAPNX; CalpM; DJ914P14.1	calpain 6
TCMBANKGE009863	MTRR	MSR; cblE	5-methyltetrahydrofolate-homocysteine methyltransferase reductase
TCMBANKGE010043	PPIF	CYP3; CyP-M; Cyp-D; CypD	peptidylprolyl isomerase F
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE011356	NDOR1	CIAE1; NR1; bA350O14.9	NADPH dependent diflavin oxidoreductase 1
TCMBANKGE011544	IGHG1	-	immunoglobulin heavy constant gamma 1 (G1m marker)
TCMBANKGE011625	ADGB	C6orf103; CAPN16	androglobin
TCMBANKGE011923	CHRM4	HM4; M4R	cholinergic receptor muscarinic 4
TCMBANKGE012155	SLC6A3	DAT; DAT1; PKDYS; PKDYS1	solute carrier family 6 member 3
TCMBANKGE014062	CAPN5	ADNIV; HTRA3; VRNI; nCL-3	calpain 5
TCMBANKGE014423	ADRA1A	ADRA1C; ADRA1L1; ALPHA1AAR	adrenoceptor alpha 1A