Compound Summary


  Compound Information

药名:

hesperetin

别名:

BSPBio_000168; KBio1_001039; BCBcMAP01_000087; CAS-520-33-2; C01709; KBio2_005797; (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one; Spectrum3_001104; KBioGR_002311; IDI1_001039; 520-33-2; Prestwick0_000124; CHEBI:61249; EINECS 208-290-2; SPBio_001745; KBio2_003229; KBio2_000661; NSC 57654; NCGC00016482-02; Spectrum2_001793; hesperetin(1-); 3',5,7-Trihydroxy-4'-methoxyflavanone; (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)chroman-4-one; Prestwick1_000124; ZINC00039092; AIDS-001413; (-)-hesperetin; Prestwick_908; BPBio1_000186; (S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone; Spectrum5_000683; NCGC00142415-02; NINDS_001039; (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxochroman-7-olate; Spectrum4_001935; Oprea1_828704; TNP00238; Prestwick3_000124; H4125_SIGMA; CHEBI:28230; SDCCGMLS-0066605.P001; KBio3_002028; SMP1_000148; SPBio_002107; DivK1c_001039; Flavanone, 3',5,7-trihydroxy-4'-methoxy- (VAN) (8CI); hesperetin; Prestwick2_000124; 3′,5,7-Trihydroxy-4-methoxyflavanone; Spectrum_000181; NCGC00016482-01; SPECTRUM310012; KBioSS_000661; AIDS001413; NCGC00142415-01; hesperetin anion; (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone; YSO2; (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one; SBB005936; 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)- (9CI); BSPBio_002808; (2S)-hesperetin; (S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

分子式:

C16H14O6

Smiles:

c1(O[H])c([H])c(O[C@@]([H])(c2c([H])c([H])c(OC([H])([H])[H])c(O[H])c2[H])C([H])([H])C3=O)c3c(O[H])c1[H]

成分:

HBIN029190

OB_score:

70.312089

CAS_id:

520-33-2

SymMap_id:

SMIT04602;SMIT15739

TCMID_id:

9455

TCMSP_id:

MOL002341

PubChem_id:

72281


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000848 Radix Echinopsis 禹州漏芦 To remove heat and counteract toxicity, drainage of pus, stanch bleeding, to cure sores and carbuncles, increase the secretion of milk./Treatment of sores, carbuncles, swelling and pain due to mastitis, galactostasis, tuberculosis of lypmhaden, pyogenic infection. It can be used as antheimintic.
TCMBANKHE004523 Flos Gossampini 木棉花 Diarrhea, dysentery, hemoptysis, blood ejection, flooding, incised wound and bleeding, sore toxin, eczema.
TCMBANKHE003463 荆芥穗
TCMBANKHE005462 Bulbus Allii Macrostemi 薤白 To remove the retained phlegm from the chest, promote the flow of qi and relieve its stagnation./Chest impediment, phlegm-rheum cough asthma, diarrhea and tenesmus.
TCMBANKHE003843 Citrus limon 柠檬 To engender liquid and allay thirst, dispel summerheat, quiet fetus./Stomach heat fluid damage, summerheat stroke with vexation and thirst, inappetence, glomus distention in stomach duct and abdomen, lung heat dry cough, vomiting in pregnancy.
TCMBANKHE007122 Fructus Aurantii Immaturus 枳实 To eliminate stagnation of qi, resolve phlegm and relieve stuffiness sensation in the chest and abdomen./Shock, indigestion, ptosis of anus or uterus, cardiac failure, distention fullness in chest and abdomen, phlegm aggregation.
TCMBANKHE005239 Fructus Aurantii 枳壳 To regulate the flow of qi, remove its stagnation, and alleviate distension;Treatment of distension and pain in the chest and hypochondriac regions due to stagnation of qi, indigestion with retention of phlegm and fluid, gastroptosis, prolapse of the rectum, prolapse of the uterus./Phlegm stagnation in chest and diaphragm, glomus in chest, distention in rib-side, food accumulation, retching counterflow.
TCMBANKHE007669 香橼 See Citrus medica .
TCMBANKHE006403 Herba Schizonepetae 荆芥 To induce diaphoresis, to dispel wind, and to promote eruptions./Common cold with fever, headache, itchy eye, cough, swelling pain in throat, measles papules, wind papules, swollen welling abscess, sore and scab, throat pain, conjunctivitis, child measles, spontaneous external bleeding, blood ejection, hematochezia, flooding and spotting, postpartum blood dizziness.
TCMBANKHE007238 Radix Stephaniae Tetrandrae 防己 To cause diuresis and to relieve rheumatic conditions./Beriberi with edema, inhibited urination, eczema, sore toxin, wind-damp impediment pain, hypertension, adjuvant in anesthesia.
TCMBANKHE007604 Herba Glechomae Longitubae 金钱草 To remove damp-heat, relieve dysuria, and to promote subsidence of swelling./Increasing biliary secretion.
TCMBANKHE006991 胡黄连 Steaming bone tidal fever due to yin vacuity, night sweating, child gan accumulation, indigestion, abdominal distention and emaciation, dysentery, fever, gastrointestinal damp-heat diarrhea, hemorrhoids.
TCMBANKHE008943 Citrus unshiu 无核蜜桔 See Citrus chachiensis./See Citrus chachiensis .
TCMBANKHE004408/XU-275/XU-602 Artemisia lactiflora 鸭脚艾|白苞蒿 云南省昭通市盐津县 To quicken blood and dissipate stasis, rectify qi and transform damp./Dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, chronic hepatitis, liver spleen enlargement, food accumulation abdominal distention, cold-damp diarrhea, mounting qi , beriberi, knocks and falls, burns and scalds.
TCMBANKHE007941/YEM-822 Herba Schizonepetae|Schizonepeta tenuifolia(Benth.)Briq. 荆芥|裂叶荆芥 裂叶荆芥 云南民族药物志:第四卷 To induce diaphoresis, to dispel wind, and to promote eruptions./Common cold with fever, headache, itchy eye, cough, swelling pain in throat, measles papules, wind papules, swollen welling abscess, sore and scab, throat pain, conjunctivitis, child measles, spontaneous external bleeding, blood ejection, hematochezia, flooding and spotting, postpartum blood dizziness. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE007056/YEM-9 Herba Lobeliae Chinensis|Lobelia chinensis Lour. 半边莲 半边莲 云南民族药物志:第一卷 To cause diuresis, and to remove toxic heat./Edema, edema and enlarged abdomen, edema in face and foot, swollen welling abscess and clove sores, snake or insect bites. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE004276/YEM-974 Citrus sinensis|Citrus sinensis(L.)Osbeck 甜橙 黄果树 云南民族药物志:第五卷 To move qi, precipitate qi, relieve pain, disperse distention, free milk./Galactostasis. 布依族/水族/佤族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000026 Obesity disease Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 29160087
TCMBANKDI018635 Liver Failure, Acute disease Digestive System Diseases 27714757

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000474 NCOA1 F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 nuclear receptor coactivator 1
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1