Compound Summary
Compound Information
化合物待补充
药名: | Bicuculline |
别名: | Prestwick3_000589; IDI1_000609; Biomol-NT_000252; C09364; Bicuculline (+); BPBio1_000482; 4-27-00-06900 (Beilstein Handbook Reference); KBio2_005897; SPBio_002657; Bicculine; SPBio_000933; AC1Q6H29; 485-49-4; Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))-; KBio2_000761; BRD-A09495397-001-01-9; 14340_FLUKA; BPBio1_000794; NSC32192; (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[4,3-g][1,3]benzodioxol-8-one; KBio2_003329; d-Bicuculline; 10-[(5S)-6-METHYL-2H,5H,7H,8H-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5-YL]-3,5,11-TRIOXATRICYCLO[7.3.0.0(2),?]DODECA-1,6,8-TRIEN-12-ONE; DivK1c_000609; CCG-40040; ()-Bicuculline; Lopac0_000234; WLN: T C566 DO FO KN EH&&TJ K1 J- ET B565 CVO JO LO EH KHJ; Bicuculline; Prestwick2_000589; Spectrum2_000717; Bicucullin; 6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one; AC1O8JS3; EINECS 207-619-7; ST057559; KBioGR_001740; NINDS_000609; BRN 0098786; BSPBio_000438; Furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [R-(R*,S*)]-; Spectrum4_001240; KBioSS_000761; CHEBI:93802; Prestwick_96; KBio1_000609; Spectrum_000281; (+)-Bicuculline; PDSP2_000138; NSC 32192; Prestwick0_000589; Prestwick1_000589 |
成分: | HBIN018403 |
OB_score: | 69.667464 |
CAS_id: | 485-49-4 |
SymMap_id: | SMIT00424 |
TCMID_id: | 2350 |
TCMSP_id: | MOL000791 |
PubChem_id: | 10237 |
DrugBank_id: | DB11562 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE006167 | Herba Corydalis bungeae | 苦地丁 | Influenza, infection of upper respiratory tract, tonsillitis, infective hepatitis, enteritis, dysentery, nephritis, parotitis, conjunctivitis, acute appendicitis, clove sore and swollen welling abscess, scrofula. | |||
| TCMBANKHE002048 | Corydalis gigantea | 巨紫荆 | To settle pain and calm./Various pains. | |||
| TCMBANKHE003799 | Fructus Forsythiae | 连翘 | To remove toxic heat, to cause subsidence of sweeling,and to eliminate modulation./Influenza in early stage, common cold in early stage, wind-heat common cold, encephalitis, hepatitis, tuberculosis, warm disease, heat strangury with inhibited pain, welling abscess, welling abscess and flat abscess, toxin swelling, scrofula, goiter and tuberculosis, throat impediment. | |||
| TCMBANKHE003826 | Rhizoma Cimicifugae | 升麻 | To induce perspiration and promote eruption, to remove toxic heat, and to cure drooping and ptosis./Prevention of ptosis, women’s hormone dysfunction diseases, seasonal epidemic fire toxin, mouth sore, sore pharynx, macula, cold-heat headache, swelling toxin of welling abscess and sore, center qi fall, spleen vacuity diarrhea, chronic dysentery, vaginal discharge, flooding. | |||
| TCMBANKHE004088 | Rhizoma Corydalis Decumbentis | 夏天无 | To promote the flow of qi and blood, to remove obstruction from the collaterals and to relieve pain./Pain in deep tissues, neuralgia, swelling pain from fracture, hypertension, hemiplegia, sequel of poliomyelitis, sciatica, rheumatic arthritis, knocks and falls. | |||
| TCMBANKHE004376 | Pericarpium Grati | 石榴皮 | To check diarrhea, arrest bleeding and repel worms./Chronic diarrhea, chronic dysentery, hematochezia, prolapse of rectum, flooding and spotting, leukorrhea, abdominal pain due to worm accumulation. | |||
| TCMBANKHE004485 | Radix Oryzae Glutinosae | 糯稻根 | To stop cold sweat and lower asthenic fever. | |||
| TCMBANKHE006212 | Semen Astragali Complanati;Semen Astragali Complati | 潼蒺藜;沙苑子 | Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision,to benefit the liver./Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision. | |||
| TCMBANKHE004522 | Rhizoma Corydalis | 延胡索 | 1. To invigorate blood and promote qi circulation; 2. To stop pain/Chest and rib-side pain, pain in stomach duct and abdomen, neuralgia, gastrointestinal spasm, amenorrhea and dysmenorrhea, postpartum stasis stagnation abdominal pain, painful swelling from knocks and falls. | |||
| TCMBANKHE008498 | fructus Sophorae | 槐角 | For cooling blood and stopping bleeding | |||
| TCMBANKHE009011 | Corydalis mucronifera | 扁柄黄堇 | To clear heat and resolve toxin, relieve pain./Influenza, warm disease fever, gastritis, ulcer, dysentery, sciatica, swelling pain of sore and boil. | |||
| TCMBANKHE008004 | Corydalis ambigua var. amurensis [Syn. Corydalis ambigua] | 东北延胡索 | To quicken blood and dissipate stasis, rectify qi and relieve pain./Pain in lumbus and knees, pain in heart and abdomen, dysmenorrhea, menstrual disorder, postpartum stasis stagnation abdominal pain, flooding and spotting, concretion and conglomeration, knocks and falls. | |||
| TCMBANKHE007869/YEM-680 | Corydalis taliensis|Corydalis taliensis Franch. | 五味草|金钩如意草 | 金钩如意草 | 云南民族药物志：第四卷 | To dispel wind, clear heat, relieve pain, clear liver and brighten eyes./Wind-heat common cold, lung heat cough, tuberculosis and coughing of blood, hepatitis, wind-damp pain in sinews and bones, toothache, red eyes, eye screen. | 傈僳族/彝族/藏族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000221 | GRIA2 | GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B | glutamate ionotropic receptor AMPA type subunit 2 |
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