Compound Summary


  Compound Information

药名:

wogonoside

别名:

wogoninoglucuronide; N2501; wogonoside ; (2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-5-(5-hydroxy-8-methoxy-4-oxo-2-phenylchromen-7-yl)-6-oxohexanoic acid; AC-20339; ZINC21992923; Y0212; BG01748878; AKOS015965557

分子式:

C22H20O12

Smiles:

[C@]1([H])(O[H])[C@@]([H])(C(=O)O[H])O[C@@]([H])(Oc2c(OC([H])([H])[H])c(OC(c3c([H])c([H])c([H])c([H])c3[H])=C([H])C4=O)c4c(O[H])c2O[H])[C@]([H])(O[H])[C@@]1([H])O[H]

成分:

HBIN048376

SymMap_id:

SMIT18228

TCMID_id:

22704

PubChem_id:

12004622


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000757 Radix Adenophorae 南沙参 To nourish yin and remove heat from the lung, to relieve phlegm, and to reinforce qi./Treament of heat in the lung with dry cough, cough with scanty sticky sputum in phthisis with deficiency of yin , deficiency of both qi and yin with feverishness and thirst.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003799 Fructus Forsythiae 连翘 To remove toxic heat, to cause subsidence of sweeling,and to eliminate modulation./Influenza in early stage, common cold in early stage, wind-heat common cold, encephalitis, hepatitis, tuberculosis, warm disease, heat strangury with inhibited pain, welling abscess, welling abscess and flat abscess, toxin swelling, scrofula, goiter and tuberculosis, throat impediment.
TCMBANKHE005914 Scutellaria likiangensis 丽江黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE005975 Scutellaria hypericifolia 川黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE005123 Scutellaria viscidula 粘毛黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE005273 Anodendron affine 山藤;鳝藤
TCMBANKHE008381 Scutellaria rehderiana 甘肃黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE007163 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE008975 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE006914 Ramulus Euonymi 鬼箭羽 For activating blood and modulating period/Concretion and conglomeration, pain in heart and abdomen, amenorrhea, dysmenorrhea, postpartum stasis stagnation abdominal pain, retention of lochia, mounting qi , joint running impediment pain, swelling of sores, painful wound from knocks and falls, burns and scalds, poisonous snake bite.
TCMBANKHE007847 Caulis Millettiae; Caulis spatholobi 鸡血藤 To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE007803 Herba Scutellariae barbatae 半枝莲 To remove toxic heat, and to cause diuresis./Heat toxin swollen welling abscess, throat pain, pulmonary welling abscess, intestinal welling abscess, scrofula, poisonous snake bite, knocks and falls, blood ejection, spontaneous external bleeding, blood strangury, edema, ascites, carcinoma.
TCMBANKHE003759/YNS-62/YEM-852/XU-165 Scutellaria amoena|Scutellaria amoena C. H. Wright|Scutellaria amoena C.H.Wright 滇黄芩 滇黄芩 云南药材标准:第七册|云南民族药物志:第五卷|云南省昆明市盘龙区茨坝长虫山 清热燥湿,泻火解毒,止血,安胎。用于湿温、暑湿,胸闷呕恶,湿热痞满,泻痢,黄疸,肺热咳嗽,高热烦渴,血热吐衄,痈肿疮毒,胎动不安。|See Scutellaria baicalensis./See Scutellaria baicalensis. 布依族/德昂族/傈僳族/苗族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000053 leukemia disease Neoplasms 28492556
TCMBANKDI012424 Neoplasm Invasiveness phenotype Pathological Conditions, Signs and Symptoms; Neoplasms 28774312

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000053 NFKB1 CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB nuclear factor kappa B subunit 1
TCMBANKGE000280 VIM - vimentin
TCMBANKGE000294 CDKN1A CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 cyclin dependent kinase inhibitor 1A
TCMBANKGE000334 GATA1 ERYF1; GATA-1; GF-1; GF1; NF-E1; NFE1; XLANP; XLTDA; XLTT GATA binding protein 1
TCMBANKGE000335 ITPR1 ACV; CLA4; INSP3R1; IP3R; IP3R1; PPP1R94; SCA15; SCA16; SCA29 inositol 1,4,5-trisphosphate receptor type 1
TCMBANKGE000336 PLSCR1 MMTRA1B phospholipid scramblase 1
TCMBANKGE000337 TRAF4 CART1; MLN62; RNF83 TNF receptor associated factor 4
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000751 TRAF2 MGC:45012; RNF117; TRAP; TRAP3 TNF receptor associated factor 2
TCMBANKGE000771 TWIST1 ACS3; BPES2; BPES3; CRS; CRS1; CSO; SCS; SWCOS; TWIST; bHLHa38 twist family bHLH transcription factor 1
TCMBANKGE000898 MYC MRTL; MYCC; bHLHe39; c-Myc MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000909 GLI1 GLI; PAPA8; PPD1 GLI family zinc finger 1
TCMBANKGE000916 SMO CRJS; FZD11; Gx; SMOH smoothened, frizzled class receptor
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE001045 CCND1 BCL1; D11S287E; PRAD1; U21B31 cyclin D1
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001148 VEGFA MVCD1; VEGF; VPF vascular endothelial growth factor A
TCMBANKGE001170 CDK4 CMM3; PSK-J3 cyclin dependent kinase 4