Compound Summary


  Compound Information

药名:

wogonin

别名:

CTK5B8471; AIDS-001403; CCG-208499; ZB015158; 5,7-dihydroxy-8-methoxyflavone; ZINC899093; 5,7-dihydroxy-8-methoxy-2-phenyl-chromone; BG01576594; AN-46964; 632-85-9; V1530; MCULE-9854289767; 5,7-dihydroxy-8-methoxy-2-phenyl-4-chromenone; Vogonin; AIDS001403; NSC717845; SC-25044; 10-29-7; AC1NQYXJ; 5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one(Wogonin); NCGC00247464-01; IN1943; ZINC111327191; BN0711; 4H-1-Benzopyran-4-one,5,7-dihydroxy-8-methoxy-2-phenyl-; s4743; SR-05000002216-2; Norwogonin 8-methyl ether; 5,7-dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one; 5,7-dihydroxy-8-methoxy-2-phenylchromen-4-one; HY-N0400; BDBM50140257; MFCD12828871; ST077088; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-methoxy-2-phenyl-; DTXSID70212557; 5,7-dihydroxy-8-methoxy-2-phenyl-chromen-4-one; 632W859; MFCD00017736; CHEBI:10043; 5,7-dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one; BRN 0287152; Wogonin; N1283; SCHEMBL139083; LMPK12111330; I14-8669; NCI60_040649; HMS2270G08; FT-0603499; wagonin; 5-18-04-00571 (Beilstein Handbook Reference); Q-100730; MolPort-001-742-489; SMR001397111; POK93PO28W; AC-20338; MLS002473006; SR-05000002216; CS-3959; CHEMBL16171; D00MXS; 4CN-1056; wogonin ; AKOS015917860; UNII-POK93PO28W; TR-021802; NSC-717845; C-17890; LS-68974; 5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one; FLAVONE, 5,7-DIHYDROXY-8-METHOXY-; XLTFNNCXVBYBSX-UHFFFAOYSA-N; C10197; GP7400; 5,7-Dihydroxy-8-methoxyflavone

分子式:

C16H12O5

Smiles:

COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)O

成分:

HBIN048372

OB_score:

30.684567

CAS_id:

632-85-9

SymMap_id:

SMIT00392

TCMID_id:

22702

TCMSP_id:

MOL000173

PubChem_id:

5281703


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003021 关黄柏
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003799 Fructus Forsythiae 连翘 To remove toxic heat, to cause subsidence of sweeling,and to eliminate modulation./Influenza in early stage, common cold in early stage, wind-heat common cold, encephalitis, hepatitis, tuberculosis, warm disease, heat strangury with inhibited pain, welling abscess, welling abscess and flat abscess, toxin swelling, scrofula, goiter and tuberculosis, throat impediment.
TCMBANKHE005444 白鲜皮 To clear heat and dry damp, dispel wind and relieve itch, resolve toxin./1. Inhibiting the growth of pathogenic fungi. 2. Its infusion lowers vaccine-induced fever in rabbits. 3. Dictamnine, one of its active components, increase the myocardial tone of frogs. Dermatitis, psoriasis, icterohepatitis, damp-heat sore and papules, profuse pus, yellow-water sore, damp ulceration on skin, itchy skin, damp-heat jaundice, damp-heat impediment.
TCMBANKHE005914 Scutellaria likiangensis 丽江黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE004192 黄芩
TCMBANKHE005975 Scutellaria hypericifolia 川黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE004287 Radix Achyranthis bidentatae 牛膝 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat.
TCMBANKHE004404 Lignum Aquilariae Resitum 沉香 To promote the flow of qi and relieve pain, to arrest vomiting by warming the stomach, and to relieve asthma./Cold pain in stomach duct and abdomen, qi counterflow with asthma, stomach cold with retching counterflow, vacuity cold in lumbus and knees, vacuity constipation, qi strangury.
TCMBANKHE004980 Bupleurum scorzonerifolium 红柴胡 See Bupleurum chinense./See Bupleurum chinense.
TCMBANKHE005123 Scutellaria viscidula 粘毛黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE005273 Anodendron affine 山藤;鳝藤
TCMBANKHE005328 Radix Stellariae 银柴胡 1. To reduce heat caused by deficient yin; 2. To clear heat in infants caused by malnutrition/Yin vacuity fever, steaming bone taxation fever, child gan fever.
TCMBANKHE005421 Physalis minima 天泡子 To percolate damp and kill worms./Jaundice, inhibited urination, chronic cough and asthma, gan disease, scrofula, heaven-borne sore, damp sore.
TCMBANKHE007803 Herba Scutellariae barbatae 半枝莲 To remove toxic heat, and to cause diuresis./Heat toxin swollen welling abscess, throat pain, pulmonary welling abscess, intestinal welling abscess, scrofula, poisonous snake bite, knocks and falls, blood ejection, spontaneous external bleeding, blood strangury, edema, ascites, carcinoma.
TCMBANKHE006209 Rhizoma Atractylodis 苍术 To remove damp and invigorate the function of the spleen, to disple wind-cold, and to improve eyesight./Spleen-stomach damp turbidity, fatigue hypodynamia, glomus in chest, abdominal distention, inappetence, vomiting and diarrhea, phlegm-rheum, damp edema, exterior damp, heavy head and generalized pain, damp impediment, aching pain in limbs, crippling wilt, night blindness.
TCMBANKHE006914 Ramulus Euonymi 鬼箭羽 For activating blood and modulating period/Concretion and conglomeration, pain in heart and abdomen, amenorrhea, dysmenorrhea, postpartum stasis stagnation abdominal pain, retention of lochia, mounting qi , joint running impediment pain, swelling of sores, painful wound from knocks and falls, burns and scalds, poisonous snake bite.
TCMBANKHE008381 Scutellaria rehderiana 甘肃黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE006357 水飞蓟 Acute hepatitis, chronic hepatitis, cirrhosis, fatty liver, gallstones, cholangitis.
TCMBANKHE007163 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE008975 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE008210 Scutellaria epilobifolia 柳叶菜黄芩
TCMBANKHE008359 Semen Oroxyli 木蝴蝶 To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE008911/YEM-126 Radix Achyranthis bidentatae|Achyranthes bidentata Blume 牛膝;怀牛膝|牛膝 牛膝 云南民族药物志:第一卷 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward.Treament of soreness of the lumbar and knee joints with weakness inthe legs, amenorrhea with mass formation in the abdomen, dizziness due to hyperactivity of the liver./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE007748/YEM-22/XU-390 Herba andrographitis|Andrographis paniculata (Burm. f,)Nees|Andrographis paniculata 穿心莲 穿心莲 云南民族药物志:第一卷|云南省普洱市镇沅县 1. To clear heat and release toxins; 2. To dry dampness/Infection of upper respiratory tract, fever, wind-heat common cold, bacillary dysentery, diarrhea, tonsillitis, pneumonia, tuberculosis, lung heat cough, pulmonary welling abscess, postlithotripsy urinary tract infection, warm disease fever, pertussis, swelling pain in throat, damp-heat jaundice, strangury syndrome, erysipelas, sore and welling abscess, eczema, poisonous snake bite. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE008622/YNS-103/YEM-312/XU-348 Arachis hypogaea|Arachis hypogaea Linn.|Arachis hypogaea L. 落花生 花生壳|落花生 云南药材标准:第七册|云南民族药物志:第二卷|云南省文山州广南县 健脾化痰、敛肺止咳。用于痰浊咳嗽。|To fortify spleen and nourish stomach, moisten lung and transform phlegm./Stomach reflux, scant breast milk, beriberi, lung heat dry cough, dry stool. 傣族/哈尼族/佤族
TCMBANKHE006781/YEM-333 Radix Saposhnikoviae divaricatae|Saposhnikovia divaricata (Turcz.)Schischk. 防风 防风 云南民族药物志:第二卷 To induce diaphoresis, to dispel wind, to alleviate rheumatic conditions, and to relieve spasm./Migraine, headache and generalized pain, common cold, rheumatoid arthritis, externally contracted wind-cold, wind-damp impediment pain, aching pain in joints, abdominal pain and diarrhea, intestinal wind bleeding, tetanus, wind papule itching, sores. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE003759/YNS-62/YEM-852/XU-165 Scutellaria amoena|Scutellaria amoena C. H. Wright|Scutellaria amoena C.H.Wright 滇黄芩 滇黄芩 云南药材标准:第七册|云南民族药物志:第五卷|云南省昆明市盘龙区茨坝长虫山 清热燥湿,泻火解毒,止血,安胎。用于湿温、暑湿,胸闷呕恶,湿热痞满,泻痢,黄疸,肺热咳嗽,高热烦渴,血热吐衄,痈肿疮毒,胎动不安。|See Scutellaria baicalensis./See Scutellaria baicalensis. 布依族/德昂族/傈僳族/苗族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000029 Body Weight phenotype Pathological Conditions, Signs and Symptoms 23623334
TCMBANKDI000048 Neoplasms group Neoplasms 30031170
TCMBANKDI000053 leukemia disease Neoplasms 29326123
TCMBANKDI000085 Inflammation phenotype Pathological Conditions, Signs and Symptoms 28237856
TCMBANKDI000096 Hyperglycemia disease Nutritional and Metabolic Diseases 23623334
TCMBANKDI000160 Hypersensitivity group Immune System Diseases 25629436
TCMBANKDI002740 Uterine Cervical Neoplasm disease Neoplasms; Female Urogenital Diseases and Pregnancy Complications 23955116
TCMBANKDI015740 Colorectal Neoplasms group Digestive System Diseases; Neoplasms 24901054
TCMBANKDI019619 Dyslipidemias group Nutritional and Metabolic Diseases 23623334

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000051 IL1B IL-1; IL1-BETA; IL1F2; IL1beta interleukin 1 beta
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000053 NFKB1 CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB nuclear factor kappa B subunit 1
TCMBANKGE000160 COL2A1 ANFH; AOM; COL11A3; SEDC; STL1 collagen type II alpha 1 chain
TCMBANKGE000161 ADAMTS4 ADAMTS-2; ADAMTS-4; ADMP-1 ADAM metallopeptidase with thrombospondin type 1 motif 4
TCMBANKGE000162 MMP13 CLG3; MANDP1; MDST; MMP-13 matrix metallopeptidase 13
TCMBANKGE000163 TNFRSF1B CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR TNF receptor superfamily member 1B
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000223 KEAP1 INrf2; KLHL19 kelch like ECH associated protein 1
TCMBANKGE000230 ADIPOQ ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 adiponectin, C1Q and collagen domain containing
TCMBANKGE000301 SLC2A1 CSE; DYT17; DYT18; DYT9; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN solute carrier family 2 member 1
TCMBANKGE000338 CHUK IKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16 component of inhibitor of nuclear factor kappa B kinase complex
TCMBANKGE000389 MMP3 CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 matrix metallopeptidase 3
TCMBANKGE000698 TIGAR C12orf5; FR2BP TP53 induced glycolysis regulatory phosphatase
TCMBANKGE000824 RB1 OSRC; PPP1R130; RB; p105-Rb; p110-RB1; pRb; pp110 RB transcriptional corepressor 1
TCMBANKGE000933 IKBKB IKK-beta; IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB inhibitor of nuclear factor kappa B kinase subunit beta
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001089 PARP1 ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 poly(ADP-ribose) polymerase 1
TCMBANKGE001103 MDM2 ACTFS; HDMX; LSKB; hdm2 MDM2 proto-oncogene
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001126 NFE2L2 HEBP1; IMDDHH; NRF2; Nrf-2 nuclear factor, erythroid 2 like 2
TCMBANKGE001131 CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 caspase 9
TCMBANKGE001132 BAX BCL2L4 BCL2 associated X, apoptosis regulator
TCMBANKGE001141 PPARA NR1C1; PPAR; PPARalpha; hPPAR peroxisome proliferator activated receptor alpha
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001173 MCL1 BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT MCL1 apoptosis regulator, BCL2 family member
TCMBANKGE001177 TP53 BCC7; BMFS5; LFS1; P53; TRP53 tumor protein p53