Compound Summary


  Compound Information
化合物待补充

药名:

Sophoridine

别名:

.alpha.-Matrine; FT-0696735; MLS000029265; FT-0603438; HMS2269A14; NSC-143088; SR-01000601144-3; HMS1611N16; NSC-318810; Sophoridin; SMR000011610; FT-0628171; (5-beta)-Matridin-15-one; Oprea1_860679; Oprea1_680866; Matridin-15-one, (5-beta)- (9CI); BAS 02913238; Matrene, (+)-; NEW BASE STRUCTURE; MolPort-001-985-870; 6.beta.,7.beta.-Matrine; 2,3,5,6,6a,10,11,11a,11b,11c-Decahydro-4H,7H-3a,7a-diaza-1H-benzo[de]anthracene-8(9H)-one; Matridin-15-one; Dihydro-5-episophocarpine; SR-01000601144; SCHEMBL8260145; NSC318810; dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one; W-3063; CHEMBL1733145; regid845916; ZX-AN036540; 83148-91-8; MFCD02735434; AC1L63MI; AB00397099-11; 1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-; AKOS017259293; ALBB-020900; AKOS000591194; NSC143088; MCULE-1489142812; Q-100583; BB_NC-1021; 5-Epidihydrosophocarpine; ZSBXGIUJOOQZMP-UHFFFAOYSA-N; 6882-68-4; (+)-Matrine; Sophoridine; SC-25809; l-Sophoridine; Dodecahydro-3a,7a-diaza-benzo[de]anthracen-8-one; 4CN-1610

成分:

HBIN044394

OB_score:

60.070328

CAS_id:

6882-68-4

SymMap_id:

SMIT00187

TCMID_id:

20084

TCMSP_id:

MOL003680

PubChem_id:

165549


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000960 Sophora alopecuroides 苦豆根 To clear intestines and dry damp, settle pain./Damp-heat dysentery, enteritis and diarrhea, jaundice, eczema, sore pharynx, toothache, intractable lichen, scalds.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001092 苦豆草
TCMBANKHE001194 Herba Sophorae Alopecuroidis 苦甘草 1. To clear heat and toxic material, deprive dampness and kill parasites. For sorethroat, dysentery, trichomonas enteritis, toothache, stomachache and leucorrhagia, external use for tinea and eczema. 2. To relieve dyspnea and cough. 3. Anticarcinogenic. For malignant hydatidiform mole, chorionic epithelioma and leukemia./1. To clear heat and toxic material, deprive dampness and kill parasites. For sorethroat, dysentery, trichomonas enteritis, toothache, stomachache and leucorrhagia, external use for tinea and eczema. 2. To relieve dyspnea and cough. 3. Anticarcinogenic. F
TCMBANKHE003410 柔枝槐
TCMBANKHE003666 沙参槐
TCMBANKHE006167 Herba Corydalis bungeae 苦地丁 Influenza, infection of upper respiratory tract, tonsillitis, infective hepatitis, enteritis, dysentery, nephritis, parotitis, conjunctivitis, acute appendicitis, clove sore and swollen welling abscess, scrofula.
TCMBANKHE004613 flos Sophorae 槐花 To arrest bleeding by reducing heat in blood, and to quench excess fire in the liver./1. Its component rutin decreases capillay permeability. 2. Lowering blood pressure transiently in anesthetized dog. 3. Inhibiting the growth of various dermatomyces.
TCMBANKHE004838 Radix Sophorae Tonkinensis 山豆根 To remove toxic heat, promote the subsidence of swelling, and soothe the sore throat./Septicemia, ulcer of uterine cervix, chronic cervicitis, bacillary dysentery, enteritis, hydatid moles, chorioblastoma, asthma, chronic bronchitis, acute tonsillitis, laryngitis, accumulated fire toxin, swelling pain in throat, gingiva painful swelling.
TCMBANKHE008498 fructus Sophorae 槐角 For cooling blood and stopping bleeding
TCMBANKHE007521 Sophora alopecuroides 苦豆子 To clear heat and dry damp, kill worms and relieve pain./Dysentery, stomachache, excessive leukorrhea, eczema, sore and boil, intractable lichen.
TCMBANKHE008503 Radix Sophorae flavescentis 苦参 To remove heat and damp, to kill parasites, and to cause diuresis./Arrhythmia, otitis media, acute conjunctivitis, chronic conjunctivitis, trichomoniasis, septicemia, edema, damp-heat diarrhea, intestinal wind bleeding, acute jaundice, inhibited urination, vaginal discharge, pudendal itch, scab and lichen, leprosy, itchy skin, eczema, damp toxin sore, suppurative nest sore.
TCMBANKHE008328/YEM-99 Sophora flavescens [Syn. Sophora angustfolia]|Sophora flavescens Ait. 苦参实|苦参 苦参 云南民族药物志:第一卷 To clear heat and resolve toxin, free stool, kill worms./Acute bacillary dysentery, constipation, ascariasis. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE006936/YEM-99 Sophora flavescens [Syn. Sophora angustfolia]|Sophora flavescens Ait. 苦参实|苦参 苦参 云南民族药物志:第一卷 To clear heat and resolve toxin, free stool, kill worms./Acute bacillary dysentery, constipation, ascariasis. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000018 Pancreatic Neoplasm disease Digestive System Diseases; Neoplasms; Endocrine System Diseases 28893319

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000818 ROS1 MCF3; ROS; c-ros-1 ROS proto-oncogene 1, receptor tyrosine kinase
TCMBANKGE001085 MAPK8 JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c mitogen-activated protein kinase 8
TCMBANKGE001153 EPHB2 BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 EPH receptor B2
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1