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Compound Summary

Compound Information

TCMBANKIN036867

药名:	glycyrrhetinic acid
别名:	beta-Glycyrrhetic acid; glycyrrhetinicacid; 3-hydroxy-11-oxoolean-12-en-29-oate; (2S,4aS,6aS,6bR,10S,12aS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid; LT00233150; Glycyrrhetic acid; Glycyrrhetinic; 3b-hydroxy-11-oxo-Olean-12-en-30-oic acid; 3-hydroxy-11-oxoolean-12-en-29-oic acid (ACD/Name 4.0); 18b-Glycyrrhetic acid; Glycyrrhetin; Glycyrrhetinate; 3b-Hydroxy-11-oxoolean-12-en-30-oic acid; 18b-Glycyrrhtinic acid; Biosone; 3b-Hydroxy-11-oxoolean-12-en-30-oate; 3-Glycyrrhetinic acid; SCHEMBL13144257; 18b-Glycyrrhetinic acid; NCGC00186652-01; 3b-hydroxy-11-oxo-Olean-12-en-30-oate; b-glycyrrhetic acid; (2S,4AS,6AS,6BR,10S,12AS)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-3,4,5,6,7,8,8A,10,11,12,12B,14B-DODECAHYDRO-1H-PICENE-2-CARBOXYLIC ACID; a-glycyrrhetinic acid
分子式:	C30H46O4
Smiles:	CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C
成分:	HBIN028184
CAS_id:	471-53-4
SymMap_id:	SMIT01696;SMIT02479
TCMID_id:	23291;8840
PubChem_id:	18526330

化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000312	Radix Glycyrrhizae Preparata	炙甘草			Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE000541		甘草头
TCMBANKHE000702	Radix Glycyrrhizae Praeparata	炙草			Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE001300		制军炭
TCMBANKHE001384	Radix Glycyrrhizae uralensis	甘草稍
TCMBANKHE003349		甘草节
TCMBANKHE003728	Radix Glycyrrhizae	甘草			To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE003854	Glycyrrhiza aspera	粗毛甘草			See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis.
TCMBANKHE004528	Glycyrrhiza kansuensis	黄甘草			See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis.
TCMBANKHE006338	Glycyrrhiza glabra	光果甘草			See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis .
TCMBANKHE008131	Herba Abri	鸡骨草			To remove toxic heat, and to relieve the depressed liver and alleviate pain./Icterohepatitis, stomachache, wind-damp bone pain, stasis pain from knocks and falls, mammary welling abscess.
TCMBANKHE007546	Glycyrrhiza inflata	胀果甘草			See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis.
TCMBANKHE005918	Glycyrrhiza yunnanensis	云南甘草			See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis.
TCMBANKHE008626	Cortex Lycii Radicis	地骨皮			To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung./1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect.
TCMBANKHE007721	Exocarpium Benincasae	冬瓜皮			1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.

植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI009429	Sarcoma	group	Neoplasms	28933787

化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE000844	CYP2E1	CPE1; CYP2E; P450-J; P450C2E	cytochrome P450 family 2 subfamily E member 1
TCMBANKGE006866	HSD11B2	AME; AME1; HSD11K; HSD2; SDR9C3	hydroxysteroid 11-beta dehydrogenase 2