Compound Summary


  Compound Information

药名:

diosmin

别名:

520-27-4; C10039; 5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chromen-4-one; 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.- D-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-; Diosmin [INN]; Diosmetin 7-O-rutinoside; AIDS059330; Diosmine [INN-French]; 5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxan-2-yl]oxy-chromen-4-one; Diosminum [INN-Latin]; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-tetrahydropyranyl]oxymethyl]-2-tetrahydropyranyl]oxy]-4-chromenone; AIDS-059330; Diosmin [INN-Spanish]; 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-; 5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chromone; CCRIS 7915; SMP1_000183; EINECS 208-289-7; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one; D3908; diosmin ; Diosmin; STOCK1N-14729

分子式:

C28H32O15

Smiles:

CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O

成分:

HBIN024193

SymMap_id:

SMIT01384;SMIT06901

TCMID_id:

6453

TCMSP_id:

MOL005093

PubChem_id:

5281613


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000810 Radix Zanthoxyli 两面针 To promote the flow of qi, relieve pain, to eliminate blood stasis, to promote blood circulation and dispel wind./Treatment of traumatic injury, rheumatic arthralgia, stomach-ache, teethache, bitten by venomous snake, applied for burn caused by hot liquid or fire.
TCMBANKHE002350 芫荽
TCMBANKHE002645 Salvia tomentosa
TCMBANKHE003718 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE003724 Rhizoma Curcumae longae 姜黄 To eliminate blood stasis, promote the flow of qi, stimulate menstrual discharge and relieve pain./Gallstones, jaundice, leukaemia in early stage and carcinoma of uterine cervix in early stage, chronic ulcer, chronic scab, blood stasis and qi stagnation, pain in chest and abdomen and rib-side, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, wind-heat impediment pain, knocks and falls, swollen welling abscess.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003843 Citrus limon 柠檬 To engender liquid and allay thirst, dispel summerheat, quiet fetus./Stomach heat fluid damage, summerheat stroke with vexation and thirst, inappetence, glomus distention in stomach duct and abdomen, lung heat dry cough, vomiting in pregnancy.
TCMBANKHE005793 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE005787 Sophora viciifolia 白刺花 To clear heat and disinhibit throat, cool blood and disperse swelling./Swelling pain in throat, cough, hepatitis, dysentery, strangury syndrome, edema, hematuria, nosebleed(epistaxis), hematochezia.
TCMBANKHE008552 Herba Capsellae 荠菜 1. Cool the blood and stop bleeding. 2. Clear away heat and promote diuresis. 3. Lower blood pressure./Blood ejection, spontaneous external bleeding, hemoptysis, hematuria, flooding and spotting, red eyes with gall, eyeground hemorrhage, hypertension, red and white dysentery, nephritis with edema, chyluria.
TCMBANKHE004374 Urtica cannabina 荨麻 To dispel wind and free network vessels, calm liver and settle fright, disperse accumulation and free stool, resolve toxin./Wind-damp impediment pain, postpartum wind tetany, infant fright wind, sequel of poliomyelitis, hypertension, indigestion, fecal stoppage, urticaria, knocks and falls, snake or insect bites.
TCMBANKHE004651 Medulla Junci 灯心草 To eliminate excess fire in the heart, and to induce diuresis./Strangury, edema, inhibited urination, damp-heat jaundice, insomnia and vexation, infant night crying, throat impediment, mouth sore, wound.
TCMBANKHE006554 Radix Sanguisorbae 地榆 To arrest bleeding by dispelling heat for blood, and to counteract toxicity and cure sores./Blood ejection, hemoptysis, duodenal ulcer, spontaneous external bleeding, hematuria, hematochezia, bleeding from hemorrhoids, blood dysentery, flooding and spotting, red and white vaginal discharge, swelling pain of welling abscess and sore, eczema, pudendal itch, burns and scalds, snake or insect bites.
TCMBANKHE005000 Pericarpium Zanthoxyli 花椒 To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE005016 Scabiosa caucasica 高加索蓝盆花
TCMBANKHE005043 herba pyrolae chinensis 鹿衔草 To relieve rheumatic conditions, to strengthen the tendons and bones, and to arrest bleeding./Pulmonary infection, intestinal infection, urinary tract infection, infant diarrhea, acute dysentery, wind-damp impediment pain, lassitude in lumbus and knees, profuse menstruation, enduring cough.
TCMBANKHE005186 Scabiosa comosa 蒙古山萝卜 To clear heat and drain fire./Lung heat cough asthma, liver fire headache, red eyes, damp-heat jaundice.
TCMBANKHE006232 Fructus Citri sarcodactylis 佛手 To regulate the qi of the liver and stomach, and relieve pain./Stomachache, distention in rib-side, vomiting, dysphagia-occlusion, phlegm-rheum cough asthma.
TCMBANKHE005694 Scrophularia nodosa 铃声玄参;林生玄参
TCMBANKHE006286 Galium aparine 八仙草 To clear damp heat, dissipate stasis, disperse swelling, resolve toxin./Strangury-turbidity, hematuria, knocks and falls, intestinal welling abscess, swollen boil, otitis media.
TCMBANKHE005929 Radix et Rhizoma Notopterygii 羌活 To relieve pain and rheumatic conditions./Externally contracted wind-cold, headache without sweating, wind-cold-damp impediment, edema, toxin swelling of sores.
TCMBANKHE006702 Capsella bursa- pastoris 荠菜子 To dispel wind and brighten eyes./Eye pain, eye screen, clear-eye blindness.
TCMBANKHE008203 Citrus limon 柠檬皮 To soothe stagnation and move qi, fortify stomach and relieve pain./Blood stasis and abdominal pain, menstrual disorder, no thought of food and drink.
TCMBANKHE006349 Zanthoxylum avicennae 鹰不泊 To dispel wind and transform damp, disperse swelling and free network vessels./Swelling pain in throat, yellow swelling, malaria, wind-damp bone pain, contusion from knocks and falls.
TCMBANKHE007829 Pericarpium Zanthoxyli 花椒 To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE004944/XU-432 Taraxacum officinale 药用蒲公英 湖北省恩施州板桥镇
TCMBANKHE005271/YNS-173/XU-59 Rosmarinus officinalis|Rosmarinus officinalis Linn.|Rosmarinus officinalis L. 迷迭香 迷迭香 云南药材标准:第四册|云南省昆明市盘龙区 祛风解表,健脾和胃,理气止痛。用于外感头痛,头风痛, 饮食积滞,脘腹胀痛|To effuse sweat, fortify spleen, quiet spirit, relieve pain./Headache, prevention of hair loss in early stage.
TCMBANKHE005980/YEM-13 herba Menthae;Mentha haplocalyx Briq|Mentha haplocalyx Briq. 薄荷 薄荷 云南民族药物志:第一卷 To dispel wind-heat from the head and eyes, and to promote eruption./Chronic urticaria, infection of upper respiratory tract, sarcoma, wind-heat exterior syndrome, headache and red eyes, swelling pain in throat, non-eruption of measles, dormant papules with pruritus, liver depression and rib-side pain, abdominal distention. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE003964/YEM-214/XU-446 Zanthoxylum nitidum|Zanthoxylum nitidum (Roxb.)DC 入地金牛|两面针 两面针 云南民族药物志:第二卷|广东省廉江市石岭镇 To dispel wind and free network vessels, disperse swelling and relieve pain./Wind-damp bone pain, stomachache, toothache, throat impediment, scrofula, burns and scalds. 傣族/哈尼族
TCMBANKHE008071/YEM-274 Spora Lygodii|Lygodium japonicum(Thunb.)Sw. 海金沙 海金沙 云南民族药物志:第二卷 To promote diuresis and treat stranguria/Heat strangury, stone strangury, blood strangury, inhibited urination [=dysuria], edema, white turbidity, vaginal discharge, hepatitis, diarrhea, dysentery, common cold with fever, cough and asthma, swelling pain in throat, mouth sore, red eyes with gall, mumps, mammary welling abscess, erysipelas, zoster, burns and scalds, itchy skin, wound swelling from knocks and falls, wind-damp impediment pain, bleeding due to external injury. 阿昌族/白族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/彝族/藏族
TCMBANKHE005663/YNS-73/YEM-663 Toddalia asiatica|Toddalia asiatica (L.) Lam.|Toddalia asiatica(L.)Lam. 飞龙掌血 飞龙掌血茎|飞龙掌血 云南药材标准:第四册|云南民族药物志:第四卷 活血止痛,祛风散寒。用于胃脘疼痛;腰痛,寒湿痹痛,跌倒损伤;皮肤瘙痒|To dispel wind and relieve pain, stanch bleeding and dissipate stasis./Wind-damp Pain, stomachache, knocks and falls, blood ejection, spontaneous external bleeding, knife wound, amenorrhea, dysmenorrhea. 阿昌族/布依族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/佤族/瑶族/彝族/壮族
TCMBANKHE007056/YEM-9 Herba Lobeliae Chinensis|Lobelia chinensis Lour. 半边莲 半边莲 云南民族药物志:第一卷 To cause diuresis, and to remove toxic heat./Edema, edema and enlarged abdomen, edema in face and foot, swollen welling abscess and clove sores, snake or insect bites. 阿昌族/傣族/德昂族/景颇族/傈僳族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000085 Inflammation phenotype Pathological Conditions, Signs and Symptoms 26361726
TCMBANKDI029884 Acute Lung Injury disease Respiratory Tract Diseases 26361726

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000051 IL1B IL-1; IL1-BETA; IL1F2; IL1beta interleukin 1 beta
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000053 NFKB1 CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB nuclear factor kappa B subunit 1
TCMBANKGE000240 IL17A CTLA-8; CTLA8; IL-17; IL-17A; IL17 interleukin 17A
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001161 IL2 IL-2; TCGF; lymphokine interleukin 2