Compound Summary


  Compound Information

药名:

paeoniflorin

别名:

Paeoniflorin; 23180-57-6; C09959; paeoniflorin ; AIDS-002238; AIDS002238; AKOS015962161; AC-15908; .beta.-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl

分子式:

C23H28O11

Smiles:

CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O

成分:

HBIN038606

OB_score:

53.870375

CAS_id:

23180-57-6

SymMap_id:

SMIT00129

TCMID_id:

16514

TCMSP_id:

MOL001924

PubChem_id:

442534


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001001 Paeonia lactiflora wild To clear heat and cool blood, quicken blood and dispel stasis./Warm toxin macular eruption, blood ejection, spontaneous external bleeding, intestinal wind bleeding, red eyes with gall, swollen welling abscess and sores, amenorrhea, dysmenorrhea, flooding and vaginal discharge with strangury-turbidity, pain in rib-side due to stagnation, mounting-conglomeration accumulation-gathering, knocks and falls.
TCMBANKHE004858 白毛藤 Malaria, jaundice, edema, strangury, pain in joints due to rheumatalgia, erysipelas, clove sore.
TCMBANKHE003237 毛果芍药
TCMBANKHE003717 fructus Capsici 辣椒 See Capsicum annuum.
TCMBANKHE003753 Borneolum syntheticum 冰片 1. To open the orifices and clear the mind; 2. To clear heat and stop pain/Angina pectoris, phlegm reversal, wind stroke, coma, convulsion, swelling pain in throat, mouth sore, swollen and painful eyes, sores, ulcer.
TCMBANKHE003826 Rhizoma Cimicifugae 升麻 To induce perspiration and promote eruption, to remove toxic heat, and to cure drooping and ptosis./Prevention of ptosis, women’s hormone dysfunction diseases, seasonal epidemic fire toxin, mouth sore, sore pharynx, macula, cold-heat headache, swelling toxin of welling abscess and sore, center qi fall, spleen vacuity diarrhea, chronic dysentery, vaginal discharge, flooding.
TCMBANKHE003883 Paeonia obovata 草芍药 See Paeonia lactiflora wild./See Paeonia lactiflora wild.
TCMBANKHE004244 Radix Paeoniae Alba 白芍 1. To nourish blood and consolidate the yin; 2. To pacify the liver and stop pain; 3. To soothe liver yang/Headache and dizziness, pain in rib-side, abdominal pain, spasm in limbs, anemia with yellow complexion, menstrual disorder, profuse menstruation, spontaneous sweating, night sweating.
TCMBANKHE004245 Radix Paeoniae Alba 杭芍 Treatment of headache and dizziness, costal and abdomina pain, spasmodic pain of the limbs, anemia, menstrual disorders, spontaneous sweating and night sweating./1. Dilating the coronary artery and blood vessels of hind legs in dogs. 2. Lowering blood pressure transiently. 3. Inhibiting the intestines in rabbits in vitro. 4. Its component paeoniflorin inhibits the central nervous systems.
TCMBANKHE004609 白芍药
TCMBANKHE004707 Radix Paeoniae Rubra; Lignum Paeoniae Rubra 赤芍 To remove heat from blood, to eliminate blood stasis, and to relieve pain./1. Paeoniflorin, one of its active components, has a strong antispastic effect and also analgesic, sedative, anticonvulsive, antibacterial and anti-imflammatory effects. 2. Dilating blood vessels, increasing coronary flow and improving myocardial oxygen supply. 3. Inhibiting platelets aggregation.
TCMBANKHE005206 赤芍药
TCMBANKHE007110 Semen Citri Reticulatae 橘核 To regulate the flow of qi, cause subsidence of modulation, and relieve pain./Mounting qi, painful swollen testes, mammary welling abscess, lumbago, bladder qi pain.
TCMBANKHE007893 Paeonia veitchii 川赤芍 See Paeonia lactiflora wild./See Paeonia lactiflora wild.
TCMBANKHE006209 Rhizoma Atractylodis 苍术 To remove damp and invigorate the function of the spleen, to disple wind-cold, and to improve eyesight./Spleen-stomach damp turbidity, fatigue hypodynamia, glomus in chest, abdominal distention, inappetence, vomiting and diarrhea, phlegm-rheum, damp edema, exterior damp, heavy head and generalized pain, damp impediment, aching pain in limbs, crippling wilt, night blindness.
TCMBANKHE008919 Paeonia officinalis 药用牡丹
TCMBANKHE006566 Cortex Moutan 牡丹皮 To remove heat from blood, to activate blood circulation and eliminate blood stasis./Appendicitis, dysentery, hypertension, allergic rhinitis, warm heat disease with fever, macular eruption, blood ejection, spontaneous external bleeding, steaming bone tidal fever due to yin vacuity, amenorrhea due to blood stasis, dysmenorrhea, concretion and conglomeration, swelling toxin of welling abscess and sore, painful wound from knocks and falls, wind-damp-heat impediment.
TCMBANKHE006671 白及 Hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, bleeding due to external injury, swelling toxin of welling abscess and sore, burns and scalds, cracking of hands and feet, splitting of anus.
TCMBANKHE008662 Radix Paeoniae Alba 白芍 1. To nourish blood and consolidate the yin; 2. To pacify the liver and stop pain; 3. To soothe liver yang/Headache and dizziness, pain in rib-side, abdominal pain, spasm in limbs, anemia with yellow complexion, menstrual disorder, profuse menstruation, spontaneous sweating, night sweating.
TCMBANKHE006081/YNS-308/YEM-70 Paeonia delavayi|Paeonia delavayi Franch|Paeonia delavayi Franch. var. lutea (Delavayex Franch.)Finet et Gagn. 滇牡丹|黄牡丹 云赤芍/云丹皮|黄牡丹 云南药材标准:第七册|云南民族药物志:第一卷 泻肝火、散恶血。用于瘀血腹痛、胁痛,血痹,癥瘕,肠风下血,痈肿,目赤,经闭。/通经凉血,散瘀止血、止痛。用于吐血,尿血,血痢,腹痛,骨蒸劳热,血瘀经闭,痛经。|See Paeonia moutan ./See Paeonia moutan. 藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000002 Hyperalgesia phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases 30975172
TCMBANKDI000003 Encephalitis disease Nervous System Diseases 30975172
TCMBANKDI000085 Inflammation phenotype Pathological Conditions, Signs and Symptoms 29017971
TCMBANKDI001795 Reperfusion Injury disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 31181335
TCMBANKDI006012 Neuralgia phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases 30975172
TCMBANKDI025576 Pain, Postoperative phenotype Pathological Conditions, Signs and Symptoms 29017971
TCMBANKDI030535 Sciatic Neuropathy disease Nervous System Diseases 30975172

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000051 IL1B IL-1; IL1-BETA; IL1F2; IL1beta interleukin 1 beta
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000053 NFKB1 CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB nuclear factor kappa B subunit 1
TCMBANKGE000199 ICAM1 BB2; CD54; P3.58 intercellular adhesion molecule 1
TCMBANKGE000805 SOCS3 ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3 suppressor of cytokine signaling 3
TCMBANKGE000806 HSPA4 APG-2; HEL-S-5a; HS24/P52; HSPH2; RY; hsp70; hsp70RY heat shock protein family A (Hsp70) member 4
TCMBANKGE001027 STK11 LKB1; PJS; hLKB1 serine/threonine kinase 11
TCMBANKGE001083 MAP3K5 ASK1; MAPKKK5; MEKK5 mitogen-activated protein kinase kinase kinase 5
TCMBANKGE001085 MAPK8 JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c mitogen-activated protein kinase 8
TCMBANKGE001112 PRKAB1 AMPK; HAMPKb protein kinase AMP-activated non-catalytic subunit beta 1
TCMBANKGE001127 PRKAA1 AMPK; AMPKa1 protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE001128 PRKAA2 AMPK; AMPK2; AMPKa2; PRKAA protein kinase AMP-activated catalytic subunit alpha 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14