Compound Summary

  Compound Information

TCMBANKIN036902

药名:	magnolol
别名:	UPCMLD-DP037:001; UNII-001E35HGVF; 001E35HGVF; TR-031540; FT-0628104; SR-01000758206-3; AN-15430; 2'-Bichavicol; NSC 293099; MLS001048917; STK801955; KS-000009BG; ZINC00001645; [1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propenyl-; 5,5'-bis(prop-2-en-1-yl)-[1,1'-biphenyl]-2,2'-diol; HMS3651O18; ZINC1645; PubChem19035; DS-1284; CTK1G9448; ST24029219; NCGC00161609-01; 2-(2-hydroxy-5-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol; 5,5'-Di-2-propenyl-[1,1'-biphenyl]-2,2'-diol; HY-N0163; BN0720; 2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphenol; MFCD00016658; SMP2_000086; SCHEMBL132477; 5,5'-Diallyl-2,2'-dihydroxybiphenyl; (1,1'-Biphenyl)-2,2'-diol, 5,5'-di-2-propenyl-; 3r5n; BC205200; Magnolol, European Pharmacopoeia (EP) Reference Standard; NSC293099; Magnolol, >=95% (HPLC), from plant; ACN-035415; SMR000387108; CM0085; Magnolol; NCGC00161609-02; magnolol ; MCULE-1351244567; AB0016717; VVOAZFWZEDHOOU-UHFFFAOYSA-N; 4-allyl-2-(5-allyl-2-hydroxy-phenyl)phenol; 2-[2-hydroxy-5-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol; 5,5'-Diallyl-[1,1'-biphenyl]-2,2'-diol; 2-(2-oxidanyl-5-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol; 528-43-8; 4-allyl-2-(5-allyl-2-hydroxyphenyl)phenol; HMS2269N09; Dehydrodichavicol; AC1Q7B1V; 4CN-0760; D3971; 5,5′-Diallyl-2,2′-biphenyldiol; BBL027818; s2321; 5,5'-Diallylbiphenyl-2,2'-diol; NSC-293099; KB-279770; CHEMBL180920; CCG-208588; AJ-08064; S-2836; 5,5'-Diallyl-2,2'-biphenyldiol; 5,5'-di(prop-2-en-1-yl)biphenyl-2,2'-diol; SR-01000758206; HSDB 7686; DTXSID0044076; AIDS-002239; BR-72952; CHEBI:6643; SC-25620; J10186; 5,5;-Diallyl-[1,1;-biphenyl]-2,2;-diol; M3445_SIGMA; UPCMLD-DP037; 528M438; BDBM78304; I01-2281; O906; Q-100598; AX8016874; LS-44356; AIDS002239; 2,2'-Bichavicol; BG00615874; Kopnolia; AC-931; N1359; SR-01000758206-4; AK-72952; MolPort-002-507-434; BB_NC-1463; Bio-0675; BRD-K26168087-001-01-4; RTR-031540; AKOS005266409; ZB000381; REGID_for_CID_72300; cid_72300; C-16714; C10651; AC1L2HT7; SY016075; CC-30123; CJ-00060; CS-5021
分子式:	C18H18O2
Smiles:	C([H])([H])=C([H])C([H])([H])c1c([H])c([H])c(O[H])c(c2c([H])c(C([H])([H])C([H])=C([H])[H])c([H])c([H])c2O[H])c1[H]
成分:	HBIN034250
CAS_id:	528-43-8
SymMap_id:	SMIT01500;SMIT02857
TCMID_id:	13381
TCMSP_id:	MOL000210
PubChem_id:	72300

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE006453	Fructus Momordicae	罗汉果			To remove heat, moisten the lung and relax the bowels./Lung heat dry cough, common cold, throat pain, laryngitis, aphonia due to throat pain, intestinal dry and constipation.
TCMBANKHE003858	Semen Strychni Praeparata	炙马钱子			Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores./Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores.
TCMBANKHE004198	Magnolia biondii [Syn. Magnolia fargesii]	望春玉兰			See Magnolia liliflora./See Magnolia liliflora.
TCMBANKHE004608	Magnolia grandiflora	荷花玉兰			To dispel wind and dissipate cold, move qi and relieve pain./Externally contracted wind-cold, headache and nasal congestion, distending pain in stomach duct, vomiting and diarrhea, hypertension, tuberculosis.
TCMBANKHE009013	Cortex Illicii	地枫皮			To relieve rheumatic conditions, and to promote the flow of qi and relieve pain./Pain in joints due to rheumatalgia, taxation damage in lumbar muscle, centipede bite.
TCMBANKHE004771	Magnolia obovata	日本厚朴
TCMBANKHE005168		辛夷			Wind-cold common cold, headache, nasal congestion and runny nose, nasitis, nasosinusitis.
TCMBANKHE005338	Sassafras randainense	台湾檫木
TCMBANKHE007292		藁本			Headache due to externally contracted wind-cold, vertex headache, pain in tooth and cheek, migraine, wind-cold-damp impediment, pain in limbs.
TCMBANKHE005228/YEM-235	Cortex Magnoliae officilis;Magnolia officinalis|Magnolia officinalis Rehd.et Wils.	厚朴	厚朴	云南民族药物志：第二卷	To eliminate damp and relieve distension;To dry damp and disperse phlegm, precipitate qi and eliminate fullness, lower blood pressure./1. Broad-spectrum antibacterial.2. Magnocurarine, one of the active components, can relaxstriated muscles.3. Its decoction stimulates the smooth muscles of intestines and bronchii in rabbits in vitro.4. Magnocuraine may also lower blood pressure and accelerate heart rate.5.Amebic dysentery, vomiting and diarrhea, food accumulation and qi stagnation, abdominal distention and constipation, phlegm-rheum cough asthma.	彝族
TCMBANKHE007340/YEM-235	Flos Magnoliae Offcinalis|Magnolia officinalis Rehd.et Wils.	厚朴花|厚朴	厚朴	云南民族药物志：第二卷	Treatment of feeling of stuffiness and distension in the chest and epigastrium with loss of appetite./Treatment of feeling of stuffiness and distension in the chest and epigastrium with loss of appetite.	彝族
TCMBANKHE002025/YEM-235	Magnoliae Officinalis Praeparata|Magnolia officinalis Rehd.et Wils.	炙厚朴|厚朴	厚朴	云南民族药物志：第二卷	Treatment of accumulation of damp in the spleen and the stomach marked by epigastric strffiness, vomiting and diarrhea, abdominal distension and constipation due to retention of undigested food, cough and dyspnea caused by retanied damp./1. Broad-spectrum antibacterial.2. Magnocurarine, one of the active components, can relaxstriated muscles.3. Its decoction stimulates the smooth muscles of intestines and bronchii in rabbits in vitro.4. Magnocuraine may also lower blood pressure and accelerate heart rate.	彝族
TCMBANKHE004240/YEM-586	Magnolia rostrata|Magnolia rostrata W.W.Sm.	大叶厚朴|长喙厚朴	贡山厚朴	云南民族药物志：第三卷	To warm center and transform damp, move qi and disperse accumulation./Distention fullness and sudden pain in chest and abdomen, food accumulation and qi stagnation, vomiting, diarrhea, cough with profuse phlegm.	傈僳族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000047	Neoplasm Metastasis	phenotype	Pathological Conditions, Signs and Symptoms; Neoplasms	21757288
TCMBANKDI000085	Inflammation	phenotype	Pathological Conditions, Signs and Symptoms	30597199
TCMBANKDI000088	Lung Neoplasms	group	Neoplasms; Respiratory Tract Diseases	27268146
TCMBANKDI003733	Cerebral Hemorrhage	phenotype	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases	30597199
TCMBANKDI015773	Brain Edema	phenotype	Nervous System Diseases	30597199
TCMBANKDI025605	Seizures	phenotype	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	21518336
TCMBANKDI026887	ovarian neoplasm	disease	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases	21757288
TCMBANKDI031985	Brain Ischemia	disease	Nervous System Diseases; Cardiovascular Diseases	30597199

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000162	MMP13	CLG3; MANDP1; MDST; MMP-13	matrix metallopeptidase 13
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000248	MMP10	SL-2; STMY2	matrix metallopeptidase 10
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000389	MMP3	CHDS6; MMP-3; SL-1; STMY; STMY1; STR1	matrix metallopeptidase 3
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000514	CNR1	CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR	cannabinoid receptor 1
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000753	CNR2	CB-2; CB2; CX5	cannabinoid receptor 2
TCMBANKGE000787	VCAM1	CD106; INCAM-100	vascular cell adhesion molecule 1
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000935	S100B	NEF; S100; S100-B; S100beta	S100 calcium binding protein B
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000986	ERBB2	CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1	erb-b2 receptor tyrosine kinase 2
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001118	MMP9	CLG4B; GELB; MANDP2; MMP-9	matrix metallopeptidase 9
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001197	FOS	AP-1; C-FOS; p55	Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001697	MMP1	CLG; CLGN	matrix metallopeptidase 1
TCMBANKGE001755	MAOB	-	monoamine oxidase B
TCMBANKGE001943	ADRA1D	ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2	adrenoceptor alpha 1D
TCMBANKGE003625	SLC6A4	5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT	solute carrier family 6 member 4
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006943	CHRM3	EGBRS; HM3; PBS	cholinergic receptor muscarinic 3
TCMBANKGE008048	SLC5A7	CHT; CHT1; CMS20; HMN7A	solute carrier family 5 member 7
TCMBANKGE008397	MMP27	MMP-27	matrix metallopeptidase 27
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE009256	SLC6A2	NAT1; NET; NET1; SLC6A5	solute carrier family 6 member 2
TCMBANKGE009373	MMP8	CLG1; HNC; MMP-8; PMNL-CL	matrix metallopeptidase 8
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE012155	SLC6A3	DAT; DAT1; PKDYS; PKDYS1	solute carrier family 6 member 3
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1