Compound Summary


  Compound Information

药名:

isovitexin

别名:

beta-D-isovitexin; LMPK12110338; Iso Vitexin; CHEBI:18330; 61383-34-4; C01714; 61838-34-4; 29702-25-8; 6-beta-D-Glucopyranosyl-4',5,7-trihydroxyflavone; 4H-1-Benzopyran-4-one, 6-beta-D-glucopyranosyl-5,7- dihydroxy-2-(4-hydroxyphenyl)-; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]-4-chromenone; 6-Glucosylapigenin; Isovitexin; Apigenin-6-C-glucoside; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]chromone; Apigenin 6-C-glucoside; 38953-85-4; NCGC00163578-01; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one; Saponaretin; 4H-1-Benzopyran-4-one, 6-beta-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)- (VAN); AIDS339232; (1S)-1,5-anhydro-1-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one; 6-C-Glucosylapigenin; AIDS-339232

分子式:

C20H18O10

Smiles:

c1(C2=C([H])C(=O)c(c(O[H])c([C@@]3([H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]([H])(O[H])O3)c(O[H])c4[H])c4O2)c([H])c([H])c(O[H])c([H])c1[H]

成分:

HBIN031346

OB_score:

31.294643

CAS_id:

61838-34-4

SymMap_id:

SMIT00495

TCMID_id:

38232;11770

TCMSP_id:

MOL002322;MOL011111

PubChem_id:

162350


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000392 Vitex littoralis
TCMBANKHE000903 甜瓜皮
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001333 Semen Cucumis 甜瓜子
TCMBANKHE001533 生瓜
TCMBANKHE001546 甜瓜叶
TCMBANKHE001778 甜瓜花
TCMBANKHE002475 Herba Nerviliae 青天葵 1. To clear heat and toxic material. For skin infection of intense heat type, sorethroat, summer-heat syndrome with fever and thirst, scrofula. 2. To moisturize the lung to relieve cough. For cough of heat type and dryness type./1. To clear heat and toxic material. For skin infection of intense heat type, sorethroat, summer-heat syndrome with fever and thirst, scrofula. 2. To moisturize the lung to relieve cough. For cough of heat type and dryness type.
TCMBANKHE003062 甜瓜根
TCMBANKHE003105 布渣叶
TCMBANKHE003495 甜瓜茎
TCMBANKHE003589 Tripterospermum japonicum 日本双蝴蝶茶花 See Tripterospermum taiwanense./See Tripterospermum taiwanense.
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE007156 Herba Patriniae 败酱草 1. To eliminate heat and toxic material, relieve abscess and promote pus drainage. 2. To remove blood stasis and alleviate pain/1. Two active components, patrinene and isopatrinene, possess sedative effect. 2. To promote regeneration of hepatic cells and portal circulation, protect hepatic cells from degernation and improve hepatic function.
TCMBANKHE003804 Swertia pseudochinensis 獐牙菜 To drain fire and resolve toxin, disinhibit damp, fortify spleen./Acute icterohepatitis, chronic liver diseases, damp-heat jaundice, dysentery, gastritis, indigestion, acute conjunctivitis, toothache, mouth sore, swelling pain of sores.
TCMBANKHE005470 Indigo turalis 青黛 To remove toxic heat, to reduce heat in blood, and to relieve convulsions./1. Inhibiting leukemia7212 and many other other tumors in experimental animals2. Enhancing the fuction of reticuloendothelial system in healthy mice and promoting phagocytosis of macrophage in mice with cancer.3. It may cause abdominal pain, diarrhea or bloody stools.
TCMBANKHE005497 Rhizoma Belamcandae 射干 To remove toxic heat, eliminate phlegm, and soothe the sore throat./Heat toxin and phlegm-fire stasis, swelling pain in throat, cough and asthma.
TCMBANKHE003938 Linum usitatissimum 亚麻 To calm liver, quicken blood./Liver wind headache, knocks and falls, swollen welling abscess and clove sores.
TCMBANKHE005846 青葙子 1. Hypotensive2. Celosiaol, one of its active components is a mydriatic.
TCMBANKHE006326 Semen Vaccariae 王不留行 1. To invigorate blood and promote menstruation; 2. To promote lactation/Galactostasis, amenorrhea, dysmenorrhea, mammary welling abscess.
TCMBANKHE004791 Herba Spirodelae 浮萍 To dispel wind-heat, to promote eruption, and to cause diuresis./Wind-heat exterior syndrome, non-eruption of measles, dormant papules with pruritus, edema, dribbling urinary block, sore and lichen, erysipelas, scalds.
TCMBANKHE005102 Microcos paniculata [Syn. Grewia microcos ] 破布叶 To clear heat and disinhibit damp, fortify stomach and disperse stagnation./Common cold with fever, jaundice, inappetence, indigestion, distending pain in stomach duct and abdomen, diarrhea, sores, centipede bite.
TCMBANKHE007206 Lignum Santaii Albi 檀香 To promote the flow of qi in the heart, to warm the spleen and stomach, to increse appetite, and to relieve pain./Pain in chest and abdomen, cold stomachache, vomiting of water due to congealing cold qi stagnation, coronary heart disease with pattern of qi stagnation and blood stasis.
TCMBANKHE007523 Folium Polygoni Tinctorii 蓼大青叶 To remove toxic heat, and to cause subsidence of eruptions by reducing heat in blood./Treatment of fever and eruptions in epidemic diseases, cough and asthma due to heat in the lung, inflammation of the throat, mnmps, erysipelas, carbuncle.
TCMBANKHE005736 Herba Commelie 鸭跖草 1. Clear away heat and toxic materials. 2. Clear away heat and promote diuresis. /Common cold, wind-heat common cold, influenza, noninfectious fever, ardent fever incessant, ascites, edema, hordeolum, swelling pain in throat, scant urine with edema, heat strangury with inhibited pain, swollen welling abscess and toxin of clove.
TCMBANKHE005884 Linum usitatissimum To calm liver, quicken blood./Liver wind headache, knocks and falls, swollen welling abscess and clove sores.
TCMBANKHE006113 Vitex lucens 新西兰牡荆苷;新西兰牡荆
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE006480 Ulva pertusa 孔石莼 See Ulva lactuca./See Ulva lactuca.
TCMBANKHE007224 Tripterospermum taiwanense 台湾双蝴蝶 To clear heat and resolve toxin, suppress cough./Jaundice, wind-heat cough.
TCMBANKHE006580 Calycis Melo 瓜蒂 Vomiting promotion/Wind stroke, epilepsy, throat impediment, indigestion of overnight food, distending pain in stomach duct, damp-heat jaundice, chronic hepatitis, cirrhosis.
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE007176 Fagopyrum tataricum 苦荞麦
TCMBANKHE007551 Catechu 儿茶 To reduce toxic and to remove dampness./To arrest exudation, promote the growth of new tissue, and cure wounds.
TCMBANKHE005609/XU-345 Gleditsia sinensis [Syn. Gleditsia horrida]|Gleditsia sinensis 皂荚 云南省曲靖市会泽县 To relieve cough and dispel phlegm, open orifices, kill worms and dissipate binds./Cough of phlegm asthma, wind stroke clenched jaw, phlegm-drool and congesting lung, clouded spirit with loss of speech, epilepsy, throat impediment, urinary and fecal stoppage, swollen welling abscess, scab and lichen.
TCMBANKHE005494/YEM-445 Fructus Hordei Germitus|Hordeum vulgare L. 麦芽|大麦 大麦 云南民族药物志:第三卷 To invigo rate the function of the spleen, to regulate the function of the stomach, and to promote the flow of milk./Food accumulation, abdominal distention and diarrhea, nausea and vomiting, inappetence, galactostasis, distending pain in breast. 佤族/彝族
TCMBANKHE005333/YEM-568 Fagopyrum esculentum|Fagopyrum esculentum Moench 荞麦 甜荞 云南民族药物志:第三卷 To fortify spleen and disperse accumulation, precipitate qi and loosen intestines, resolve toxin and close sores./Gastrointestinal accumulation, diarrhea, dysentery, intestine gripping sand, white turbidity, vaginal discharge, spontaneous sweating, night sweating, zoster, erysipelas, effusion of back from welling abscess and flat abscess, scrofula, burns and scalds. 哈尼族/佤族/彝族
TCMBANKHE006147/YEM-616 Tamarindus indica|Tamarindus indica L. 酸角|酸豆 酸角 云南民族药物志:第三卷 To clear heat and resolve toxin, harmonize stomach and disperse accumulation./Summerheat stroke, inappetence, child gan accumulation, vomiting in pregnancy, constipation. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/佤族
TCMBANKHE004426/YEM-669 Cucumis sativus|Cucumis sativus L. 黄瓜 黄瓜 云南民族药物志:第四卷 To clear heat, disinhibit water, resolve toxin./Febrile diseases thirst, short voidings of reddish urine, burns and scalds, scant urine with edema, sweat macule, prickly heat. 傣族/哈尼族/佤族/彝族
TCMBANKHE008148/YEM-669 Cucumis sativus|Cucumis sativus L. 黄瓜 黄瓜 云南民族药物志:第四卷 To clear heat, disinhibit water, resolve toxin./Febrile diseases thirst, short voidings of reddish urine, burns and scalds, scant urine with edema, sweat macule, prickly heat. 傣族/哈尼族/佤族/彝族
TCMBANKHE000519/YEM-781 Drymaria diandra [Syn. Drymaria cordata ssp. diandra]|Drymaria diandra Bl. 二七狗牙花|荷莲豆 小野豌豆 云南民族药物志:第四卷 To clear heat and disinhibit damp, quicken blood and resolve toxin./Jaundice, edema, malaria, fright wind, leg qi due to wind-damp, toxin of sore welling abscess and boils, child gan accumulation, eye screen, outcrop. 哈尼族/佤族/彝族
TCMBANKHE005203/YEM-999/XU-341 Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica 板蓝根|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess. 回族/彝族
TCMBANKHE003869/YEM-999/XU-341 Folium Isatidis|Isatis indigotica Fort.|Isatis indigotica 板蓝根(大青叶)|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To clear heat and toxic materials, cool blood and eliminate eruption./Acute parotitis, encephalitis, hepatitis, lung abscess, acute gastroenteritis, infection of upper respiratory tract, warm evil in construction, ardent fever with clouded spirit, macular eruption and papules, jaundice, heat dysentery, epidemic parotitis, throat impediment, erysipelas, swollen welling abscess. 回族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI015496 Liver neoplasms group Digestive System Diseases; Neoplasms 31208440

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000999 FOXM1 FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT forkhead box M1
TCMBANKGE001047 E2F1 E2F-1; RBAP1; RBBP3; RBP3 E2F transcription factor 1
TCMBANKGE001076 SOD2 GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD superoxide dismutase 2