Compound Summary


  Compound Information

药名:

ecdysterone

别名:

2beta,3beta,14alpha,20beta,22,25-Hexahydroxy-7-cholesten-6-one; ZINC04165898; ST5412041; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; AIDS-013374; AIDS013374; CHEMBL1707235; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(1R,2R)-1,2,5-trihydroxy-1,5-dimethylhexyl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; HMS2225F24; SMR001397251; beta-Ecdysone; (2Beta,3beta,5beta)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one; H5142_SIGMA; 20-Hydroxyecdysone; SCHEMBL19213295; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methyl-heptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; 20-OH ecdysone; Ecdysterone; Insect moulting hormone; 20E; 2,3,14-Trihydroxy-10,13-dimethyl-17-(1,2,5-trihydroxy-1,5-dimethyl-hexyl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one; MLS002473159; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(1R,2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; (22R)-2beta,3beta,14alpha,20,22,25-hexahydroxy-5beta-cholest-7-en-6-one; 5289-74-7; CHEBI:16587

分子式:

C27H44O7

Smiles:

[C@@]1([H])(O[H])C([H])([H])[C@](C([H])([H])[H])([C@@]([H])(C([H])([H])C([H])([H])[C@](C([H])([H])[H])([C@@]([H])([C@@](C([H])([H])[H])(O[H])[C@]([H])(O[H])C([H])([H])C([H])([H])C(O[H])(C([H])([H])[H] )C([H])([H])[H])C([H])([H])C2([H])[H])[C@@]23O[H])C3=C([H])C4=O)[C@@]4([H])C([H])([H])[C@@]1([H])O[H]

成分:

HBIN024786

OB_score:

5.300587

CAS_id:

5289-74-7

SymMap_id:

SMIT00145

TCMID_id:

6678

TCMSP_id:

MOL002212

PubChem_id:

118701161


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004208 Thallus Lamiriae 昆布 To eliminate phlegm, soften hard masses and dissolve lumps, and to cause diuresis./Goiter and tuberculosis, scrofula, bleeding, painful swollen testes, phlegm-rheum and edema, prevention of cataracts.
TCMBANKHE000893 桑沥
TCMBANKHE001083 桑耳
TCMBANKHE001307 牛膝茎叶
TCMBANKHE001578 桑瘿
TCMBANKHE001635 桑柴灰
TCMBANKHE002046 金果揽 See Tinospora sagittata .
TCMBANKHE002080 桑叶汁
TCMBANKHE002548 桑根
TCMBANKHE002776 白花菜子 Wind-cold sinew and bone numbness, aching pain in back and shoulder, lumbago, swelling pain due to external injury, bone tuberculosis, hemorrhoids and fistulas.
TCMBANKHE003647 Polypodium vulgare To clear heat, resolve toxin and disinhibit damp./Damp-heat strangury pain, wind-damp-heat impediment, swollen welling abscess, sore and boil, wind papule itching, knocks and falls.
TCMBANKHE003681 Radix Aconiti Kusnezoffii 草乌 To relieve rheumatic conditions, to warm the channels and to alleviate pain./Treatment of rheumatic and rheumatoid arthralgia, precordial and abdominal pain with cold sensation, abdominal colic caused by cold, anaethesia.
TCMBANKHE003732 Ganoderma Lucidum seu Japonicum 灵芝(赤芝) Hyperlipemia, coronary heart disease, angina pectoris, septicemia, carcinoma, hepatitis, vacuity taxation, palpitation, insomnia, dizziness, fatigue hypodynamia, enduring cough and asthma, chronic bronchitis, silicosis.
TCMBANKHE003757 Matteuccia struthiopteris 小叶贯众 To clear heat and resolve toxin, kill worms, stanch bleeding./Febrile diseases macular eruption, parotitis, damp-heat sore toxin, abdominal pain due to ascariasis, oxyuria disease, red dysentery and bloody stool, hematuria, blood ejection, spontaneous external bleeding, flooding and spotting [=metrorrhagia and metrostaxis].
TCMBANKHE003911 Folium Sene 番泻叶 To purge feces downward/Heat bind and accumulation, constipation w ith abdominal pain, edema distention fullness.
TCMBANKHE003952 Folium Rhododendri Daurici 满山红 Acute bronchitis, chronic bronchitis.
TCMBANKHE003976 Periostracum Cicadae 蝉蜕 To dispel wind-heat, to soothe sore throat, to promote eruption, to clear the eye of corneal opacity, and to arrest spasm.;Treatment of upper respiratory infection with sore throat, hoarseness of voice, measles with inadequate eruption, urticaria with itching, inflammation of the eye with formation of corneal opacity, convulsion, tetanus./Treatment of upper respiratory infection with sore throat, hoarseness of voice, measles with inadequate eruption, urticaria with itching, inflammation of the eye with formation of corneal opacity, convulsion, tetanus.
TCMBANKHE004287 Radix Achyranthis bidentatae 牛膝 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat.
TCMBANKHE004377 Podocarpus imbricatus 鸡毛松
TCMBANKHE004523 Flos Gossampini 木棉花 Diarrhea, dysentery, hemoptysis, blood ejection, flooding, incised wound and bleeding, sore toxin, eczema.
TCMBANKHE004539 Fructus Kochiae 地肤子 To remove damp-heat, to dispel zvind, and to relieve itching./Inhibiting the growth of various dermatomyces in vitro.
TCMBANKHE004952 Lemmaphyllum microphyllum 螺厣草 To clear lung and relieve cough, cool blood and stanch bleeding, clear heat and resolve toxin./Lung heat cough, pulmonary welling abscess, hemoptysis, blood ejection, spontaneous external bleeding, hematuria, hematochezia, flooding and spotting, swelling pain in throat, parotitis, dysentery, scrofula, swelling toxin of welling abscess and sore, damp itchy skin, wind-fire toothache, wind-damp bone pain.
TCMBANKHE009190 Fructus Mori 桑椹 To nourish n and blood and promote the production of body fluid./Its contains sugar, organic acid , vitamins B1, B2 and C and carotene. Its oleum contains oleic acid and linoleic acid.
TCMBANKHE005116 Taxus cuspidata 紫杉 To disinhibit urine and free channels, anticancer./Kidney disease, diabetes mellitus, carcinoma of ovary, carcinoma of mammary glands.
TCMBANKHE005177 Pteridium aquilinum 欧洲蕨
TCMBANKHE005221 Semen Ginkgo 白果 1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE007439 Bombyx mori 白僵蚕 To dispel wind and resolve tetany, transform phlegm and dissipate binds, resolve toxin and disinhibit throat./Epilepsy, fright wind and convulsion, swelling pain in throat, acute infection of upper respiratory tract, epidemic parotitis, diabetes mellitus, temporomandibular lymphrnoditis, facial paralysis, itchy skin.
TCMBANKHE005577 Lychnis fulgens 大花剪秋罗 To clear heat and disinhibit urine, fortify spleen, quiet spirit./Inhibited urination, child gan accumulation, night sweating, headache, insomnia.
TCMBANKHE007604 Herba Glechomae Longitubae 金钱草 To remove damp-heat, relieve dysuria, and to promote subsidence of swelling./Increasing biliary secretion.
TCMBANKHE008359 Semen Oroxyli 木蝴蝶 To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE005747 Blechnum minus 小乌毛蕨
TCMBANKHE008485 Ajuga ciliata 筋骨草 To clear heat and resolve toxin, cool blood and disperse swelling./Swelling pain in throat, lung heat hemoptysis, painful swelling from knocks and falls.
TCMBANKHE006099 桑白皮 Lung heat cough asthma, water-rheum collecting lung, distention fullness and rapid asthma, edema, beriberi, inhibited urination.
TCMBANKHE007557 Herha Ajugae Ciliatae 白毛夏枯草 1. To clear lung-heat, eliminate phlegm and relieve cough. 2. to clear away heat and toxic material, and relieve carbuncle. 3. Clear away heat to cool the blood. 4. Lower blood pressure./Swelling pain in throat, lung heat cough, pulmonary welling abscess, red eyes with gall, dysentery, swollen welling abscess and clove sores, poisonous snake bite, knocks and falls.
TCMBANKHE006174 Trillium tschonoskii 延龄草 To calm, relieve pain, quicken blood, stanch bleeding./Hypertension, neurasthenia, dizziness and headache, pain in lumbus and legs, menstrual disorder [=menoxenia], flooding and spotting [=metrorrhagia and metrostaxis], bleeding due to external injury, knocks and falls.
TCMBANKHE008354 Semen Ginkgo 白果 1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE008355 Polypodium niponicum 水龙骨 To clear heat and disinhibit damp, quicken blood and free network vessels./Opacity of urine, diarrhea, strangury, wind-damp impediment pain, knocks and falls.
TCMBANKHE008615 Cyathula capitata 麻牛膝 To dispel wind-damp, expel stasis blood./Wind-cold-damp impediment, pain in lumbus and knees, amenorrhea due to blood stasis, postpartum persistent flow of lochia.
TCMBANKHE008697 Caulis Aristolochiae seu Clematis 木通 1. To promote water metabolism and relieve abnormal urination; 2. To clear heat and promote lactation/Acute urethritis, short voidings of reddish urine, strangury-turbidity, edema, nephritis with edema, galactostasis, heat vexation in chest, throat pain, mouth sore, tongue sores, wind-damp impediment pain, galactostasis, amenorrhea, dysmenorrhea.
TCMBANKHE006669 Radix Rhapontici 漏芦 To remove toxic heat for treating subcutaneous infections, to promote lactation, and to relieve muscular contracture./Mammary welling abscess, effusion of back from welling abscess and flat abscess, scrofula, galactostasis, damp impediment and hypertonicity.
TCMBANKHE007018 Bombyx mori 原蚕蛾 To supplement kidney and invigorate yang , rough essence, stanch bleeding, resolve toxin and disperse swelling./Impotence and emission, white turbidity, blood strangury, incised wound and bleeding, swelling pain in throat, mouth and tongue sores, swelling toxin of welling abscess and sore, frostbite, snake bite.
TCMBANKHE008310 Cortex Eucommiae 杜仲 To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy.
TCMBANKHE008092 Radix Cyathulae 川牛膝 To eliminate blood stasis and stimulate menstrual discharge, to allay arthralgia and ease the joint, and to relieve urinary disturbance./Amenorrhea with concretion and conglomeration, retention of placenta, impediment pain in joints, hematuria, blood strangury, knocks and falls.
TCMBANKHE008213/YEM-302/YEM-1017 Podocarpus macrophyllus|Podocarpus macrophyllus(Thunb.)D.Donvar.maki Endl. 罗汉松叶|短叶罗汉松 小叶罗汉松 云南民族药物志:第五卷 To stanch bleeding./Blood ejection, hemoptysis. 瑶族
TCMBANKHE008911/YEM-126 Radix Achyranthis bidentatae|Achyranthes bidentata Blume 牛膝;怀牛膝|牛膝 牛膝 云南民族药物志:第一卷 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward.Treament of soreness of the lumbar and knee joints with weakness inthe legs, amenorrhea with mass formation in the abdomen, dizziness due to hyperactivity of the liver./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE007228/YEM-159 Lepisorus thunbergianus|Lepisorus thunbergianus (Kaulf.)Ching 瓦苇|瓦韦 瓦韦 云南民族药物志:第一卷 To clear heat and resolve toxin, disinhibit urine and free strangury, stanch bleeding./Infant ardent fever, fright wind, swelling pain in throat, swollen welling abscess and sores, poisonous snake bite, dribbling and inhibited voidings of urination, hematuria, cough and hemoptysis. 阿昌族/傣族/景颇族/傈僳族/彝族
TCMBANKHE000209/YEM-208 Osmunda japonica|Osmunda japonica Thunb. 紫箕 紫箕贯众 云南民族药物志:第一卷 To clear heat and resolve toxin, dispel stasis and stanch bleeding, kill worms./Influenza, epidemic encephalitis, parotitis, swelling toxin of welling abscess and sore, measles papules, varicella, dysentery, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, vaginal discharge, intestinal parasitic disease. 傈僳族
TCMBANKHE004110/YEM-208 Rhizoma Dryopteris crassirhizomae|Osmunda japonica Thunb. 贯众|紫箕 紫箕贯众 云南民族药物志:第一卷 1. To clear heat and toxic material. For preventing and treating pestilence and seasonal febrile diseases, such as influenza, epidemic cerebrospinal meningitis, mumps, measles, etc., also for viral pneumonia. 2. To cool the blood nad stop bleeding. For profuse uterine bleeding due to blood-heat, hematemesis, epistaxis, hemafacia, eruptive diseases, etc.3. To kill parasites/1.Antivirotic and bacteriostatic. 2. Parasiticidal effect on hookworm, roundworm and whipworm, etc. in human, and its component filmarone, on tapeworm. 3. Its decoction shortens the blood clotting time in rabbits. 4. Its extract exerts an abortive effect. 傈僳族
TCMBANKHE006969/YEM-240 Achyranthes aspera|Achyranthes asper L. 土牛膝 土牛膝 云南民族药物志:第二卷 To quicken blood and dissipate stasis, dispel damp and disinhibit urine, clear heat and resolve toxin./Amenorrhea, dysmenorrhea, menstrual disorder, knocks and falls, pain in joints due to rheumatalgia, strangury, edema, fever due to external contraction, malaria, dysentery, sore pharynx, swollen welling abscess and clove sores. 白族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/苗族/彝族
TCMBANKHE007278/YEM-240 Achyranthes aspera var. indica|Achyranthes asper L. 钝叶土牛膝|土牛膝 土牛膝 云南民族药物志:第二卷 See Achyranthes aspera./See Achyranthes aspera . 白族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/苗族/彝族
TCMBANKHE008167/YEM-39/XU-672 Cortex Eucommiae|Eucommia ulmoides Oliv.|Eucommia ulmoides 杜仲 杜仲 云南民族药物志:第一卷|贵州省岑巩县平庄镇师兆村 To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE004643/YEM-590/XU-716 Folium Mori|Morus alba L.|Morus alba 桑叶|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE007773/YEM-590/XU-716 Ramulus Mori|Morus alba L.|Morus alba 桑枝|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To relieve rheumatic arthralgia./Hypertension, aching pain in joints, numbness in joints. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE004820/YEM-982 Diploclisia glaucescens|Diploclisia glaucescens(Bl.)Diels 苍白秤钩风 苍白秤钩风 云南民族药物志:第五卷 To dispel wind and eliminate damp, clear heat and resolve toxin./Wind-damp bone pain, swelling pain in throat, cholecystitis, dysentery, urinary tract infection, poisonous snake bite. 傣族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000298 SOD1 ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer superoxide dismutase 1