Compound Summary

  Compound Information

TCMBANKIN037382

化合物待补充

药名:	Aloeemodin
别名:	AC1Q6JR7; SMP2_000291; Aloe-emodol; 1,8-Dihydroxy-3-(hydroxymethyl)anthra-9,10-quinone; DSSTox_RID_78855; AS-11638; NCGC00163510-02; HY-N0189; CCG-208456; Diacerein impurity B, European Pharmacopoeia (EP) Reference Standard; AJ-48016; DTXSID2030695; BC216172; TL8003252; 3-(Hydroxymethyl)chrysazin; MLS000697563; BBL027838; 1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione; AK160272; 481-72-1; aloe emodine; MCULE-6965338444; RP29614; 1, 8-dihydroxy-3-hydroxymethylanthraquinone; BB_NC-2562; NCGC00255349-01; C10294; SR-01000765772; BG00617009; 9, 1,8-dihydroxy-3-(hydroxymethyl)-; ST24045939; DSSTox_CID_10695; Tox21_302400; NCGC00163510-03; Anthraquinone,8-dihydroxy-3-(hydroxymethyl)-; 1,8-Dihydroxy-3-(hydroxymethyl)anthra-9,10-quinone #; 1,8-Dihydroxy-3-hydroxymethyl-9,10-anthracenedione, 9CI; Aloeemodin; s2259; CS-3709; TR-031339; 1,8-Dihydroxy-3-hydroxymethylanthraquinone; 4-08-00-03578 (Beilstein Handbook Reference); AIDS-048396; InChI=1/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H; 1,8-dihydroxy-3-(hydroxymethyl)-9,10-anthrachinon; CAS-481-72-1; EINECS 207-571-7; UNII-C8IYT9CR7C; LMPK13040002; AC-020; NSC-38628; 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-hydroxymethyl-anthracene; 1,8-dihydroxy-3-methylol-9,10-anthraquinone; CCRIS 3526; AC1L1UPK; BG01563188; LS-2202; 1,8-dihydroxy-3-hydroxymethyl-anthraquinone; Aloe emodin; AX8006287; SR-01000765772-3; Q-100526; SC-46578; 3-Hydroxymethylchrysazin; Rhabarberone; AIDS048396; NSC 38628; BRN 2059062; C8IYT9CR7C; N1851; 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione; AB0010470; Aloe-emodin, >=95% (HPLC); ZINC4098644; aloe emodin; HMS3655N16; D09BUG; CHEMBL40275; 1,8-Dihydroxy-3-(hydroxymethyl)-anthracene-9,10-dione (Aloe-Emodin); NCGC00163510-01; MLS006011799; 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone; AN-16215; NCI60_003685; Aloeemodin:9,10-Anthracenedione,1,8-dihydroxy-3-(hydroxymethyl)-,; cid_10207; 3-Hydroxymethylchrysazine; Aloe-emodin; SMR000470920; aloeemod-in; MFCD00017373; LMPK02000031; STL146380; 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-; MolPort-003-931-716; FT-0622062; aloe-emodin; API0001418; 1,8-dihydroxy-3-(hydroxymethyl)anthra-9,10-quinone; Rottlerin?; ANTHRAQUINONE, 1,8-DIHYDROXY-3-HYDROXYMETHYL-; A7687_SIGMA; I14-1413; 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)- (9CI); CA-417; BDBM50085551; Aloe-emodine; YDQWDHRMZQUTBA-UHFFFAOYSA-N; NSC38628; Aloe-emodin, analytical standard; AKOS005720864; aloe-emodin ; SCHEMBL309756; 481A721; EMODINE; Anthraquinone, 1,8-dihydroxy-3-(hydroxymethyl)-; CHEBI:2607; DSSTox_GSID_30695; CA0128
成分:	HBIN015286
OB_score:	20.646669
CAS_id:	481-72-1
SymMap_id:	SMIT00148;SMIT00048
TCMID_id:	32406;967;23304;35638
TCMSP_id:	MOL002298;MOL000471
PubChem_id:	10207

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004340		萱草根			Edema, jaundice, strangury-turbidity, vaginal discharge, spontaneous external bleeding, hematochezia, flooding and spotting, scrofula, mammary welling abscess, galactostasis.
TCMBANKHE001170		猕猴桃根
TCMBANKHE004552	Rumex dentatus	牛舌草			To clear heat and resolve toxin, kill worms and relieve itch./Red swollen breast.
TCMBANKHE001849		倒扣草
TCMBANKHE003373	Exocarpium Citri grandis	化橘红			To dispel cold, eliminate damp and phlegm, and arrest emesis or nausea./Treatment of cough, itching of the throat and profuse expectoration in colds, nausea, vomiting and epigastric distension caused by improper diet or excessive drinking.
TCMBANKHE003426	Fructus Leonuri	茺蔚子			To activate blood circulation and regulate menstruation, to subdue hyperactivity of the liver, and to clear the eye of opacity./Treatment of menstrual disorders, amenorrhea, hysmenorrhea, inflammation of the eye with formation of corneal opacity, dizziness and headache.
TCMBANKHE003723	Flos Lonicerae	金银花			To remove toxic heat and dispel wind-heat./Infection of upper respiratory tract, tonsillitis, acute laryngitis, skin suppurations, welling abscess, viral conjunctivitis, influenza, pneumonia, mastitis, acute appendicitis, warm disease fever, heat toxin blood dysentery, swollen welling abscess and clove sores, throat impediment.
TCMBANKHE003734	radix tripterygii wilfordii	雷公藤			To expel wind-dampness, relieve swelling, alleviate pain and dredge the meridian passage./Rheumatoid arthritis, rheumatic arthritis, glomerulonephritis, nephropathy syndrome, erythematous lupus, dryness in eyes and mouth, Behcet’s syndrome, psoriasis, eczema, leprosy, scab sore, intractable lichen.
TCMBANKHE003738	Aloe	芦荟			1. To purge feces; 2. To clear heat in the liver; 3. To kill worms/Constipation, child gan accumulation, ascariasis, fright wind, lichen.
TCMBANKHE003752	Radix Salviae liguliobae	丹参			To remove blood stasis and relieve pain, to promote the flow of blood and stimulate menstrual discharge, and to ease the mind./Angina pectoris, cerebral atherosclerosis, diffusive intravascular clotting, thrombophlebitis, hepatitis, acute surgical infection, mastitis, erysipelas, otitis media, tonsillitis, bone marrow infection, menstrual disorder, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, pain in heart and abdomen, concretion conglomeration accumulation and gathering, heat impediment swelling and pain, knocks and falls, heat entering construction-blood, vexation and agitation, insomnia and vexation, swelling toxin of welling abscess and sore, zoster, neurodermatitis, psoriasis.
TCMBANKHE003822	Rumex patientia	牛西西			To clear heat and resolve toxin, stanch bleeding and disperse swelling, free stool and kill worms./Blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, red and white vaginal discharge, purpura, dysentery, hepatitis, constipation, inhibited urination, swelling toxin of welling abscess and sore, scab and lichen, knocks and falls, burns and scalds.
TCMBANKHE003911	Folium Sene	番泻叶			To purge feces downward/Heat bind and accumulation, constipation w ith abdominal pain, edema distention fullness.
TCMBANKHE004160	Semen Cassiae;Semen Sene	决明子			To remove heat from the liver, to improve eyesight, and to relax bowels./See Cassia obtusifolia.
TCMBANKHE004347	Rheum emodi [Syn. Rheum australe]	藏边大黄			To clear heat and resolve toxin, stanch bleeding and engender flesh./Lung heat cough, swelling pain in throat, swelling toxin of welling abscess and sore, bleeding due to external injury, hematochezia.
TCMBANKHE004404	Lignum Aquilariae Resitum	沉香			To promote the flow of qi and relieve pain, to arrest vomiting by warming the stomach, and to relieve asthma./Cold pain in stomach duct and abdomen, qi counterflow with asthma, stomach cold with retching counterflow, vacuity cold in lumbus and knees, vacuity constipation, qi strangury.
TCMBANKHE006313	Radix et Rhizoma Rhei	大黄			To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.
TCMBANKHE005748	Rheum tanguticum	唐古特大黄			See Rheum officinale./See Rheum officinale.
TCMBANKHE006028	Rhamnus davurica	鼠李			To clear heat and resolve toxin, drain precipitation and kill worms, relieve cough and dispel phlegm./Sore and welling abscess, scrofula, scab and lichen, decayed toothache, mout h sore, abdominal distention and constipation, cough of phlegm asthma, edema distention fullness.
TCMBANKHE008555	Polygonum multiflorum	何首乌			To lower cholesterol, enrich yin and nourish blood, moisten intestines and free stool, interrupt malaria, dispel wind, resolve toxin./Backache, neurasthenia, hyperlipemia, neurosis, insomnia, dizziness due to anemia, palpitation, limp aching lumbus and knees due to liver kidney yin vacuity, premature graying in beard and hair, tinnitus, emission, intestinal dry and constipation, enduring malaria, wind papule itching, sore and welling abscess, scrofula, hemorrhoids.
TCMBANKHE007253	Rubus alceaefolius	粗叶悬钩子			To clear heat and disinhibit damp, stanch bleeding, dispel stasis./Hepatitis, dysentery, enteritis, mastitis, stomatitis, march hematoglobinuria, bleeding due to external injury, liver spleen enlargement, knocks and falls, wind-damp bone pain.
TCMBANKHE008745	Cassia acutifolia	尖叶番泻叶			See Cassia angustifolia ./See Cassia angustifolia .
TCMBANKHE006968	Aloe ferox	好望角芦荟			See Aloe vera ./See Aloe vera .
TCMBANKHE008359	Semen Oroxyli	木蝴蝶			To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE008163	Oplopanax elatus	东北刺人参			To supplement qi and reinforce yang , suppress cough, free network vessels, abate fever./Qi vacuity and general weakness, fatigued spirit and lassitude, impotence, vacuity cough, wind-cold-damp impediment, diabetes mellitus, hypertension.
TCMBANKHE009105	Cassia mimosoides	山扁豆子			To clear heat and resolve toxin, fortify spleen and disinhibit damp, free stool./Jaundice, summerheat-heat and vomiting diarrhea, child gan accumulation, edema, inhibited urination, habitual constipation, poisonous snake bite.
TCMBANKHE007847	Caulis Millettiae; Caulis spatholobi	鸡血藤			To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE005980/YEM-13	herba Menthae;Mentha haplocalyx Briq|Mentha haplocalyx Briq.	薄荷	薄荷	云南民族药物志：第一卷	To dispel wind-heat from the head and eyes, and to promote eruption./Chronic urticaria, infection of upper respiratory tract, sarcoma, wind-heat exterior syndrome, headache and red eyes, swelling pain in throat, non-eruption of measles, dormant papules with pruritus, liver depression and rib-side pain, abdominal distention.	阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE004281/YNS-135/YEM-14	Cassia obtusifolia|Cassia tora Linn.|Cassia tora L.	钝叶决明|决明	决明根|草决明	云南药材标准：第三册|云南民族药物志：第一卷	安神补脑，清肝明目，理气止痛。主治失眠多梦，入睡易惊，腹内痉挛剧痛，腹部包块，黄疸，疟疾。|To clear liver and brighten eyes, disinhibit water and free stool./Red eyes with gall, delacrimation and photophobia, clear-eye blindness, night blindness, dizziness and headache, dim vision, cirrhosis with ascites, inhibited urination, habitual constipation, toxin swelling, skin lichen.	傣族/基诺族/拉祜族/傈僳族/苗族/佤族/彝族/藏族
TCMBANKHE006959/YNS-135/YEM-14	Semen Cassiae;Semen Sene|Cassia tora Linn.|Cassia tora L.	决明子;草决明|决明	决明根|草决明	云南药材标准：第三册|云南民族药物志：第一卷	安神补脑，清肝明目，理气止痛。主治失眠多梦，入睡易惊，腹内痉挛剧痛，腹部包块，黄疸，疟疾。|To remove heat from the liver, to improve eyesight, and to relax bowels.Treatment of inflammation in the eye with pain, photophobia and lacrimination, headache, dizziness, blurred vision and constipation./See Cassia obtusifolia.1. Oral adminstration of the hearbal powder can inhibit the rising of serum cholesterol and formation of atherosclerosis in rabbits.2. Its tincture and infusion can inhibit the myocardium of toad in vitro, and contract th eblood vessels of lower limbs.3. Its infusion can lower the blood pressure in dogs, cats and rabbits.4. Chrysophanol, one of the active components, is a laxative.5. Bacteriostatic.	傣族/基诺族/拉祜族/傈僳族/苗族/佤族/彝族/藏族
TCMBANKHE005036/YEM-158	Cassia occidentalis|Cassia occidentalis L.	望江南子|望江南	望江南	云南民族药物志：第一卷	To clear liver, fortify stomach, free stool, resolve toxin./Red eyes with gall, dizzy and distended head, indigestion, stomachache, dysentery, constipation, swollen welling abscess and toxin of clove.	阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE005278/YEM-158	Cassia occidentalis|Cassia occidentalis L.	望江南	望江南	云南民族药物志：第一卷	To clear lung, clear liver, calm asthma, disinhibit urine, free stool, resolve toxin and disperse swelling, lower blood pressure./Cough and asthma, hypertension, headache and red eyes, dribbling urination, constipation, swelling toxin of welling abscess and sore, snake or insect bites.	阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE005199/YEM-416/XU-321	Fructus Xanthii sibirici|Xanthium sibiricum Patrin ex Widder|Xanthium sibiricum	苍耳子|苍耳	苍耳子	云南民族药物志：第二卷|贵州省毕节市赫章县	To dispel wind and damp, and to relieve nasal obstruction./1. Lowering blood sugar, with similar mechanism as phenethyl biguanide ( DBI ). 2. Its chief poisonous component is rhamnose. The toxic effects in rats, guinea-pigs and rabbits by different routes of administration are similar. LD50 is 0.93g/kg in mice.	阿昌族/白族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE005460/YEM-471/XU-441	Tectona grandis|Tectona grandis L.f.	柚木	柚木	云南民族药物志：第三卷|云南省德宏州盈江县那邦镇铜壁关自然保护区	To harmonize center and check vomiting, dispel wind and relieve itch./Nausea and vomiting, wind papule itching.	傣族
TCMBANKHE007629/YEM-545	Aloe vera var. chinensis|Aloe vera (L.)Burm.f.var.chinensis(Haw.)Berg.	斑纹芦荟|芦荟	斑纹芦荟	云南民族药物志：第三卷	See Aloe vera ./See Aloe vera .	傣族/德昂族/哈尼族/瑶族/壮族
TCMBANKHE004455/YEM-744/XU-850	Rheum palmatum|Rheum palmatum L.	掌叶大黄	掌叶大黄	云南民族药物志：第四卷|西藏昌都地区芒康县	See Rheum officinale./See Rheum officinale.	阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族
TCMBANKHE007363/YEM-744/XU-850	Radix et Rhizoma Rhei|Rheum palmatum L.|Rheum palmatum	大黄; 生锦纹; 生军|掌叶大黄	掌叶大黄	云南民族药物志：第四卷|西藏昌都地区芒康县	To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge.; Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.; 1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect.	阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000138	PRKCE	PKCE; nPKC-epsilon	protein kinase C epsilon
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000256	PRKCA	AAG6; PKC-alpha; PKCA; PKCI+/-; PKCalpha; PRKACA	protein kinase C alpha
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000294	CDKN1A	CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1	cyclin dependent kinase inhibitor 1A
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000859	PRKCD	ALPS3; CVID9; MAY1; PKCD; nPKC-delta	protein kinase C delta
TCMBANKGE000898	MYC	MRTL; MYCC; bHLHe39; c-Myc	MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000921	CCNB1	CCNB	cyclin B1
TCMBANKGE000923	CDK1	CDC2; CDC28A; P34CDC2	cyclin dependent kinase 1
TCMBANKGE000925	PCNA	ATLD2	proliferating cell nuclear antigen
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000970	FASN	FAS; OA-519; SDR27X1	fatty acid synthase
TCMBANKGE000994	AKR1B1	ADR; ALDR1; ALR2; AR	aldo-keto reductase family 1 member B
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001177	TP53	BCC7; BMFS5; LFS1; P53; TRP53	tumor protein p53
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE003210	POLD1	CDC2; CRCS10; MDPL; POLD	DNA polymerase delta 1, catalytic subunit
TCMBANKGE003300	EIF6	CAB; EIF3A; ITGB4BP; b(2)gcn; eIF-6; p27(BBP); p27BBP	eukaryotic translation initiation factor 6
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE007924	PKIA	PRKACN1	cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1