Compound Summary


  Compound Information

药名:

Lutein

别名:

SMP1_000317; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-2-en-1-ol; SCHEMBL10029505; CHEBI:28838; NSC59193; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-1-cyclohex-2-enol; C08601; LMPR01070274; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyl-octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-2-en-1-ol; (1R,4R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyl-octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-2-en-1-ol; lutein; 127-40-2; Xanthophyll; (3R,3'R,6'R)-beta,epsilon-carotene-3,3'-diol; BCBcMAP01_000190; (1R,4R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-2-en-1-ol; (1R,4R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-1-cyclohex-2-enol

分子式:

C40H56O2

Smiles:

CC1=C(C(CC(C1)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2C(=CC(CC2(C)C)O)C)C)C

成分:

HBIN033793

OB_score:

22.586555

CAS_id:

127-40-2

SymMap_id:

SMIT14030;SMIT16369

TCMID_id:

13119

TCMSP_id:

MOL013377

PubChem_id:

5281243


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001520 Rapanea umbellata 三华密花树
TCMBANKHE004633 Setaria italica 粟米 To harmonize center, boost kidney, eliminate heat, resolve toxin./Spleen-stomach vacuity heat, stomach reflux vomiting, reduced food intake with abdominal distention, diabetes mellitus, diarrhea, scalds.
TCMBANKHE002188 Penaeus orientalis To supplement kidney and invigorate yang , open stomach and transform phlegm./Kidney vacuity impotence, convulsion of hands and feet, wind stroke with hemiplegia, mammary sore, enduring sores.
TCMBANKHE002730 橘络
TCMBANKHE002762 Radix et Rhizoma Thalictri 马尾莲 Influenza, fever in children, common cold with fever, measles papules, malaria, damp-heat diarrhea dysentery, jaundice, red eyes with gall.
TCMBANKHE003719 Flos Chrysanthemi 杭菊 Treatment of wind-heat type common cold, headache and dizziness, inflammation of the eye, blurred vision./Treatment of wind-heat type common cold, headache and dizziness, inflammation of the eye, blurred vision.
TCMBANKHE003843 Citrus limon 柠檬 To engender liquid and allay thirst, dispel summerheat, quiet fetus./Stomach heat fluid damage, summerheat stroke with vexation and thirst, inappetence, glomus distention in stomach duct and abdomen, lung heat dry cough, vomiting in pregnancy.
TCMBANKHE004014 Helicteres isora 火索麻 To move qi and relieve pain./Chronic gastritis, gastric ulcer, ileus, enteritis and diarrhea.
TCMBANKHE004097 Citrus limonia 黎檬叶 See Citrus limon./See Citrus limon.
TCMBANKHE004107 Carassius auratus 金鱼 To clear heat, disinhibit water, resolve toxin./Cough, jaundice, ascites ulcer.
TCMBANKHE007750 Gallus gallus domesticus 鸡子白 To moisten lung and disinhibit throat, clear heat and resolve toxin./Deep-lying heat sore pharynx, aphonia, red eyes, vexation and fullness, cough and counterflow, dysentery, jaundice, swelling toxin of sore and welling abscess, burns and scalds.
TCMBANKHE004651 Medulla Junci 灯心草 To eliminate excess fire in the heart, and to induce diuresis./Strangury, edema, inhibited urination, damp-heat jaundice, insomnia and vexation, infant night crying, throat impediment, mouth sore, wound.
TCMBANKHE006655 Cyprinus carpio 鲤鱼皮 To quiet fetus, stanch bleeding./Stirring fetus in pregnancy, fetal spotting, bone stuck in throat.
TCMBANKHE004773 Herba Pteridis multifidae 凤尾草 1. To clear heat and toxic material. 2. To cool the blood and stop bleeding./Dysentery, diarrhea, strangury-turbidity, vaginal discharge, jaundice, swelling toxin of clove sore, throat impediment with nipple moth, scrofula, parotitis, mastitis, ardent fever and convulsion, snake or insect bites, blood ejection, spontaneous external bleeding, hematuria, hematochezia, bleeding due to external injury.
TCMBANKHE004791 Herba Spirodelae 浮萍 To dispel wind-heat, to promote eruption, and to cause diuresis./Wind-heat exterior syndrome, non-eruption of measles, dormant papules with pruritus, edema, dribbling urinary block, sore and lichen, erysipelas, scalds.
TCMBANKHE004864 Porphyra tenera 紫菜 To transform phlegm and soften hardness, clear heat and disinhibit urine./Goiter and tuberculosis, beriberi, edema, strangury, swelling pain in throat, cough, diarrhea.
TCMBANKHE004910 Cuscuta australis 南方菟丝子 See Cuscuta chinensis ./See Cuscuta chinensis .
TCMBANKHE004912 Flos Caryophylli 丁香 To warm the spleen and stomach, to regulate the adverse flow of the stomach qi, and to restore the kidney yang./Stomach cold with retching counterflow, hiccough, cold pain in stomach duct and abdomen, reduced food intake and diarrhea, kidney vacuity impotence, vacuity cold in lumbus and knees, yin flat abscess.
TCMBANKHE005221 Semen Ginkgo 白果 1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE005252 枳椇子 Drunkenness, vexation and thirst, vomiting, inhibited urine and stool.
TCMBANKHE007942 Vaccinium macrocarpon 美洲酸果萝
TCMBANKHE005315 Potamogeton perfoliatus 酸水草 To dispel wind and disinhibit damp./Eczema, itchy skin.
TCMBANKHE007467 Amentotaxus yunnanensis 云南穗花杉
TCMBANKHE008354 Semen Ginkgo 白果 1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE008626 Cortex Lycii Radicis 地骨皮 To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung./1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect.
TCMBANKHE006802 Duranta repens 假连翘叶 To dissipate stasis and resolve toxin./Stasis swelling from knocks and falls, swollen welling abscess.
TCMBANKHE006940 Herba Potentillae Discoloris 翻白草 1. To clear away heat and toxic material. 2. To cool the blood and stop bleeding./Cough and asthma due to lung heat, diarrhea dysentery, malaria, hacking of blood, blood ejection, bloody stool, flooding and spotting [=metrorrhagia and metrostaxis], swelling toxin of welling abscess and sore, scrofula.
TCMBANKHE007098 Fructus Gardeniae 栀子;生山栀 1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness;4.Treatment of febrile diseases with restlessness, jaundice with dark urine, hematuria with difficult painful urination, hemoptysis and epistaxis caused by heat in the blood, inflammation of the eye, boils and sores, external use for sprains and bruises.Fructus Gardeniae (charred): Hemoptysis, epistaxis, hematuria and abnormal uterine bleeding caused by heat in the blood./Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria.1. The active components such as crocin, crocetin, genipin, or alcoholic extract protect the liver from carbon tetrachloride and increasing biliary secretion. Oral use of its decoction induce gallbladder contraction.2. Oral or intraperitoneal use of its decoction and alcoholic extract exerts a sustained hypotensive effect in anaesthetized and un-anaesthetized animals.3. Hemostatic.
TCMBANKHE007351 Gallus gallus domesticus 鸡子黄 To enrich yin and moisten dryness, nourish blood and extinguish wind./Insomnia and vexation, febrile diseases tetanic reversal, vacuity taxation blood ejection, retching counterflow, dysentery, scalds, heat sore, hepatitis, child indigestion.
TCMBANKHE007933 Citrus limonia 黎檬 See Citrus limon./See Citrus limon .
TCMBANKHE004944/XU-432 Taraxacum officinale 药用蒲公英 湖北省恩施州板桥镇
TCMBANKHE004506/YEM-137 Radix Notoginseng|Panax notoginseng (Burk.) F, H. Chen ex C.Chow et al. 三七 三七 云南民族药物志:第一卷 To eliminate blood stasis, arrest bleeding, cause subsidence of swelling and alleviate pain./Hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, angina pectoris, stabbing pain in chest and abdomen, painful swelling from knocks and falls. 彝族
TCMBANKHE008379/YEM-210 Tagetes erecta|Tagetes erecta L. 万寿菊 万寿菊 云南民族药物志:第二卷 To clear heat and resolve toxin, relieve cough and transform phlegm./Infection of upper respiratory tract, pertussis, conjunctivitis, stomatitis, toothache, dizziness, infant fright wind, amenorrhea, blood stasis and abdominal pain, swelling toxin of welling abscess and sore. 傣族
TCMBANKHE005651/YEM-290/YEM-296 Oryza sativa|Oryza sativa L.var. glutinosa Matsum. 稻草|糯稻 糯稻 云南民族药物志:第二卷 To loosen center, precipitate qi, disperse food, resolve toxin./Dysphagia-occlusion, stomach reflux, food stagnation, abdominal pain, diarrhea, diabetes mellitus, jaundice, throat impediment, hemorrhoids, scalds. 白族/傣族/哈尼族/彝族
TCMBANKHE006507/YEM-290/YEM-296 Oryza sativa|Oryza sativa L.var. glutinosa Matsum. 粳米|糯稻 糯稻 云南民族药物志:第二卷 To supplement qi and fortify spleen, eliminate vexation and allay thirst, check dysentery and diarrhea ./Spleen-stomach vacuity, reduced food intake, fatigue hypodynamia, vexation and thirst, diarrhea. 白族/傣族/哈尼族/彝族
TCMBANKHE009032/YEM-44/XU-443 Psidium guajava|Psidium guajava L. 番石榴皮;芭乐皮|番石榴 番石榴 云南民族药物志:第一卷|广东湛江市 To promote astriction, check diarrhea, close sores./Damp toxin of scab sore, toothache, sore and boil in children. 傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族
TCMBANKHE005889/YEM-44/XU-443 Psidium guajava|Psidium guajava L. 番石榴皮|番石榴 番石榴 云南民族药物志:第一卷|广东湛江市 To promote astriction, check diarrhea, close sores./Damp toxin of scab sore, toothache, sore and boil in children. 傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族
TCMBANKHE005522/YEM-745/XU-411 Fructus Gardeniae|Gardenia jasminoides(L.)Ellis|Gardenia jasminoides 栀子 栀子 云南民族药物志:第四卷|广东省廉江市石岭镇 1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness/Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria. 阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/水族/瑶族/彝族/壮族
TCMBANKHE008693/YEM-843 Ananas comosus|Ananas comosus(L.)Merr. 凤梨|菠萝 菠萝 云南民族药物志:第五卷 To resolve toxin, check dysentery, relieve cough./Dysentery, cough. 傣族/佤族
TCMBANKHE007016/YEM-883/XU-811 Cuscuta japonica|Cuscuta japonica Choisy 大菟丝子|金灯藤 金灯藤 云南民族药物志:第五卷|云南省曲靖市会泽县 See Cuscuta chinensis./See Cuscuta chinensis . 傣族/苗族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000282 ELN ADCL1; SVAS; WBS; WS elastin
TCMBANKGE000624 ALPL AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP alkaline phosphatase, biomineralization associated
TCMBANKGE000934 GFAP ALXDRD glial fibrillary acidic protein
TCMBANKGE001045 CCND1 BCL1; D11S287E; PRAD1; U21B31 cyclin D1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001080 AHR RP85; bHLHe76 aryl hydrocarbon receptor
TCMBANKGE001132 BAX BCL2L4 BCL2 associated X, apoptosis regulator
TCMBANKGE001141 PPARA NR1C1; PPAR; PPARalpha; hPPAR peroxisome proliferator activated receptor alpha
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001177 TP53 BCC7; BMFS5; LFS1; P53; TRP53 tumor protein p53
TCMBANKGE001178 STAT3 ADMIO; ADMIO1; APRF; HIES signal transducer and activator of transcription 3
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE001697 MMP1 CLG; CLGN matrix metallopeptidase 1
TCMBANKGE001901 BCO1 BCDO; BCDO1; BCMO; BCMO1; BCO beta-carotene oxygenase 1
TCMBANKGE003578 RARA NR1B1; RAR retinoic acid receptor alpha