Compound Summary


  Compound Information

药名:

formononetin

别名:

Oprea1_815287; AIDS027672; 7-hydroxy-3-(4-methoxyphenyl)-4H-benzopyran-4-one; Isoflavone, 7-hydroxy-4'-methoxy- (8CI); NCI60_042081; NCGC00095207-03; Oprea1_139748; NCIOpen2_005983; SDCCGMLS-0066428.P001; CHEBI:18088; TNP00176; 485-72-3; Formononetol; Isoflavone, 7-hydroxy-4'-methoxy-; 7-hydroxy-3-(4-methoxyphenyl)chromone; Spectrum2_000560; Formononetin; NSC 93360; EINECS 207-623-9; 47752_FLUKA; KBio2_000853; 7-Hydroxy-3-(4-methoxyphenyl)-4-benzopyrone; Spectrum5_000258; KBio3_001519; NSC93360; KBioSS_000853; Spectrum_000373; SPECTRUM102007; KBio2_005989; Biochanin B; KBioGR_001878; NCGC00017269-01; 7-Hydroxy-3-(4′-methoxyphenyl)-4H-benzopyran-4-one; formononetin ; 7-hydroxy-4'-methoxy-isoflavone; BSPBio_002299; ZINC00113304; 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)- (9CI); SBB016445; Spectrum3_000660; 7-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one; Spectrum4_001429; DivK1c_006319; KBio2_003421; SPBio_000639; NCGC00095207-01; KBio1_001263; AIDS-027672; 7-Hydroxy-4'-methoxyisoflavone; C00858; 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)-; NCGC00095207-02; SpecPlus_000223

分子式:

C16H12O4

Smiles:

C1([H])=C(c2c([H])c([H])c(OC([H])([H])[H])c([H])c2[H])C(c3c(O1)c([H])c(O[H])c([H])c3[H])=O

成分:

HBIN026662

OB_score:

69.673881

CAS_id:

485-72-3

SymMap_id:

SMIT00037;SMIT02619

TCMID_id:

7882

TCMSP_id:

MOL000392;MOL010586

PubChem_id:

5280378


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000369 Euphorbia portlandica
TCMBANKHE000541 甘草头
TCMBANKHE000956 flos puerariae lobatae 葛花 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Treatment of fever, headache and stiffness of th nape in exogenous affections, thirst, diabetes, measles with inadequate eruption, acute dysentery or diarrhea, stiff and painful nape in hypertension.
TCMBANKHE000999 红芪 to promote the drainage of pus and the growth of new tissue.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001384 Radix Glycyrrhizae uralensis 甘草稍
TCMBANKHE001475 Virola multinervia 多买南美肉豆蔻
TCMBANKHE001608 Dalbergia ecastophyllum 易卡托叶黄檀
TCMBANKHE001634 Fructus Choerospondiatis 广枣 To promote the flow of qi and blood, to replenish the heart and allay excitement./Treatment of stagnation of qi and blood with pectoral pain, palpitation and shortness of breath, uneasiness in mind.
TCMBANKHE006338 Glycyrrhiza glabra 光果甘草 See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis .
TCMBANKHE002243 泡桐果
TCMBANKHE004897 Piptanthus nanus 小沙冬青 See Ammopiptanthus mongolicus./See Ammopiptanthus mongolicus.
TCMBANKHE003151 Dalbergia stevensonii
TCMBANKHE003216 Virola caducifolia 落花南美肉豆蔻
TCMBANKHE003349 甘草节
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE003743 Radix Astragali 黄芪 To reinoforce qi and invigorate the function of the spleen./Common cold, influenza, chronic wound ulcer, chronic glomerulonephritis, diabetes mellitus due to internal heat, qi vacuity edema, chronic gastritis, qi vacuity and hypodynamia, reduced food intake and sloppy stool, center qi fall, chronic diarrhea, prolapse of rectum, hematochezia, flooding and spotting, spontaneous sweating due to exterior vacuity.
TCMBANKHE003744 Rhizoma Atractylodis macrocephalae 白术 To invigorate the function of the spleen and replenish qi, to eliminate damp by causing diuresis, to arrest excesssive perspiration, and to prevent miscarriage./Spleen qi vacuity, fatigue hypodynamia, reduced food intake with abdominal distention, sloppy stool, water-rheum collecting internally, inhibited urination, edema, phlegm-rheum dizziness, damp impediment, qi vacuity, spontaneous sweating, stirring fetus in pregnancy.
TCMBANKHE003749 Radix Puerariae 葛根 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Angina pectoris, hypertension, headache due to externally contracted wind-heat, rigidity of neck, thirst, diabetes mellitus, non-eruption of measles, heat dysentery, diarrhea, deafness in early stage, optic nerve atrophy, retinitis.
TCMBANKHE003919 Medicago sativa 苜蓿 To clear heat and cool blood, disinhibit damp and abate jaundice./Febrile diseases with vexation and fullness, jaundice, enteritis, dysentery, edema, urethral stone, hematochezia from hemorrhoids.
TCMBANKHE007615 Rhizoma Sparganii 三棱 To eliminate blood stasis with strong effect, promote the flow of qi, remove the retention of undigested food, and relieve pain./Concretion conglomeration accumulation and gathering, qi-blood stagnation, pain in heart and abdomen, distending pain in rib-side, amenorrhea, postpartum blood stasis abdominal pain, knocks and falls, swelling of sores.
TCMBANKHE003970 Typha latifolia 宽叶香蒲 See Typha angustata ./See Typha angustata .
TCMBANKHE005771 Ononis spinosa 刺芒柄花
TCMBANKHE005773 Herba Lycopodii 伸筋草 To relieve rheumatic conditions and muscular contracture./Wind-cold-damp impediment, aching pain in joints, arthritis, dysmenorrhea, skin numbness, weakness in limbs, jaundice, cough, knocks and falls, sores, zoster, scalds.
TCMBANKHE004121 Radix Stemoe 百部 1. To moisten the lungs and stop cough; 2. To kill lice and parasites/Wind-cold cough, pertussis, tuberculosis, senile cough and asthma, ascariasis, oxyuria disease, scab and lichen, eczema, cootie.
TCMBANKHE006055 Herba Potentillae Chinensis 委陵菜 To remove toxic heat and reduce heat in blood, and to relieve dysentery./Red dysentery and abdominal pain, enduring dysentery, bleeding hemorrhoids, swelling toxin of sore and welling abscess.
TCMBANKHE004366 Cicer arietinum 回回豆 To clear heat and resolve toxin./Diabetes mellitus.
TCMBANKHE004374 Urtica cannabina 荨麻 To dispel wind and free network vessels, calm liver and settle fright, disperse accumulation and free stool, resolve toxin./Wind-damp impediment pain, postpartum wind tetany, infant fright wind, sequel of poliomyelitis, hypertension, indigestion, fecal stoppage, urticaria, knocks and falls, snake or insect bites.
TCMBANKHE006199 Trifolium subterraneum 地下车轴草
TCMBANKHE006212 Semen Astragali Complanati;Semen Astragali Complati 潼蒺藜;沙苑子 Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision,to benefit the liver./Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision.
TCMBANKHE008354 Semen Ginkgo 白果 1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE004613 flos Sophorae 槐花 To arrest bleeding by reducing heat in blood, and to quench excess fire in the liver./1. Its component rutin decreases capillay permeability. 2. Lowering blood pressure transiently in anesthetized dog. 3. Inhibiting the growth of various dermatomyces.
TCMBANKHE006505 Semen Lablab Album 白扁豆 To invigorate the spleen and remove damp, paticularly the summer damp.Semen Lablab Album (stir-fried) To invigorate the spleen and remove damp./Treatment of weakness of the spleen and stomach with loss of appetite and loose bowels, excessive leukorrhea, vomiting, diarrhea, distress in the chest and distension in the abdomen caused by summer-damp.Semen Lablab Album (stir-fried) Diarrhea and excess
TCMBANKHE004763 Glycyrrhiza pallidiflora 刺果甘草 To promote lactation./Postpartum scant milk.
TCMBANKHE004838 Radix Sophorae Tonkinensis 山豆根 To remove toxic heat, promote the subsidence of swelling, and soothe the sore throat./Septicemia, ulcer of uterine cervix, chronic cervicitis, bacillary dysentery, enteritis, hydatid moles, chorioblastoma, asthma, chronic bronchitis, acute tonsillitis, laryngitis, accumulated fire toxin, swelling pain in throat, gingiva painful swelling.
TCMBANKHE004862 Lignum Dalbergiae odoriferae Rosewood 降香 To relieve pain by promoting the circulation of qi and blood, and to arrest bleeding./Shortening the plasma recalcification time in rabbits.
TCMBANKHE007070 Dalbergia cearensis 西阿拉黄檀
TCMBANKHE005218 Andira inermis 无刺柯桠树
TCMBANKHE005221 Semen Ginkgo 白果 1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE005292 Pterocarpus indicus 紫檀 To dispel stasis and harmonize construction, stanch bleeding and settle pain./Headache, pain in heart and abdomen, persistent flow of lochia, dribbling pain of urination, wind toxin and swollen welling abscess, incised wound and bleeding.
TCMBANKHE007546 Glycyrrhiza inflata 胀果甘草 See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis.
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE007926 Flemingia philippinensis [Syn. Moghania philippinensis];Moghania philippinensis 蔓性千斤拔;菲律宾千斤拔 To dispel wind and eliminate damp, strengthen sinews and bones, quicken blood and resolve toxin./Wind-damp impediment pain, taxation damage in lumbar muscle, wilting-weakness in limbs, knocks and falls, swelling pain in throat.
TCMBANKHE007985 Caragana chamlagu 锦鸡儿 To fortify spleen and boost kidney, harmonize blood and dispel wind, resolve toxin./Vacuity taxation cough, dizzy head and tinnitus, limp aching lumbus and knees, qi vacuity, vaginal discharge, child gan accumulation, pox without coming out, mammary welling abscess, pain wind, knocks and falls.
TCMBANKHE008040 Astragalus mongholicus 蒙古黄芪 See Astragalus membranaceus./See Astragalus membranaceus.
TCMBANKHE007847 Caulis Millettiae; Caulis spatholobi 鸡血藤 To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE005495/XU-730 Radix Euphorbiae Pekinensis|Euphorbia pekinensis 京大戟|大戟 陕西省安康市旬阳县 To cause drastic purgation./Treatment of anasarca, hydrothorax and ascites with dyspnea, constipation and oliguria.
TCMBANKHE007981 Trifolium pratense 红车轴草 To clear heat and relieve cough, dissipate binds and disperse swelling./Common cold, cough and asthma, hard swelling, burns.
TCMBANKHE008315 Cortex erythrie 海桐皮 1. To dispel wind and dampness; 2. To clear the meridians/Wind-damp impediment, pain in lumbus and knees, scab sore, lichen, eczema.
TCMBANKHE008538 土荆皮 Scab and lichen, eczema, neurodermatitis .
TCMBANKHE008503 Radix Sophorae flavescentis 苦参 To remove heat and damp, to kill parasites, and to cause diuresis./Arrhythmia, otitis media, acute conjunctivitis, chronic conjunctivitis, trichomoniasis, septicemia, edema, damp-heat diarrhea, intestinal wind bleeding, acute jaundice, inhibited urination, vaginal discharge, pudendal itch, scab and lichen, leprosy, itchy skin, eczema, damp toxin sore, suppurative nest sore.
TCMBANKHE008647 Apis mellifera ligustica 蜂胶 To eliminate inflammation and relieve pain, moisten skin and engender flesh./Gastric ulcer, oral ulcer, cervical erosion, zoster, psoriasis, skin chap and pain, clavus, wound, carcinoma.
TCMBANKHE007259/XU-659 Amorpha fruticosa 紫穗槐 安徽省亳州市蒙城县双涧镇 To clear heat and resolve toxin, dispel damp and disperse swelling./Welling abscess, burns and scalds, eczema.
TCMBANKHE006668/YEM-19 Aquilaria sinensis|Aquilaria sinensis (Lour.) Spreng. 白木香 沉香 云南民族药物志:第一卷 See Aquilaria agallocha./See Aquilaria agallocha . 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族
TCMBANKHE008622/YNS-103/YEM-312/XU-348 Arachis hypogaea|Arachis hypogaea Linn.|Arachis hypogaea L. 落花生 花生壳|落花生 云南药材标准:第七册|云南民族药物志:第二卷|云南省文山州广南县 健脾化痰、敛肺止咳。用于痰浊咳嗽。|To fortify spleen and nourish stomach, moisten lung and transform phlegm./Stomach reflux, scant breast milk, beriberi, lung heat dry cough, dry stool. 傣族/哈尼族/佤族
TCMBANKHE003926/YEM-709 Herba Lycopodii;Lycopodium japonium;Common Clubmoss Herb|Lycopodium japonicum Thunb.ex hwvzay 伸筋草|石松 石松 云南民族药物志:第四卷 To relieve rheumatic conditions and muscular contracture.;Treatment of arthralgia with limited mobility of the joints./Wind-cold-damp impediment, aching pain in joints, arthritis, dysmenorrhea, skin numbness, weakness in limbs, jaundice, cough, knocks and falls, sores, zoster, scalds.;Treatment of arthralgia with limited mobility of the joints. 布依族/傣族/基诺族/傈僳族/苗族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000313 JUN AP-1; AP1; c-Jun; cJUN; p39 Jun proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000315 IL4 BCGF-1; BCGF1; BSF-1; BSF1; IL-4 interleukin 4
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001182 SIRT1 SIR2; SIR2L1; SIR2alpha sirtuin 1
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE007504 HSD3B1 3BETAHSD; HSD3B; HSDB3; HSDB3A; SDR11E1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
TCMBANKGE007589 ATP5F1B ATP5B; ATPMB; ATPSB; HEL-S-271 ATP synthase F1 subunit beta
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE010924 HSD3B2 HSD3B; HSDB; SDR11E2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1