Compound Summary


  Compound Information

药名:

Isobrucine

别名:

isobrucine

分子式:

C23H28N2O4

Smiles:

c1(OC([H])([H])[H])c([H])c([C@@]2([C@@]([H])(N3C([H])([H])C2([H])[H])C([H])([H])[C@@]4([H])\C(=C([H])/C([H])([H])O[H])\C3([H])[H])[C@@]([H])([C@]4([H])C([H])([H])C([H])([H])C5=O)N56)c6c([H])c1OC([H])( [H])[H]

成分:

HBIN030507

OB_score:

33.579947

SymMap_id:

SMIT05504;SMIT15988

TCMID_id:

11262

TCMSP_id:

MOL003436;MOL003437

PubChem_id:

101532796


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE002292 橘红
TCMBANKHE003725 Rhizoma Zingiberis Recens 生姜 To induce perspiration and dispel cold, to warm the stomach and arret vomiting, and to resolve phlegm and relieve cough./Wind-cold common cold, fever and aversion to wind, headache and nasal congestion, vomiting, phlegm-rheum cough asthma, distention fullness, diarrhea.
TCMBANKHE003753 Borneolum syntheticum 冰片 1. To open the orifices and clear the mind; 2. To clear heat and stop pain/Angina pectoris, phlegm reversal, wind stroke, coma, convulsion, swelling pain in throat, mouth sore, swollen and painful eyes, sores, ulcer.
TCMBANKHE003857 Semen Strychni 马钱子 To promote the flow of qi and blood in the collaterals, relieve pain, and promote the subsidence of swelling./Hemiplegia, numbness and paralysis, muscle weakness, impotence, hypertrophic spinitis, chronic anemia, wind-damp intractable impediment, sequel of poliomyelitis, rheumatoid arthritis, knocks and falls, swelling pain of welling abscess and flat abscess.
TCMBANKHE006056 Rhizoma Menispermi 北豆根 To remove toxic heat and relieve rheumatic pains./Treatment of sore throat, colitis, dysentery, rheumatic arthralgia.
TCMBANKHE004431 Semen Strychni;Strychnos dolichothyrsa;Semen Cumini Cymni;Strychnos mittschelichii 马钱子 To promote the flow of qi and blood in the collaterals, relieve pain, and promote the subsidence of swelling./Hemiplegia, numbness and paralysis, muscle weakness, impotence, hypertrophic spinitis, chronic anemia, wind-damp intractable impediment, sequel of poliomyelitis, rheumatoid arthritis, knocks and falls, swelling pain of welling abscess and flat abscess.
TCMBANKHE004023/YEM-391/XU-797 Fructus Ligustri lucidi|Ligustrum lucidum Ait.|Ligustrum lucidum 女贞子|女贞 女贞子 云南民族药物志:第二卷|云南省文山州麻栗坡县 To replenish the liver and kidney, improve eyesight and promote the growth of black hair.;Treament of vertigo, tinnitus, weakness in the loins and knees, premature whitening of hair and impaired eyesight due to deficiency of yin of the liver and kidney./Septicemia, chronic bronchitis, acute dysentery, dizziness and tinnitus, premature graying in beard and hair, dim vision.;1. Its component oleanolic acid can prevent and relieve cyclophosphamide-induced leukocytopenia in mice.2. Enhancing the anoxia tolerance of mice under atmospheric pressure.3. Increasing coronary flow in rabbits in vitro.4. Relaxing adrenaline-induced vasocontricyion in rabbits in vitro.5. Lowering the level of blood lipid. 阿昌族/德昂族/基诺族/景颇族/傈僳族/水族
TCMBANKHE008476/YEM-68 Artemisia annua|Artemisia annua L. 黄花蒿 黄花蒿 云南民族药物志:第一卷 To clear heat, resolve summerheat, eliminate steam, interrupt malaria./Summerheat-heat, summerheat-damp, damp warmth, yin vacuity fever, malaria, jaundice. 阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003157 CHRM2 HM2 cholinergic receptor muscarinic 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008700 CHRNA2 - cholinergic receptor nicotinic alpha 2 subunit
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE011923 CHRM4 HM4; M4R cholinergic receptor muscarinic 4
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1