Compound Summary

  Compound Information

TCMBANKIN039229

药名:	Oxychelerythrine
别名:	28342-33-8; AKOS032948933; LS-52943; AC1L3UTW; 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-13-one; ZINC900932; DTXSID70182584; SCHEMBL10633372; Dihydrooxochelerythrine; 1,2-Dimethoxy-12-methyl-(1,3)benzodioxolo(5,6-c)phenanthridin-13(12H)-one; C12225; BRN 0345198; MolPort-039-338-210; CCRIS 3805; CHEBI:31141; 17,18-DIMETHOXY-21-METHYL-5,7-DIOXA-21-AZAPENTACYCLO[11.8.0.0(2),(1)?.0?,?.0(1)?,(1)?]HENICOSA-1,3,8,10,12,14(19),15,17-OCTAEN-20-ONE; (1,3)Benzodioxolo(5,6-c)phenanthridin-13(12H)-one, 1,2-dimethoxy-12-methyl- (9CI); oxychelerythrine; Oxycheleritrine; [1,3]Benzodioxolo[5,6-c]phenanthridin-13(12H)-one,1,2-dimethoxy-12-methyl-; Chelerythrine, 12,13-dihydro-13-oxo-; 6-Oxochelerythrine; 4-27-00-06655 (Beilstein Handbook Reference); 7,8-dimethoxy-2,3-methylenedioxy-5-methylbenzo [c]phenanthridin-6(5h)-one; (1,3)Benzodioxolo(5,6-c)phenanthridin-13(12H)-one, 1,2-dimethoxy-12-methyl-
分子式:	C21H17NO5
Smiles:	CN1C2=C(C=CC3=CC4=C(C=C32)OCO4)C5=C(C1=O)C(=C(C=C5)OC)OC
成分:	HBIN038476
OB_score:	44.216056
CAS_id:	28342-33-8
SymMap_id:	SMIT06909;SMIT17059
TCMID_id:	16432
TCMSP_id:	MOL005105
PubChem_id:	147279

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000810	Radix Zanthoxyli	两面针			To promote the flow of qi, relieve pain, to eliminate blood stasis, to promote blood circulation and dispel wind./Treatment of traumatic injury, rheumatic arthralgia, stomach-ache, teethache, bitten by venomous snake, applied for burn caused by hot liquid or fire.
TCMBANKHE004459	Fructus Lycii	枸杞子			To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE005000	Pericarpium Zanthoxyli	花椒			To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE007987	Zanthoxylum simulans	野花椒皮			To dispel wind and eliminate damp, dissipate cold and relieve pain, resolve toxin./Wind-cold-damp impediment, sinew and bone numbness, cold pain in stomach duct and abdomen, vomiting and diarrhea, toothache, skin sores, poisonous snake bites.
TCMBANKHE007829	Pericarpium Zanthoxyli	花椒			To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE003964/YEM-214/XU-446	Zanthoxylum nitidum|Zanthoxylum nitidum (Roxb.)DC	入地金牛|两面针	两面针	云南民族药物志：第二卷|广东省廉江市石岭镇	To dispel wind and free network vessels, disperse swelling and relieve pain./Wind-damp bone pain, stomachache, toothache, throat impediment, scrofula, burns and scalds.	傣族/哈尼族
TCMBANKHE005663/YNS-73/YEM-663	Toddalia asiatica|Toddalia asiatica (L.) Lam.|Toddalia asiatica(L.)Lam.	飞龙掌血	飞龙掌血茎|飞龙掌血	云南药材标准：第四册|云南民族药物志：第四卷	活血止痛，祛风散寒。用于胃脘疼痛；腰痛，寒湿痹痛，跌倒损伤；皮肤瘙痒|To dispel wind and relieve pain, stanch bleeding and dissipate stasis./Wind-damp Pain, stomachache, knocks and falls, blood ejection, spontaneous external bleeding, knife wound, amenorrhea, dysmenorrhea.	阿昌族/布依族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/佤族/瑶族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000121	KCNH2	ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1	potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1