Compound Summary


  Compound Information

药名:

Furanodiene

别名:

(5Z,9Z)-3,6,10-trimethyl-4,7,8,11-tetrahydrocyclodeca[b]furan; 4CN-2047; ZINC33831282; 57566-47-9; 19912-61-9; cyclodeca[b]furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E)-; (5E)-3,6,10-trimethyl-4,7,8,11-tetrahydrocyclodeca[b]furan; (5E,9E)-3,6,10-trimethyl-4,7,8,11-tetrahydrocyclodeca[b]furan; AC1NSVKM; Cyclodeca(b)furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (E,E)-; LS-55942; furanodiene; 3,6,10-Trimethyl-4,7,8,11-tetrahydro-cyclodeca[b]furan; Cyclodeca(b)furan, 4,7,8,11-tetrahydro-3,6,10-trimethyl-, (5E,9Z)-; InChI=1/C15H20O/c1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/h6-7,10H,4-5,8-9H2,1-3H3/b11-7+,12-6; Germacra-1(10),4,7,11-tetraene, 8,12-epoxy-, (Z,E)-

分子式:

C15H20O

Smiles:

CC1=CCC2=C(CC(=CCC1)C)OC=C2C

成分:

HBIN026855

OB_score:

45.113861

CAS_id:

19912-61-9

SymMap_id:

SMIT03401;SMIT15424

TCMID_id:

8013

TCMSP_id:

MOL000899;MOL001165;MOL004269

PubChem_id:

99117375


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000214 Rhizoma Curcumae 莪术 To promote the flow of qi and eliminate blood stasis with strong effect, and to relieve pain by removing the stagnation of undigested food./1. Its volatile oil and its components curcumenol, curdione and B-elemene destroy directly the Ehrlich-Ascites tumor and leukemia615 in mice. 2. Promoting phagocytosis of monocytes. 3. Dilating peripheral blood vessels, inhibiting aggregation of thrombocytes and thrombosis, and improving microcirculation.
TCMBANKHE003725 Rhizoma Zingiberis Recens 生姜 To induce perspiration and dispel cold, to warm the stomach and arret vomiting, and to resolve phlegm and relieve cough./Wind-cold common cold, fever and aversion to wind, headache and nasal congestion, vomiting, phlegm-rheum cough asthma, distention fullness, diarrhea.
TCMBANKHE003775 Radix Aconiti 川乌 To relieve rheumatic conditions and alleviate pain by warming the channels./Treatment of joint pain in rheumatic or rheumatoid arthritis, epigastric pain with cold sensation, or abdominal colic due to cold, also used as an analgesic in anaesthesis.
TCMBANKHE004664 Radix Codonopsis pilosulae 党参 To reinforce qi and invigorate the function of the spleen and the lung./Spleen-stomach vacuity, reduced food intake and sloppy stool, lassitude in limbs, cough and asthma due to lung vacuity, shortness of breath and spontaneous sweating, qi-blood depletion.
TCMBANKHE005005 Rhizoma Curcumae 广西莪术 Treatment of mass in the abdomen, amenorrhea due to blood stasis, distension and pain due to stagnation of undigested food, carcinoma of cervix at early stage./Treatment of mass in the abdomen, amenorrhea due to blood stasis, distension and pain due to stagnation of undigested food, carcinoma of cervix at early stage.
TCMBANKHE008491 Chloranthus serratus 及己 To quicken blood and dissipate stasis, dispel wind and relieve pain, resolve toxin and kill worms./Knocks and falls, fracture, amenorrhea, wind-damp impediment pain, clove boil, scab and lichen, itchy skin, poisonous snake bite.
TCMBANKHE009133 Radix Codonopsis pilosulae 西党;党参 Treatment of weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools, diabetes caused by internal heat;To reinforce qi and invigorate the function of the spleen and the lung./Treatment of weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools, diabetes caused by internal heat;Spleen-stomach vacuity, reduced food intake and sloppy stool, lassitude in limbs, cough and asthma due to lung vacuity, shortness of breath and spontaneous sweating, qi-blood depletion.
TCMBANKHE007736/XU-619 Chloranthus japonicus 银线草 陕西城关镇 To quicken blood and move stasis, dispel wind and eliminate damp, resolve toxin./Knocks and falls, wind-damp impediment pain, wind-cold common cold, swelling toxin sores, poisonous snake bites.
TCMBANKHE008098 Radix Curcumae 郁金 1. To invigorate blood and stop pain; 2. To promote qi circulation and release stagnation; 3. To cool blood and clear heat in the heart; 4. To relieve jaundice and facilitate gall bladder function/See Curcuma longa.
TCMBANKHE009030 Resi myrrhae;Myrrha 没药 1. To invigorate blood and stop pain; 2. To reduce swelling and promote healing/Stasis pain in chest and abdomen, amenorrhea, dysmenorrhea, concretion and conglomeration, knocks and falls, swollen welling abscess and sores, intestinal welling abscess, red eyes with gall.
TCMBANKHE003685/XU-724 Curcuma zedoaria 蓬莪术|莪术 广西省贵港市平南县
TCMBANKHE000590/XU-724 Curcuma zedoaria [Syn. Curcuma aeruginosa]|Curcuma zedoaria 莪术 广西省贵港市平南县 To break blood and dispel stasis, move qi and relieve pain, anticancer./Amenorrhea and dysmenorrhea, concretion conglomeration accumulation and gathering, food accumulation, distending pain in stomach duct and abdomen, indigestion, carcinoma of ovary, carcinoma of skin, genital carcinoma, malignant lymphoma, primary hepatoma, carcinoma of thyroid, carcinoma of stomach, carcinoma of lung.
TCMBANKHE007646/YNS-323/YEM-280 Chloranthus spicatus|Chloranthus spicatus (Thunb.) Makino|Chloranthus spicatus (Thunb.)Makino 金粟兰|珠兰 珠兰 云南药材标准:第五册|云南民族药物志:第二卷 除风活血,消肿止痛,接骨续筋,止血,用于风湿痹痛,筋脉拘挛,慢性腰腿痛,跌打损伤,骨折,外伤出血,月经不调,痛经,闭经,风寒感冒头痛,腹痛。|To dispel wind-damp, quicken blood and relieve pain, kill worms./Knocks and falls, migraine, intractable lichen. 傣族/哈尼族/瑶族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1