Compound Summary

  Compound Information

TCMBANKIN039472

药名:	rhynchophylline
别名:	SCHEMBL18779880; AKOS025402303; methyl (Z)-2-[(6'R,7'S)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate; AC-7977; Rhynchophylline; AC1NSX50; 76-66-4
分子式:	C22H28N2O4
Smiles:	CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O
成分:	HBIN042297
CAS_id:	77-66-4
SymMap_id:	SMIT01598;SMIT09756
TCMID_id:	18811
TCMSP_id:	MOL008469
PubChem_id:	137705801

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000418	Uncaria africana	非洲钩藤
TCMBANKHE000715	Uncaria guianensis	圭亚那钩藤
TCMBANKHE001023	Uncaria cordata	新型钩藤
TCMBANKHE001591	Uncaria attenuata	夏钩藤
TCMBANKHE001922	Uncaria acida	酸勾藤
TCMBANKHE001985	Mitragyna inermis
TCMBANKHE001992		钩藤根
TCMBANKHE002742	Uncaria callophylla	后夜钩藤
TCMBANKHE002816	Uncaria longiflora	长话钩藤
TCMBANKHE002833	Uncaria tomentosa	秘鲁钩藤
TCMBANKHE004268	Uncaria borneensis	婆罗洲钩藤
TCMBANKHE004610	Ramulus Uncariae cum Uncis	钩藤			To remove heat, subdue hyperactivity of the liver, and arrest convulsions./Infant fright wind and night crying, exuberant heat stirring wind, epilepsy of pregnancy, liver yang dizziness, liver fire headache.
TCMBANKHE007721	Exocarpium Benincasae	冬瓜皮			1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE007767	Semen Cavaliae	刀豆			To warm the stomach and check its upward adverse movement./Vacuity cold and hiccough, vomiting.
TCMBANKHE005874		玳玳花			Oppression in chest due to glomus, distending pain in stomach duct and abdomen, vomiting, reduced food intake.
TCMBANKHE008926	Uncaria lancifolia	披针叶钩藤
TCMBANKHE008750	Uncaria elliptica	椭圆钩藤
TCMBANKHE007551	Catechu	儿茶			To reduce toxic and to remove dampness./To arrest exudation, promote the growth of new tissue, and cure wounds.
TCMBANKHE007978	Uncaria sinensis	华钩藤			See Uncaria rhynchophylla./See Uncaria rhynchophylla.
TCMBANKHE008453	Uncaria hirsuta	毛钩藤
TCMBANKHE007889		杜仲叶			Lumbar and back pain, limp aching inability of legs and knees, hypertension.
TCMBANKHE006899/YNS-5/YEM-284/XU-215	Uncaria sessilifructus [Syn. Nauclea sessilifructus ]|Uncaria sessilifructus Roxb.|Uncaria sessilifructus	白钩藤	白钩藤	云南药材标准：第三册|云南民族药物志：第二卷|广西省来宾市金秀县六段村永新村	清火解毒，消肿止痛，除风通血。用于风湿病肢体关节红肿热痛或酸痛重着；风火气血不和所致的头目胀痛。	彝族
TCMBANKHE000261/YEM-443	Uncaria macrophylla Wall.	大叶钩藤根|大叶钩藤	大叶钩藤	云南民族药物志：第三卷		傣族/苗族/佤族/彝族/藏族/壮族
TCMBANKHE008324/YEM-443	Uncaria macrophylla|Uncaria macrophylla Wall.	大叶钩藤	大叶钩藤	云南民族药物志：第三卷	See Uncaria rhynchophylla./See Uncaria rhynchophylla.	傣族/苗族/佤族/彝族/藏族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000212	GRIN1	GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1	glutamate ionotropic receptor NMDA type subunit 1
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001506	ADRA1B	ADRA1; ALPHA1BAR	adrenoceptor alpha 1B
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006943	CHRM3	EGBRS; HM3; PBS	cholinergic receptor muscarinic 3
TCMBANKGE008702	OPRM1	LMOR; M-OR-1; MOP; MOR; MOR1; OPRM	opioid receptor mu 1
TCMBANKGE009455	CHRM5	HM5	cholinergic receptor muscarinic 5
TCMBANKGE014625	OPRD1	DOP; DOR; DOR1; OPRD	opioid receptor delta 1