Compound Summary


  Compound Information

药名:

psoralen

别名:

ZB004095; InChI=1/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6; 5-19-04-00445 (Beilstein Handbook Reference); s4737; A-Lactone; AK105376; 6-hydroxy-5-benzofuranacrylic acid gamma-lactone; Furocoumarin; Psoralen, >=99% (HPLC); 7H-Furo[3,2-g]chromen-7-one; KB-249864; MFCD00010520; Furo[4',5':6,7]coumarin; SMR000112587; 7H-Furo[3,2-g]benzopyran-7-one; Oprea1_841692; AKOS004110987; NSC404562; AX8034569; P2077; Manaderm (TN); AN-8451; C09305; LS-70690; Psoralene; FCH917722; EINECS 200-639-7; 6-Hydroxy-5-benzofuranacrylic acid beta-lactone; KS-00000KP0; ZCCUUQDIBDJBTK-UHFFFAOYSA-N; 7-furo[3,2-g]chromenone; ZINC120283; SC-18328; AC1L1M09; HSDB 3528; 7H-Furo[3,2-g][1]benzopyran-7-one; 2-Propenoic acid, 3-(6-hydroxy-5-benzofuranyl)-, delta-lactone; API0003973; 4CN-1081; AIDS038395; PHYTOALEXIN-CMPD; FT-0603268; Ficusin; UNII-KTZ7ZCN2EX; D00VUI; Furo[3,2-g]coumarin; 3-(6-Hydroxy-5-benzofuranyl)-2-propenoic Acid ; N1332; Psorline-P; MolPort-001-741-377; D08450; MEGxp0_001172; Furo[4',7]coumarin; 66-97-7; ANW-73223; CCRIS 4343; Psoralen; Bio-0831; SCHEMBL17835; KTZ7ZCN2EX; 5-Benzofuranacrylic acid, 6-hydroxy-, delta-lactone; CTK2F4103; Furo(3,2-g)-coumarin; Furo[2'.3':7.6]coumarin; BDBM50331544; psoralen ; 2H-furo[3,2-g]chromen-2-one; CS-3756; 7H-Furo(3,2-g)(1)benzopyran-7-one; MLS001304059; NSC-404562; TNP00293; HY-N0053; 3-(6-hydroxy-5-benzofuranyl)-2-propenoic acid delta-lactone; NCGC00017351-03; 7H-Furo[3,2-g]chromen-7-one #; AIDS-038395; furano[3,2-g]chromen-2-one; P-7850; NCGC00142529-01; NCGC00017351-02; 010P520; AC-7968; RTX-010528; 7H-Furo[3,2-g][1]benzopyran-7-one, 9CI; 6-hydroxy-5-benzofuranacrylic acid delta-lactone; CHEMBL164660; 6,7-Furanocoumarin; CHEBI:27616; NSC 404562; I06-0551; 5-Benzofuranacrylic acid, 6-hydroxy-, .delta.-lactone; C-07470; Furo(4',5',6,7)coumarin; MCULE-2236160968; 2-Propenoic acid, 3-(6-hydroxy-5-benzofuranyl)-, .delta.-lactone; Psoralene (DCF); BRD-K47264279-001-01-4; pyrano[5,6-f]benzofuran-7-one; ZINC00120283; Furo(2',3',7,6)coumarin; CC-34001; Psoralen, analytical standard; DTXSID00216205; BRN 0152784; Psolaren; ST057250; ACon1_001579; HMS2267L05; 7-furo[3,2-g][1]benzopyranone; furo[3,2-g]chromen-7-one; Furo[2',3':7,6]coumarin; P8399_SIGMA; W1301; Manaderm; 7H-furo[3,2-g]chromen-7-one; Psoralen, 97%; A835599; ST24045730; AJ-11687; NCGC00017351-01

分子式:

C11H6O3

Smiles:

C1=CC(=O)OC2=CC3=C(C=CO3)C=C21

成分:

HBIN041121

OB_score:

33.061306

CAS_id:

66-97-7

SymMap_id:

SMIT00134

TCMID_id:

18072

TCMSP_id:

MOL001950

PubChem_id:

6199


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001687 大皂荚
TCMBANKHE001957 砂糖
TCMBANKHE002428 Radix Glehniae 沙参 Treatment of: 1. Deficient yin of the lungs with heat manifested as dry cough or cough with scanty sputum, hoarse voice from a chronic cough, dry throat and thirst. Glehnia root (Shashen) is used with Ophiopogon root (Maidong) and Tendrilled fritillary bulb (Chuanbeimu). 2. Body fluids consumed by febrile diseases manifested as dry tongue and poor appetite. Glehnia root (Shashen) is used with Ophiopogon root (Maidong), Fresh rehmannia root (Shengdihuang) and Fragrant solomonseal rhizome (Yuzhu) in the formula Yiwei Tang./Treatment of: 1. Deficient yin of the lungs with heat manifested as dry cough or cough with scanty sputum, hoarse voice from a chronic cough, dry throat and thirst. Glehnia root (Shashen) is used with Ophiopogon root (Maidong) and Tendrilled fritillary bu
TCMBANKHE003461 紫花前胡
TCMBANKHE003849 Levisticum officinale 欧当归 To quicken blood and regulate menstruation, disinhibit urine./Amenorrhea, dysmenorrhea, dizziness, headache, numbness in limbs, edema.
TCMBANKHE008512 radix Peucedani 前胡 To dispel wind and remove heat, and to relieve cough and resolve phlegm ./Cough, externally contracted wind-heat, lung heat phlegm depression, cough and asthma with abundant phlegm, sticky phlegm, retching counterflow and reduced food intake, fullness and oppression in chest and diaphragm.
TCMBANKHE008975 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE006184 Radix Angelicae Pubescentis 独活 To relieve rheumatic conditions, and to remove obstruction from the channels and relieve pain./Wind-cold-damp impediment (especially in lower part of body), pain in lumbus and knees, headache, toothache.
TCMBANKHE005146 Psilotum nudum 石刷把 To dispel wind and eliminate damp, quicken blood and stanch bleeding./Wind-damp impediment pain, wind papules, amenorrhea, blood ejection, knocks and falls.
TCMBANKHE005182 Changium smyrnioides 明党参 To moisten lung and transform phlegm, nourish yin and harmonize stomach, resolve toxin./Lung heat cough, vomiting nausea, reduced food intake with dry mouth, anemia, dizziness, leukorrhea, clove toxin sores.
TCMBANKHE005219 Heracleum lanatum 软毛独活 See Angelica pubescens f. biserrata ./See Angelica pubescens f. biserrata.
TCMBANKHE005444 白鲜皮 To clear heat and dry damp, dispel wind and relieve itch, resolve toxin./1. Inhibiting the growth of pathogenic fungi. 2. Its infusion lowers vaccine-induced fever in rabbits. 3. Dictamnine, one of its active components, increase the myocardial tone of frogs. Dermatitis, psoriasis, icterohepatitis, damp-heat sore and papules, profuse pus, yellow-water sore, damp ulceration on skin, itchy skin, damp-heat jaundice, damp-heat impediment.
TCMBANKHE008227 Ficus simplicissima 粗叶榕 To fortify spleen and supplement lung, move qi and disinhibit damp, soothe sinews and quicken network vessels./Spleen vacuity edema, reduced food intake with fatigue, tuberculosis with cough, vaginal discharge, night sweating, postpartum scant milk, wind-damp impediment pain, edema, cirrhosis with ascites, hepatitis, knocks and falls.
TCMBANKHE008047 Ruta graveolens 臭草 To dispel wind, abate fever, disinhibit urine, quicken blood, resolve toxin, disperse swelling./Common cold with fever, wind-damp bone pain, infant fright wind, inhibited urination, diarrhea, mounting qi, amenorrhea, knocks and falls, heat toxin sores, eczema.
TCMBANKHE006060 Herba Hyperici Japonici 地耳草 1.To deprive dampness and relieve jaundice. 2. To clear away heat and toxic material. 3. To promote blood circulation and relieve edema./Damp-heat jaundice, diarrhea, dysentery, intestinal welling abscess, pulmonary welling abscess, swelling toxin of welling abscess and boil, nipple moth, mouth sore, red eyes with gall, poisonous snake bite, knocks and falls.
TCMBANKHE006755 Herba Hyperici japonici 田基黄;地耳草 1.To deprive dampness and relieve jaundice. 2. To clear away heat and toxic material. 3. To promote blood circulation and relieve edema./Damp-heat jaundice, diarrhea, dysentery, intestinal welling abscess, pulmonary welling abscess, swelling toxin of welling abscess and boil, nipple moth, mouth sore, red eyes with gall, poisonous snake bite, knocks and falls.
TCMBANKHE007163 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE007459 Peucedanum praeruptorum 白花前胡 See Angelica decursiva ./See Angelica decursiva.
TCMBANKHE006236/XU-723 Psoralea corylifolia 补骨脂 云南省西双版纳勐腊县 To supplement kidney and invigorate yang , accept qi and calm asthma, warm spleen and check diarrhea./Fracture, osteomalacia, osteoporosis, kidney yang vacuity, cold pain in lumbus and knees, impotence and emission, frequent urination, enuresis, kidney qi insecurity, vacuity asthma, spleen-kidney vacuity, chronic diarrhea, white patch wind, alopecia areata, psoriasis.
TCMBANKHE002976/XU-723 Fructus Psoraleae Corylifoliae|Psoralea corylifolia 破故纸|补骨脂 云南省西双版纳勐腊县 Treatment of impotence, seminal emission, enuresis, frequent urination, aching of the loins and knees with cold sensation, asthma in deficiency syndromes of the kidney, diarrhea occurring before dawn daily. External use for vitiligo and alpecia areata./1. Corylifolinin ( isobavachalcone ) dilates coronary artery significantly. 2. Promoting phagocytosis of macrophage. 3. Exciting the intestinal smooth muscles in vivo or in vitro, and relaxing the uterus of guinea-pigs in vitro.
TCMBANKHE007824/YEM-258/XU-654 Ficus carica|Ficus carica L.|Ficus carica Linn. 无花果 无花果 云南民族药物志:第二卷|云南省曲靖市宣威市 To clear heat and engender liquid, fortify spleen and promote digestion, resolve toxin and disperse swelling./Swelling pain in throat, dry cough with hoarseness, scant breast milk, intestinal heat and constipation, inappetence, indigestion, diarrhea, dysentery, swollen welling abscess, lichen. 傣族/哈尼族/苗族/佤族
TCMBANKHE007614/YEM-258/XU-654 Ficus carica|Ficus carica L.|Ficus carica Linn. 无花果叶|无花果 无花果 云南民族药物志:第二卷|云南省曲靖市宣威市 To clear damp heat, resolve sore toxin, disperse swelling and relieve pain./Damp-heat diarrhea, vaginal discharge, hemorrhoids, pain from swollen welling abscess, scrofula. 傣族/哈尼族/苗族/佤族
TCMBANKHE006781/YEM-333 Radix Saposhnikoviae divaricatae|Saposhnikovia divaricata (Turcz.)Schischk. 防风 防风 云南民族药物志:第二卷 To induce diaphoresis, to dispel wind, to alleviate rheumatic conditions, and to relieve spasm./Migraine, headache and generalized pain, common cold, rheumatoid arthritis, externally contracted wind-cold, wind-damp impediment pain, aching pain in joints, abdominal pain and diarrhea, intestinal wind bleeding, tetanus, wind papule itching, sores. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE005203/YEM-999/XU-341 Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica 板蓝根|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess. 回族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000053 NFKB1 CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB nuclear factor kappa B subunit 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000298 SOD1 ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer superoxide dismutase 1
TCMBANKGE000311 JUND AP-1 JunD proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000312 JUNB AP-1 JunB proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000466 CYP2A6 CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB cytochrome P450 family 2 subfamily A member 6
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000986 ERBB2 CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 erb-b2 receptor tyrosine kinase 2
TCMBANKGE000990 EGFR ERBB; ERBB1; HER1; NISBD2; PIG61; mENA epidermal growth factor receptor
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001181 TGFB1 CED; DPD1; IBDIMDE; LAP; TGF-beta1; TGFB; TGFbeta transforming growth factor beta 1
TCMBANKGE001197 FOS AP-1; C-FOS; p55 Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE004609 CCS - copper chaperone for superoxide dismutase
TCMBANKGE006147 EFEMP1 DHRD; DRAD; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5 EGF containing fibulin extracellular matrix protein 1
TCMBANKGE008172 MAOA BRNRS; MAO-A monoamine oxidase A
TCMBANKGE012003 KCNC1 EPM7; KV3.1; KV4; NGK2 potassium voltage-gated channel subfamily C member 1
TCMBANKGE013582 SOD3 EC-SOD superoxide dismutase 3
TCMBANKGE014473 CRH CRF; CRH1 corticotropin releasing hormone