Compound Summary


  Compound Information

药名:

norbergenin

别名:

norbergenin; DTXSID30229787; AC1Q6O1D; AC1L2JFB; norbergenin ; AIDS071138; Pyrano(3,2-c)(2)benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,9,10-pentahydroxy-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,4aalpha,10bbeta))-; (2S,3R,4R,4aS,10bR)-3,4,8,9,10-pentahydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one; CTK5E6939; (2s,3r,4r,4as,10br)-3,4,8,9,10-pentahydroxy-2-(hydroxymethyl)-3,4,4a,10b-tetrahydropyrano[3,2-c]isochromen-6(2h)-one; (2S,3R,4R,4aS,10bR)-3,4,8,9,10-pentahydroxy-2-methylol-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one; 79595-97-4; AIDS-071138; CHEMBL463164

分子式:

C13H14O9

Smiles:

c1(O[H])c(O[H])c([C@]([H])(O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]2([H])O[H])[C@]2([H])OC3=O)c3c([H])c1O[H]

成分:

HBIN037299

OB_score:

13.398309

CAS_id:

79595-97-4

SymMap_id:

SMIT11927;SMIT16901

TCMID_id:

15710

TCMSP_id:

MOL010965

PubChem_id:

73192


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004154 Ardisiae japonicae 矮地茶 1. To eliminate phlegm and relieving cough.2. To promote diuresis to deprive dampness. 3. To activate blood circulation and stop bleeding./1. Bergenin, an active comonent, is an expectorant. 2. Its volatile oil or flavone can relieve bronchospasm induced by histamine in vitro. 3. Its decoction inhibits the growth of Pneumococcus, Staphylococcus aureus and influenza virus in vitro.
TCMBANKHE004610 Ramulus Uncariae cum Uncis 钩藤 To remove heat, subdue hyperactivity of the liver, and arrest convulsions./Infant fright wind and night crying, exuberant heat stirring wind, epilepsy of pregnancy, liver yang dizziness, liver fire headache.
TCMBANKHE004907 连钱草 Treatment of acute urinary infection, urolithiasis, acute jaundice, painful swelling in sores and carbuncies, traumatic injuries.
TCMBANKHE005198 Herba Saxifragae 虎耳草 For clearing heat and removing toxic substances/Wind papules, eczema, otitis media, erysipelas, cough with blood ejection, pulmonary welling abscess, flooding and spotting, hemorrhoids.
TCMBANKHE005391 Ardisia colorata 有色紫金牛
TCMBANKHE006568/YEM-730/XU-328 Woodfordia fruticosa|Woodfordia fruticosa(L.)Kurz 虾子花 虾子花 云南民族药物志:第四卷|云南省玉溪市峨山县化念镇 To quicken blood and stanch bleeding, soothe sinews and quicken network vessels./Dysmenorrhea, menstrual block, flooding, nosebleed(epistaxis), coughing of blood, intestinal wind bleeding, dysentery, wind-damp impediment pain, taxation damage in lumbar muscle, knocks and falls. 傣族/哈尼族/彝族
TCMBANKHE005665/YNS-322/YEM-953/XU-212 Ardisia crenata|Ardisia crenata Sims 朱砂根 朱砂茎叶|朱砂根 云南药材标准:第四册|云南民族药物志:第五卷|广西省桂林市荔浦县蒲芦乡天河瀑布景区外 清热宁心,养血活血,利咽明目。用于口糜,咽喉肿痛,胁肋痞痛,视物模糊,心悸失眠;风湿痹痛,跌倒损伤|To clear heat and resolve toxin, quicken blood and relieve pain./Swelling pain in throat, wind-damp-heat impediment, jaundice, dysentery, knocks and falls, fire flow, mastitis, testitis. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/佤族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1