Compound Summary


  Compound Information

药名:

orientin

别名:

28608-75-5; Orientin; CHEBI:7781; luteolin-8-C-beta-D-glucopyranoside; Lutexin; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]-4-chromenone; AIDS026706; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]chromone; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one; Luteolin 8-C-glucoside; 2-(3,4-dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one; 8-beta-D-glucosylluteolin; 2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one; C10114; LMPK12110470; AIDS-026706; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-.beta.-D-glucopyranosyl-5,7-dihydroxy-; Orientin (Flavone); Luteolin 8-C-beta-D-glucopyranoside; Luteolin 8-glucoside; 8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone

分子式:

C21H20O11

Smiles:

C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O)O

成分:

HBIN038267

OB_score:

1.78986

CAS_id:

28608-75-5

SymMap_id:

SMIT00199

TCMID_id:

16185

TCMSP_id:

MOL004178

PubChem_id:

5281675


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000372 Siegesbeckia orientalis 希莶 To dispel wind-damp, free channels and network vessels, clear heat and resolve toxin./Wind-damp impediment pain, lassitude in lumbus and knees, hemiplegia, hypertension, malaria, jaundice, swelling toxin of welling abscess and sore, wind papules, damp sore, animal and insect bites.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE002553 荭草花
TCMBANKHE003347 西草
TCMBANKHE003778 Lythrum salicaria 千屈菜 To clear heat and resolve toxin, promote contraction and stanch bleeding./Dysentery, diarrhea, hematochezia, flooding, ulcerating sores, blood ejection, spontaneous external bleeding, bleeding due to external injury.
TCMBANKHE003938 Linum usitatissimum 亚麻 To calm liver, quicken blood./Liver wind headache, knocks and falls, swollen welling abscess and clove sores.
TCMBANKHE003967 Radix Platycodi 桔梗 To relieve cought, to soothe sore throat, and to promote expectoration and discharge of pus./Cough with profuse phlegm, swelling pain in throat, pulmonary welling abscess with hacking of pus and blood, fullness in chest and rib-side pain, dysentery, dribbling urinary block.
TCMBANKHE006277 Rabdosia nervosa 显脉香茶菜 To disinhibit damp and harmonize stomach, resolve toxin and close sores./Acute hepatitis, indigestion, pemphigus, eczema, itchy skin, burns and scalds, poisonous snake bites.
TCMBANKHE006021 Semen Sesami Nigrum 黑芝麻 To tonify the liver and the kidney, to replenish vital essence and blood, and to relax the bowels./Dizziness, tinnitus and deafness, premature graying in beard and hair, hair loss during convalescence, intestinal dry and constipation.
TCMBANKHE004711 Rabdosia rubescens 冬淩草 To clear heat and resolve toxin, quicken blood and relieve pain, anticancer./Swelling pain in throat, common cold with headache, trachitis, chronic hepatitis, pain in joints due to rheumatalgia, snake or insect bites, carcinoma of mammary glands, carcinoma of esophagus.
TCMBANKHE009013 Cortex Illicii 地枫皮 To relieve rheumatic conditions, and to promote the flow of qi and relieve pain./Pain in joints due to rheumatalgia, taxation damage in lumbar muscle, centipede bite.
TCMBANKHE004791 Herba Spirodelae 浮萍 To dispel wind-heat, to promote eruption, and to cause diuresis./Wind-heat exterior syndrome, non-eruption of measles, dormant papules with pruritus, edema, dribbling urinary block, sore and lichen, erysipelas, scalds.
TCMBANKHE004863 Trollius macropetalus 长瓣金莲花 To clear heat and resolve toxin./Infection of upper respiratory tract, acute or chronic tonsillitis, acute conjunctivitis, acute otitis media, acute lymphangitis, acute dysentery, acute appendicitis.
TCMBANKHE004912 Flos Caryophylli 丁香 To warm the spleen and stomach, to regulate the adverse flow of the stomach qi, and to restore the kidney yang./Stomach cold with retching counterflow, hiccough, cold pain in stomach duct and abdomen, reduced food intake and diarrhea, kidney vacuity impotence, vacuity cold in lumbus and knees, yin flat abscess.
TCMBANKHE005226 Rhizoma Dryriae 骨碎补 To replenish the kidney, to strengthen the bones, to promote the healing of fracture, and to relieve pain./Kidney vacuity lumbago, tinnitus and deafness, tooth mobilizing, wrenching and contusion from knocks and falls, sinew and bone wound, alopecia areata, white patch wind.
TCMBANKHE005884 Linum usitatissimum To calm liver, quicken blood./Liver wind headache, knocks and falls, swollen welling abscess and clove sores.
TCMBANKHE005729 Semen Euphorbiae 千金子 To cause drastic purgation for treating edema, and eliminate blood stasis for treating masses./Edema, phlegm-rheum, accumulation and distention-fullness, urinary and fecal stoppage, amenorrhea due to blood stasis, intractable impediment, wart.
TCMBANKHE005736 Herba Commelie 鸭跖草 1. Clear away heat and toxic materials. 2. Clear away heat and promote diuresis. /Common cold, wind-heat common cold, influenza, noninfectious fever, ardent fever incessant, ascites, edema, hordeolum, swelling pain in throat, scant urine with edema, heat strangury with inhibited pain, swollen welling abscess and toxin of clove.
TCMBANKHE007912 豨莶草
TCMBANKHE005940 Vitex rotundifolia [Syn. Vitex trifollia var. simplicifolia ] 单叶蔓荆
TCMBANKHE009129 Flos Trollii chinensis 金莲花 For clearing heat and removing toxic substances/Common cold with fever, swelling pain in throat, mouth sore, gum swelling and pain, gum hemorrhage, red eyes with gall, swelling toxin of clove sore, acute periostitis, acute lymphangitis.
TCMBANKHE006352 Abrus Precatorius L. 相思子 Vomiting, welling abscess, parotitis, scab and lichen, wind-damp bone pain.
TCMBANKHE007206 Lignum Santaii Albi 檀香 To promote the flow of qi in the heart, to warm the spleen and stomach, to increse appetite, and to relieve pain./Pain in chest and abdomen, cold stomachache, vomiting of water due to congealing cold qi stagnation, coronary heart disease with pattern of qi stagnation and blood stasis.
TCMBANKHE007176 Fagopyrum tataricum 苦荞麦
TCMBANKHE008279 山楂叶 Hypertension, lacquer sore, enduring sores.
TCMBANKHE009034 Fructus Polygoni Orientalis 水红花子 To reduce masses by dissipating blood stasis, and to relieve pain by removing stagnancy of food./Treatment of mass in the abdomen, goitre with pain, epigastric pain and distension due to indigestion.
TCMBANKHE003788/XU-329 Lespedeza bicolor 胡枝子 广西省桂林市资源县 To clear heat and moisten lung, disinhibit urine and free strangury, stanch bleeding./Lung heat cough, common cold with fever, pertussis, strangury syndrome, spontaneous external bleeding, blood ejection, hematuria, hematochezia.
TCMBANKHE005716/YEM-243 Semen Canbis;Fructus Canbis;Fructus cannabis|Cannabis sativa L. 火麻仁;麻子仁|大麻 大麻 云南民族药物志:第二卷 To cause Taxation.;Purging by moisterizing/Blood and liquid depletion, intestinal dry and constipation. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE004801/YEM-339 Herba Verbae|Verbena officinalis L. 马鞭草 马鞭草 云南民族药物志:第二卷 To promote the flow of blood and to relieve blood stasis, to stop malarial attacks, to counteract toxicity, and to cause diuresis./Malaria, amenorrhea and dysmenorrhea, throat impediment, edema, heat strangury, diphtheria, bilharziosis, dysentery, concretion conglomeration accumulation and gathering. 白族/布朗族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/纳西族/普米族/佤族/彝族/藏族/壮族
TCMBANKHE008080/YEM-568 Fagopyrum esculentum|Fagopyrum esculentum Moench 荞麦秸|荞麦 甜荞 云南民族药物志:第三卷 To precipitate qi and disperse accumulation, clear heat and resolve toxin, stanch bleeding, lower blood pressure./Dysphagia-occlusion, indigestion, dysentery, vaginal discharge, swollen welling abscess, scalds, hemoptysis, purpura, hypertension. 哈尼族/佤族/彝族
TCMBANKHE005333/YEM-568 Fagopyrum esculentum|Fagopyrum esculentum Moench 荞麦 甜荞 云南民族药物志:第三卷 To fortify spleen and disperse accumulation, precipitate qi and loosen intestines, resolve toxin and close sores./Gastrointestinal accumulation, diarrhea, dysentery, intestine gripping sand, white turbidity, vaginal discharge, spontaneous sweating, night sweating, zoster, erysipelas, effusion of back from welling abscess and flat abscess, scrofula, burns and scalds. 哈尼族/佤族/彝族
TCMBANKHE007732/YEM-576 Kyllinga brevifolia|Kyllinga brevifolia Rottb. 水蜈蚣|短叶水蜈蚣 水蜈蚣 云南民族药物志:第三卷 To course wind and resolve exterior, clear heat and disinhibit damp, quicken blood and resolve toxin./Common cold with headache and fever, acute bronchitis, pertussis, malaria, jaundice, dysentery, chyluria, toxin swelling of sores, itchy skin, poisonous snake bite, knocks and falls, rheumatic arthritis. 哈尼族/基诺族/傈僳族/苗族
TCMBANKHE006147/YEM-616 Tamarindus indica|Tamarindus indica L. 酸角|酸豆 酸角 云南民族药物志:第三卷 To clear heat and resolve toxin, harmonize stomach and disperse accumulation./Summerheat stroke, inappetence, child gan accumulation, vomiting in pregnancy, constipation. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/佤族
TCMBANKHE004426/YEM-669 Cucumis sativus|Cucumis sativus L. 黄瓜 黄瓜 云南民族药物志:第四卷 To clear heat, disinhibit water, resolve toxin./Febrile diseases thirst, short voidings of reddish urine, burns and scalds, scant urine with edema, sweat macule, prickly heat. 傣族/哈尼族/佤族/彝族
TCMBANKHE008148/YEM-669 Cucumis sativus|Cucumis sativus L. 黄瓜 黄瓜 云南民族药物志:第四卷 To clear heat, disinhibit water, resolve toxin./Febrile diseases thirst, short voidings of reddish urine, burns and scalds, scant urine with edema, sweat macule, prickly heat. 傣族/哈尼族/佤族/彝族
TCMBANKHE008890/YEM-811 Polygonum orientale|Polygonum orientale L. 红草|红蓼 水红花子 云南民族药物志:第四卷 To dispel wind and eliminate damp, clear heat and resolve toxin, quicken blood, interrupt malaria./Infections, rheumatic arthritis, malaria, mounting qi, beriberi, swelling of sores. 哈尼族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE001132 BAX BCL2L4 BCL2 associated X, apoptosis regulator
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2