Compound Summary

  Compound Information

TCMBANKIN041285

药名:	Bryonolic acid
别名:	bryonolicacid; bryonolate; D:C-friedoolean-8-en-3beta-ol-29-oic acid; (2R,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10-Hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,2,3,4,4a,5,6,6a,7,8,8a,9,10,11,12,12a,13,14,14a,14b-eicosahydro-picene-2-carboxylic acid; AIDS-075058; 24480-44-2; bryonolic acid; AIDS075058; (2R,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,13,14,14b-tetradecahydropicene-2-carboxylic acid
分子式:	C30H48O3
Smiles:	C1([H])([H])C([H])([H])[C@](C([H])([H])[H])(C(C([H])([H])C([H])([H])[C@@](C([H])([H])[H])([C@]([H])(C([H])([H])[C@@](C(O[H])=O)(C([H])([H])[H])C([H])([H])C2([H])[H])[C@@]2(C([H])([H])[H])C([H])([H])C3 ([H])[H])[C@]34C([H])([H])[H])=C4C([H])([H])C5([H])[H])[C@]5([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]1(O[H])[H]
成分:	HBIN018935
OB_score:	16.881849
CAS_id:	24480-44-2
SymMap_id:	SMIT08325;SMIT14509;SMIT19037
TCMID_id:	26238;2687
TCMSP_id:	MOL006757
PubChem_id:	472768

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003755	Radix Ampelopsis	白蔹			To remove toxic heat, to cure carbuncles, and to reduce nodules./Swelling toxin of sore and welling abscess, burns and scalds, scrofula, damp sore, warm malaria, frightepilepsy, blood dysentery, intestinal wind, hemorrhoids and fistulas, leukorrhea, knocks and falls, bleeding due to external injury.
TCMBANKHE004317	Trichosanthes hupehensis	湖北瓜蒌
TCMBANKHE005221	Semen Ginkgo	白果			1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE008343	Radix Trichosanthis	天花粉			To remove heat, to promote the production of body fluid, and to facilitate the drainage of pus and the subsidence of swelling./Febrile diseases thirst, lung heat dry cough, diabetes mellitus due to internal heat, toxin swelling of sores, induce abortion.
TCMBANKHE008354	Semen Ginkgo	白果			1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE008807	Trichosanthes hupehensis	湖北瓜蒌
TCMBANKHE007751	Cortex Fraxini	秦皮			To remove damp-heat, to arrest discharges, and to improve eyesight./1. Inhibiting the growth of dysentery bacillus and staphylococcus.2. Antitussive and expectorant.3. Aesculin, one of its active components, prolongs the hypnotic effect of hexobarbital in mice.4. Aescuktin, another active component, exerts an antihistaminic effect and relaxes smooth muscles of guinea-pig's trachea in vitro.5. Analgesic. The effect of aescuktin is stronger than that of aspirin but weaker than codeine.
TCMBANKHE006421/YEM-1037/XU-804	Trichosanthes kirilowii Maxim.|Trichosanthes kirilowii	瓜蒌|栝楼	天花粉	云南民族药物志：第五卷|云南省昭通市盐津县	Angina pectoris, lung heat cough, chest impediment, diabetes mellitus, acute mastitis, constipation, swelling toxin of welling abscess and sore.	苗族/彝族
TCMBANKHE006143/YEM-213	Luffa cylindrica|Luffa cylindrica(L.)Roem.	丝瓜	丝瓜	云南民族药物志：第二卷	To clear heat and resolve phlegm, cool blood and resolve toxin./Febrile diseases with vexation and thirst, cough of phlegm asthma, intestinal wind bleeding, bleeding from hemorrhoids, blood strangury, flooding and spotting, sores with welling abscess and flat abscess, galactostasis, innominate toxin swelling, edema.	阿昌族/傣族/德昂族/景颇族/傈僳族/水族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor