Compound Summary

  Compound Information

TCMBANKIN041527

药名:	Chrysophanol-8-O-beta-D-(6'-O-galloyl)-glucopyranoside
别名:	[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(8-hydroxy-6-methyl-9,10-dioxo-1-anthryl)oxy]tetrahydropyran-2-yl]methyl 3,4,5-trihydroxybenzoate; 3,4,5-trihydroxybenzoic acid [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(8-hydroxy-6-methyl-9,10-dioxo-1-anthryl)oxy]-2-tetrahydropyranyl]methyl ester; [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(8-hydroxy-6-methyl-9,10-dioxo-anthracen-1-yl)oxy-oxan-2-yl]methyl 3,4,5-trihydroxybenzoate; Chrysophanol 8-(6-O-galloyl-beta-D-glucopyranoside); [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(8-hydroxy-6-methyl-9,10-dioxoanthracen-1-yl)oxyoxan-2-yl]methyl 3,4,5-trihydroxybenzoate; 3,4,5-trihydroxybenzoic acid [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(8-hydroxy-9,10-diketo-6-methyl-1-anthryl)oxy]tetrahydropyran-2-yl]methyl ester; chrysophanol-8-o-beta-d-(6'-o-galloyl)-glucopyranoside; AC1NSTKE; CHEMBL109609
分子式:	C28H24O13
Smiles:	CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3OC4C(C(C(C(O4)COC(=O)C5=CC(=C(C(=C5)O)O)O)O)O)O
成分:	HBIN020483
OB_score:	1.920344
SymMap_id:	SMIT04526;SMIT19137
TCMID_id:	30775
TCMSP_id:	MOL002245
PubChem_id:	5315852

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004552	Rumex dentatus	牛舌草			To clear heat and resolve toxin, kill worms and relieve itch./Red swollen breast.
TCMBANKHE001849		倒扣草
TCMBANKHE003063	Herba Plantaginis	车前草			To remove heat and to induce diureses, to promote expectoration, to reduce heat in blood and to counteract toxicity./Treatment of edema with oliguria, urinary infection with difficult painful urination, diarrhea caused by summer-damp, cough caused by phlegm-heat, spitting of blood, epistaxis, carbuncles and sores.
TCMBANKHE003373	Exocarpium Citri grandis	化橘红			To dispel cold, eliminate damp and phlegm, and arrest emesis or nausea./Treatment of cough, itching of the throat and profuse expectoration in colds, nausea, vomiting and epigastric distension caused by improper diet or excessive drinking.
TCMBANKHE003426	Fructus Leonuri	茺蔚子			To activate blood circulation and regulate menstruation, to subdue hyperactivity of the liver, and to clear the eye of opacity./Treatment of menstrual disorders, amenorrhea, hysmenorrhea, inflammation of the eye with formation of corneal opacity, dizziness and headache.
TCMBANKHE003723	Flos Lonicerae	金银花			To remove toxic heat and dispel wind-heat./Infection of upper respiratory tract, tonsillitis, acute laryngitis, skin suppurations, welling abscess, viral conjunctivitis, influenza, pneumonia, mastitis, acute appendicitis, warm disease fever, heat toxin blood dysentery, swollen welling abscess and clove sores, throat impediment.
TCMBANKHE003732	Ganoderma Lucidum seu Japonicum	灵芝(赤芝）			Hyperlipemia, coronary heart disease, angina pectoris, septicemia, carcinoma, hepatitis, vacuity taxation, palpitation, insomnia, dizziness, fatigue hypodynamia, enduring cough and asthma, chronic bronchitis, silicosis.
TCMBANKHE003738	Aloe	芦荟			1. To purge feces; 2. To clear heat in the liver; 3. To kill worms/Constipation, child gan accumulation, ascariasis, fright wind, lichen.
TCMBANKHE003822	Rumex patientia	牛西西			To clear heat and resolve toxin, stanch bleeding and disperse swelling, free stool and kill worms./Blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, red and white vaginal discharge, purpura, dysentery, hepatitis, constipation, inhibited urination, swelling toxin of welling abscess and sore, scab and lichen, knocks and falls, burns and scalds.
TCMBANKHE003911	Folium Sene	番泻叶			To purge feces downward/Heat bind and accumulation, constipation w ith abdominal pain, edema distention fullness.
TCMBANKHE004160	Semen Cassiae;Semen Sene	决明子			To remove heat from the liver, to improve eyesight, and to relax bowels./See Cassia obtusifolia.
TCMBANKHE004287	Radix Achyranthis bidentatae	牛膝			To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat.
TCMBANKHE006135	Rheum wittrocki	天山大黄
TCMBANKHE006313	Radix et Rhizoma Rhei	大黄			To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.
TCMBANKHE008555	Polygonum multiflorum	何首乌			To lower cholesterol, enrich yin and nourish blood, moisten intestines and free stool, interrupt malaria, dispel wind, resolve toxin./Backache, neurasthenia, hyperlipemia, neurosis, insomnia, dizziness due to anemia, palpitation, limp aching lumbus and knees due to liver kidney yin vacuity, premature graying in beard and hair, tinnitus, emission, intestinal dry and constipation, enduring malaria, wind papule itching, sore and welling abscess, scrofula, hemorrhoids.
TCMBANKHE004797	Rhamnus purshiana	波希鼠李
TCMBANKHE005538	Hemerocallis citrina	黄花菜			To clear heat and disinhibit damp, loosen chest and resolve depression, cool blood and resolve toxin./Short voidings of reddish urine, jaundice, oppression in chest and vexation in heart, reduced sleep, hematochezia from hemorrhoids, sore and welling abscess.
TCMBANKHE005748	Rheum tanguticum	唐古特大黄			See Rheum officinale./See Rheum officinale.
TCMBANKHE006028	Rhamnus davurica	鼠李			To clear heat and resolve toxin, drain precipitation and kill worms, relieve cough and dispel phlegm./Sore and welling abscess, scrofula, scab and lichen, decayed toothache, mout h sore, abdominal distention and constipation, cough of phlegm asthma, edema distention fullness.
TCMBANKHE006054	Radix chuanxiong;Rhizoma Chuanxiong	川芎			1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE008745	Cassia acutifolia	尖叶番泻叶			See Cassia angustifolia ./See Cassia angustifolia .
TCMBANKHE008104	Radix chuanxiong;Rhizoma Chuanxiong	川芎			1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE005418/YNS-102	Rhizoma Polygoni cuspidati|Polygonum cuspidatum Sieb.et Zucc.	虎杖	虎杖叶	云南药材标准：第一册	平肝潜阳，祛痰息风。用于肝阳上亢，血压偏高，头晕头昏|To dispel wind and damp, to eliminate blood stasis and alleviate pain, to relieve cough, and to resolve phlegm./Hyperlipemia, impediment pain in joints, damp-heat jaundice, toxic jaundice, child jaundice, amenorrhea, hepatitis, appendicitis, candida vaginitis, concretion and conglomeration, cough with profuse phlegm, burns and scalds, knocks and falls, swelling toxin of welling abscess and sore.
TCMBANKHE008911/YEM-126	Radix Achyranthis bidentatae|Achyranthes bidentata Blume	牛膝;怀牛膝|牛膝	牛膝	云南民族药物志：第一卷	To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward.Treament of soreness of the lumbar and knee joints with weakness inthe legs, amenorrhea with mass formation in the abdomen, dizziness due to hyperactivity of the liver./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat.	阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE006959/YNS-135/YEM-14	Semen Cassiae;Semen Sene|Cassia tora Linn.|Cassia tora L.	决明子;草决明|决明	决明根|草决明	云南药材标准：第三册|云南民族药物志：第一卷	安神补脑，清肝明目，理气止痛。主治失眠多梦，入睡易惊，腹内痉挛剧痛，腹部包块，黄疸，疟疾。|To remove heat from the liver, to improve eyesight, and to relax bowels.Treatment of inflammation in the eye with pain, photophobia and lacrimination, headache, dizziness, blurred vision and constipation./See Cassia obtusifolia.1. Oral adminstration of the hearbal powder can inhibit the rising of serum cholesterol and formation of atherosclerosis in rabbits.2. Its tincture and infusion can inhibit the myocardium of toad in vitro, and contract th eblood vessels of lower limbs.3. Its infusion can lower the blood pressure in dogs, cats and rabbits.4. Chrysophanol, one of the active components, is a laxative.5. Bacteriostatic.	傣族/基诺族/拉祜族/傈僳族/苗族/佤族/彝族/藏族
TCMBANKHE005278/YEM-158	Cassia occidentalis|Cassia occidentalis L.	望江南	望江南	云南民族药物志：第一卷	To clear lung, clear liver, calm asthma, disinhibit urine, free stool, resolve toxin and disperse swelling, lower blood pressure./Cough and asthma, hypertension, headache and red eyes, dribbling urination, constipation, swelling toxin of welling abscess and sore, snake or insect bites.	阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE005460/YEM-471/XU-441	Tectona grandis|Tectona grandis L.f.	柚木	柚木	云南民族药物志：第三卷|云南省德宏州盈江县那邦镇铜壁关自然保护区	To harmonize center and check vomiting, dispel wind and relieve itch./Nausea and vomiting, wind papule itching.	傣族
TCMBANKHE006999/YEM-606	Rumex japonicus|Rumex nepalensis Spreng.	羊蹄|尼泊尔酸模	土大黄	云南民族药物志：第三卷	To clear heat and free stool, cool blood and stanch bleeding, kill worms and relieve itch./Constipation, blood ejection, spontaneous external bleeding, intestinal wind bleeding, bleeding from hemorrhoids, flooding and spotting, scab and lichen, bald white scalp sore, swelling toxin of welling abscess and sore, knocks and falls.	白族/布依族/哈尼族/基诺族/傈僳族/苗族/纳西族/佤族/彝族/藏族
TCMBANKHE006536/YEM-606	Rumex nepalensis|Rumex nepalensis Spreng.	尼泊尔羊蹄|尼泊尔酸模	土大黄	云南民族药物志：第三卷	See Rumex japonicus./See Rumex japonicus.	白族/布依族/哈尼族/基诺族/傈僳族/苗族/纳西族/佤族/彝族/藏族
TCMBANKHE007363/YEM-744/XU-850	Radix et Rhizoma Rhei|Rheum palmatum L.|Rheum palmatum	大黄; 生锦纹; 生军|掌叶大黄	掌叶大黄	云南民族药物志：第四卷|西藏昌都地区芒康县	To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge.; Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.; 1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect.	阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族
TCMBANKHE004455/YEM-744/XU-850	Rheum palmatum|Rheum palmatum L.	掌叶大黄	掌叶大黄	云南民族药物志：第四卷|西藏昌都地区芒康县	See Rheum officinale./See Rheum officinale.	阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族
TCMBANKHE004961/YNS-90/YEM-971	Cassia siamea|Cassia siamea Lam.	铁刀木	黑心树	云南药材标准：第三册|云南民族药物志：第五卷	清火解毒，杀虫止痒，除风止痛，通血消肿。用于皮肤疔疮疥癣、风疹、麻疹、水痘、湿疹、痱子及皮肤瘙痒；风湿病肢体关节肿胀疼痛；跌打损伤。	阿昌族/傣族/德昂族/景颇族/傈僳族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述