Compound Summary

  Compound Information

TCMBANKIN041860

药名:	hecogenin
别名:	hecogenin; EINECS 207-392-4; BSPBio_000660; ST5309385; 5alpha-Spirostan-12-one, 3beta-hydroxy-, (25R)- (8CI); Prestwick3_000730; 3-beta-Hydroxy-5-alpha-spirostan-12-one; 467-55-0; NSC 115921; BPBio1_000726; C08902; (22R,25R)-3beta-Hydroxy-5alpha-spirostan-12-one; Spirostan-12-one, 3-hydroxy-, (3beta,5alpha,25R)- (9CI)
分子式:	C27H42O4
Smiles:	C1([H])([H])C([H])([H])[C@](C([H])([H])[H])([C@@]([H])(C([H])([H])C(=O)[C@](C([H])([H])[H])([C@@]([H])([C@]([H])(C([H])([H])[H])[C@@]2(C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])O2)O3) [C@]3([H])C4([H])[H])[C@@]45[H])[C@@]5([H])C([H])([H])C6([H])[H])[C@]6([H])C([H])([H])[C@@]1([H])O[H]
成分:	HBIN028839
OB_score:	15.864632
CAS_id:	467-55-0
SymMap_id:	SMIT08757
TCMID_id:	9252
TCMSP_id:	MOL007291
PubChem_id:	91453

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE006589	Agave americana var. marginata [Syn. Agave americana var. variegata]	无刺番麻			To moisten lung, transform phlegm, suppress cough./Vacuity taxation cough, blood ejection, asthma.
TCMBANKHE004460	Cissampelos pareira	锡生藤			To relieve pain, stanch bleeding, engender flesh./Knocks and falls, asthma, heart disease.
TCMBANKHE004964	Agave east - one	剑麻
TCMBANKHE007143	Agave americana	番麻			To resolve toxin and draw out pus, kill worms, stanch bleeding./Sores with welling abscess and flat abscess, scab and lichen, pelvic inflammation, flooding.
TCMBANKHE007790	Agave angustifolia var. marginata	银边龙舌兰
TCMBANKHE005839	Asparagus setaceus [Syn. Asparagus plumosus]				To cool blood and resolve toxin, disinhibit urine and free strangury./Yin vacuity lung dryness, cough, hemoptysis, dribbling urination.
TCMBANKHE006597	Agave cantala	狭叶龙舌兰
TCMBANKHE007734	Fructus Tribuli	蒺藜			To subdue hyperactivity of the liver, to promote blood circulation, to dispel wind, to clear the eye of opacity, and to arrest itching./1. Antitussive, expectorant and antiasthmatic. 2. Its alcoholic infusion exerts hypotensive effect in anesthetized animals.
TCMBANKHE008778	Agave angustifolia	短叶龙舌兰
TCMBANKHE008256	Agave east - one	东一号剑麻
TCMBANKHE008257/YEM-229	Agave sisalana|Agave sisalana Perr ex Engelm.	剑麻	剑麻	云南民族药物志：第二卷		傣族/哈尼族/佤族
TCMBANKHE004965/YEM-229	Agave sisalana|Agave sisalana Perr ex Engelm.	剑麻;琼麻|剑麻	剑麻	云南民族药物志：第二卷	To cool blood and stanch bleeding, resolve toxin and disperse swelling./Tuberculosis and hemoptysis, spontaneous external bleeding, hematochezia, dysentery, welling abscess, hemorrhoids.	傣族/哈尼族/佤族
TCMBANKHE007939/YEM-89	Rhizoma Fagopyri Cymosi|Fagopyrum dibotrys (D.Don)Hara	金荞麦	金荞麦	云南民族药物志：第一卷	1. Its extractum and component flavanol promotes macrophage phagocytosis in the peritoneum of mouse.2. Flavanol is also an anti-inflammatory component. It promotes blood circulation and inhibits the agglutination of blood platelet./1. To clear heat and toxic material. For lung abscess, cough due to lung-heat, also for sorethroat and skin infection. 2. To promote blood circulation to eliminate blood stasis. For menorrhalgia due to blood stasis, postpartum abdominal pain due to blood	傣族/哈尼族/基诺族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000857	AHSA1	AHA1; C14orf3; hAha1; p38	activator of HSP90 ATPase activity 1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE002388	NR3C2	MCR; MLR; MR; NR3C2VIT	nuclear receptor subfamily 3 group C member 2
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor