Compound Summary

  Compound Information

TCMBANKIN042067

药名:	rhapontisterone
别名:	ZINC70455558; Punisterone; BG01179478; rhapontisterone; (1S,3AS,5AR,7R,8S,9AR,9BR,10R,11AR)-3A,7,8,10-TETRAHYDROXY-9A,11A-DIMETHYL-1-[(2R,3R,5S)-2,3,5-TRIHYDROXY-6-METHYLHEPTAN-2-YL]-1H,2H,3H,5AH,6H,7H,8H,9H,9BH,10H,11H-CYCLOPENTA[A]PHENANTHREN-5-ONE; 8240AH; 137476-71-2
分子式:	C27H44O8
Smiles:	[C@@]1([H])(O[H])C([H])([H])[C@](C([H])([H])[H])([C@@]([H])([C@]([H])(O[H])C([H])([H])[C@](C([H])([H])[H])([C@]([C@](O[H])(C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[C@@]([H])(C([H])(C([H])([H])[H])C([ H])([H])[H])O[H])([H])C([H])([H])C2([H])[H])[C@@]23O[H])C3=C([H])C4=O)[C@@]4([H])C([H])([H])[C@@]1([H])O[H]
成分:	HBIN042187
OB_score:	4.386539
CAS_id:	137476-71-2
SymMap_id:	SMIT04541;SMIT17450
TCMID_id:	18735
TCMSP_id:	MOL002264
PubChem_id:	11799446

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003426	Fructus Leonuri	茺蔚子			To activate blood circulation and regulate menstruation, to subdue hyperactivity of the liver, and to clear the eye of opacity./Treatment of menstrual disorders, amenorrhea, hysmenorrhea, inflammation of the eye with formation of corneal opacity, dizziness and headache.
TCMBANKHE006313	Radix et Rhizoma Rhei	大黄			To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.
TCMBANKHE006669	Radix Rhapontici	漏芦			To remove toxic heat for treating subcutaneous infections, to promote lactation, and to relieve muscular contracture./Mammary welling abscess, effusion of back from welling abscess and flat abscess, scrofula, galactostasis, damp impediment and hypertonicity.
TCMBANKHE007604	Herba Glechomae Longitubae	金钱草			To remove damp-heat, relieve dysuria, and to promote subsidence of swelling./Increasing biliary secretion.
TCMBANKHE007363/YEM-744/XU-850	Radix et Rhizoma Rhei|Rheum palmatum L.|Rheum palmatum	大黄; 生锦纹; 生军|掌叶大黄	掌叶大黄	云南民族药物志：第四卷|西藏昌都地区芒康县	To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge.; Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.; 1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect.	阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述