Compound Summary

  Compound Information

TCMBANKIN042452

药名:	piperlonguminine
别名:	(2E,4E)-5-(1,3-benzodioxol-5-yl)-N-isobutylpenta-2,4-dienamide; 5950-12-9; Piperlonguminine; (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide; (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-isobutyl-penta-2,4-dienamide; NSC125178; 5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide; 5-(1,3-benzodioxol-5-yl)-N-isobutylpenta-2,4-dienamide; 5-(1,3-benzodioxol-5-yl)-N-isobutyl-penta-2,4-dienamide
分子式:	C16H19NO3
Smiles:	CC(C)CNC(=O)C=CC=CC1=CC2=C(C=C1)OCO2
成分:	HBIN040086
OB_score:	30.711427
CAS_id:	5950-12-09
SymMap_id:	SMIT03953
TCMID_id:	17447
TCMSP_id:	MOL001559
PubChem_id:	5320621

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE008361		荜茇			Cold pain in stomach duct and abdomen, vomiting, diarrhea, headache, toothache, deep-source nasal congestion, coronary heart disease, angina pectoris.
TCMBANKHE008775	Rhizoma Dioscoreae	山药			To replenish the spleen and stomach, to promote fluid secretion and benefit the lung, and to strengthen the kidney and restrain seminal discharge.Rhizoma Dioscoreae (stir-fried with bran) To replenish the spleen and promote the stomach function./Reduced food intake due to spleen vacuity, incessant chronic diarrhea, cough and asthma due to lung vacuity, kidney vacuity and emission, vaginal discharge, frequent urination, vacuity heat and diabetes mellitus.
TCMBANKHE005228/YEM-235	Cortex Magnoliae officilis;Magnolia officinalis|Magnolia officinalis Rehd.et Wils.	厚朴	厚朴	云南民族药物志：第二卷	To eliminate damp and relieve distension;To dry damp and disperse phlegm, precipitate qi and eliminate fullness, lower blood pressure./1. Broad-spectrum antibacterial.2. Magnocurarine, one of the active components, can relaxstriated muscles.3. Its decoction stimulates the smooth muscles of intestines and bronchii in rabbits in vitro.4. Magnocuraine may also lower blood pressure and accelerate heart rate.5.Amebic dysentery, vomiting and diarrhea, food accumulation and qi stagnation, abdominal distention and constipation, phlegm-rheum cough asthma.	彝族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000242	SAA1	PIG4; SAA; SAA2; TP53I4	serum amyloid A1
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000764	TRPV1	VR1	transient receptor potential cation channel subfamily V member 1
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001467	LTA4H	-	leukotriene A4 hydrolase
TCMBANKGE001506	ADRA1B	ADRA1; ALPHA1BAR	adrenoceptor alpha 1B
TCMBANKGE001755	MAOB	-	monoamine oxidase B
TCMBANKGE003625	SLC6A4	5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT	solute carrier family 6 member 4
TCMBANKGE004136	SAA2	SAA; SAA1	serum amyloid A2
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE012155	SLC6A3	DAT; DAT1; PKDYS; PKDYS1	solute carrier family 6 member 3