Compound Summary


  Compound Information

药名:

loganin

别名:

SDCCGMLS-0066747.P001; KBio2_001983; Spectrum_001503; BSPBio_003350; methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[d]pyran-4-carboxylate; KBio2_004551; KBio1_001603; Loganin; C01433; KBioSS_001983; KBio2_007119; Spectrum2_001637; KBio3_002852; methyl (1S,4aS,6S,7R,7aS)-1-(beta-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate; SPBio_001733; Spectrum4_001914; (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-1,4a,5,6,7,7a-hexahydrocyclopenta[d]pyran-4-carboxylic acid methyl ester; Methyl (1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha))-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta(c)pyran-4-carboxylate; DivK1c_006659; Spectrum5_000628; CHEBI:15771; SpecPlus_000563; (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[d]pyran-4-carboxylic acid methyl ester; methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[d]pyran-4-carboxylate; 18524-94-2; EINECS 242-398-0; MEGxp0_000723; SPECTRUM1504066; ACon1_001749; Spectrum3_001875; ZINC03978792; 1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid methyl ester; KBioGR_002535; LMPR01020102

分子式:

C18H28O10

Smiles:

[C@]12([H])[C@@]([H])([C@@]([H])(C([H])([H])[H])[C@@]([H])(O[H])C1([H])[H])[C@]([H])(O[C@]([H])(O[C@@]3(C([H])([H])O[H])C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(O[H])[C@@]3([H])O[H])OC([H])=C2C(OC([H]) ([H])[H])=O

成分:

HBIN033476

SymMap_id:

SMIT01491;SMIT04056

TCMID_id:

12944

TCMSP_id:

MOL001680

PubChem_id:

87691


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000999 红芪 to promote the drainage of pus and the growth of new tissue.
TCMBANKHE001015 Herba Serissae 白马骨
TCMBANKHE001763 Ophiorrhiza liukiuensis 琉球蛇根草
TCMBANKHE001868 Lonicera quinquelocularis
TCMBANKHE002046 金果揽 See Tinospora sagittata .
TCMBANKHE002292 橘红
TCMBANKHE003723 Flos Lonicerae 金银花 To remove toxic heat and dispel wind-heat./Infection of upper respiratory tract, tonsillitis, acute laryngitis, skin suppurations, welling abscess, viral conjunctivitis, influenza, pneumonia, mastitis, acute appendicitis, warm disease fever, heat toxin blood dysentery, swollen welling abscess and clove sores, throat impediment.
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE003782 Fructus Corni 山茱萸 To replenish the liver and kidney, restrain seminal discharge and relieve collapse./Dizziness and tinnitus, aching in lumbus and knees, impotence and emission, enuresis and frequent urination, flooding and spotting with vaginal discharge, vacuity and profuse sweating, vacuity desertion due to great sweating, diabetes mellitus due to internal heat, dysmenorrhea.
TCMBANKHE003857 Semen Strychni 马钱子 To promote the flow of qi and blood in the collaterals, relieve pain, and promote the subsidence of swelling./Hemiplegia, numbness and paralysis, muscle weakness, impotence, hypertrophic spinitis, chronic anemia, wind-damp intractable impediment, sequel of poliomyelitis, rheumatoid arthritis, knocks and falls, swelling pain of welling abscess and flat abscess.
TCMBANKHE004053 Sinoadina racemosa [Syn. Adina racemosa ] 鸡子木
TCMBANKHE006088 Patrinia scabiosaefolia 黄花败酱 See Patrinia villosa ./See Patrinia villosa.
TCMBANKHE004431 Semen Strychni;Strychnos dolichothyrsa;Semen Cumini Cymni;Strychnos mittschelichii 马钱子 To promote the flow of qi and blood in the collaterals, relieve pain, and promote the subsidence of swelling./Hemiplegia, numbness and paralysis, muscle weakness, impotence, hypertrophic spinitis, chronic anemia, wind-damp intractable impediment, sequel of poliomyelitis, rheumatoid arthritis, knocks and falls, swelling pain of welling abscess and flat abscess.
TCMBANKHE007156 Herba Patriniae 败酱草 1. To eliminate heat and toxic material, relieve abscess and promote pus drainage. 2. To remove blood stasis and alleviate pain/1. Two active components, patrinene and isopatrinene, possess sedative effect. 2. To promote regeneration of hepatic cells and portal circulation, protect hepatic cells from degernation and improve hepatic function.
TCMBANKHE005444 白鲜皮 To clear heat and dry damp, dispel wind and relieve itch, resolve toxin./1. Inhibiting the growth of pathogenic fungi. 2. Its infusion lowers vaccine-induced fever in rabbits. 3. Dictamnine, one of its active components, increase the myocardial tone of frogs. Dermatitis, psoriasis, icterohepatitis, damp-heat sore and papules, profuse pus, yellow-water sore, damp ulceration on skin, itchy skin, damp-heat jaundice, damp-heat impediment.
TCMBANKHE008234 Patrinia villosa 败酱 To clear heat and resolve toxin, expel pus and break stasis./Intestinal welling abscess, dysentery, red and white vaginal discharge, postpartum blood stasis abdominal pain, red eyes with gall, swollen welling abscess, scab and lichen.
TCMBANKHE007541 Menyanthes trifoliata 睡菜 To fortify spleen and disperse food, nourish heart and quiet spirit, clear heat and disinhibit urine./Gastritis, indigestion, palpitation and insomnia, damp-heat jaundice, cholecystitis, edema, inhibited urination, inhibited voidings of reddish urine.
TCMBANKHE007954 Flos Rhododendri Mollis 闹羊花 To relieve rheumatic conditions, and to eliminate blood stasis and alleviate pain./Tachycardia, palpitation, hypertension, wind-damp impediment pain, knocks and falls, intractable lichen.
TCMBANKHE006988 Strychnos ignatii 吕宋果 To resolve toxin, disperse swelling, kill worms, relieve pain./Stomachache, diarrhea, dysentery, malaria, worm accumulation, bleeding due to external injury, centipede bite.
TCMBANKHE007889 杜仲叶 Lumbar and back pain, limp aching inability of legs and knees, hypertension.
TCMBANKHE004162/YEM-17 Catharanthus roseus|Catharanthus roseus (L.) G.Don 长春花 长春花 云南民族药物志:第一卷 To resolve toxin, clear heat and calm liver, anticancer./Hypertension, swelling toxin of welling abscess and sore, scalds.
TCMBANKHE004112/YEM-886 Fructus Rosae laevigatae|Rosa laevigata Michx. 金樱子 金樱子 云南民族药物志:第五卷 1. To control the essence; 2. To astringe the intestines and stop diarrhea; 3. To decrease urination/Emission, enuresis and frequent urination, flooding and spotting with vaginal discharge, chronic diarrhea and dysentery. 布依族/回族/苗族/水族/瑶族/彝族/藏族/壮族
TCMBANKHE005867/YEM-91 Lonicera japonica|Lonicera japonica Thunb. 忍冬藤|金银花 金银花 云南民族药物志:第一卷 To clear heat and resolve toxin, free network vessels./Warm disease fever, swelling toxin of sore and welling abscess, heat toxin blood dysentery, wind-damp-heat impediment. 阿昌族/白族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/纳西族/佤族/瑶族/彝族/壮族
TCMBANKHE007630/YEM-983 Dipsacus asperoides|Dipsacus asperoides C.Y.Cheng et T.M.Ai 川续断 续断 云南民族药物志:第五卷 To supplement liver and kidney, strengthen sinews and bones, joint bones, check flooding and spotting./Limp aching lumbus and knees, wind-damp impediment pain, flooding and spotting, profuse menstruation, fetal bleeding, knocks and falls. 白族/布依族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/苗族/纳西族/彝族
TCMBANKHE006587/YEM-983 Radix Dipsaci|Dipsacus asperoides C.Y.Cheng et T.M.Ai 续断|川续断 续断 云南民族药物志:第五卷 For tonifying yang/See Dipsacus asperoides. 白族/布依族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/苗族/纳西族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2