Compound Summary

  Compound Information

TCMBANKIN042961

药名:	silybin b
别名:	Silybin B; Silybum marianum; I14-4850; (2R,3R)-3,5,7-trihydroxy-2-((2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one; (2S,3S)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-[(2R,3R)-3,5,7-trihydroxy-4-oxobenzopyran-2-yl]benzodioxin; Milk thistle [NF]; CCRIS 7096; LS41186; (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxy-phenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]chroman-4-one; 2717AH; Milk Thistle (Silybum marianum) Extract or Powder; 2-(2,3-Dihydro-2-(4-Hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-1,4-benzodioxin-6-yl)-2,3-dihydro-3,5,7-trihydroxy-4h-1-benzopyran-4- one; SCHEMBL751461; PRX-321; UNII-4RKY41TBTF component SEBFKMXJBCUCAI-WAABAYLZSA-N; (2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-hydroxymethyl-2,3-dihydrobenzo[1,4]dioxin-6-yl]-4-chromanone; (2R,3R)-3,5,7-TRIHYDROXY-2-[(2S,3S)-3-(4-HYDROXY-3-METHOXYPHENYL)-2-(HYDROXYMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL]-2,3-DIHYDRO-1-BENZOPYRAN-4-ONE; AC1LU7MH; ZINC1530850; Milk Thistle (Silybum marianum) Extract or Powder [seed]; 853OHH1429; (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one; CHEMBL592675; (2r,3r)-2-[(2s,3s)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4h-1-benzopyran-4-one; Flavobion; DTXSID30858697; MolPort-039-139-345; Wild Artichoke; Legalon 70; Milk thistle; U946SH95EE; Legalon; UNII-853OHH1429; Silybin B, analytical standard; J-505458; D0C5VQ; AKOS015912848; UNII-U946SH95EE; 142797-34-0; SILYMARIN; SEBFKMXJBCUCAI-WAABAYLZSA-N; BDBM50088491; (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one; Silymarin + Melatonin
分子式:	C25H22O10
Smiles:	COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
成分:	HBIN044035
SymMap_id:	SMIT17713
TCMID_id:	19880
PubChem_id:	1548994

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE006366	Radix Moghaniae Philippinensis	千斤拔
TCMBANKHE006357		水飞蓟			Acute hepatitis, chronic hepatitis, cirrhosis, fatty liver, gallstones, cholangitis.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000199	ICAM1	BB2; CD54; P3.58	intercellular adhesion molecule 1
TCMBANKGE000204	CXCL8	GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8	C-X-C motif chemokine ligand 8
TCMBANKGE000298	SOD1	ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer	superoxide dismutase 1
TCMBANKGE000315	IL4	BCGF-1; BCGF1; BSF-1; BSF1; IL-4	interleukin 4
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000697	APAF1	APAF-1; CED4	apoptotic peptidase activating factor 1
TCMBANKGE000788	SELE	CD62E; ELAM; ELAM1; ESEL; LECAM2	selectin E
TCMBANKGE000921	CCNB1	CCNB	cyclin B1
TCMBANKGE001008	CYP3A4	CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1	cytochrome P450 family 3 subfamily A member 4
TCMBANKGE001013	BIRC5	API4; EPR-1	baculoviral IAP repeat containing 5
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001069	MPO	-	myeloperoxidase
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001161	IL2	IL-2; TCGF; lymphokine	interleukin 2
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001169	BCL2L1	BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52	BCL2 like 1
TCMBANKGE001176	CAT	-	catalase
TCMBANKGE001182	SIRT1	SIR2; SIR2L1; SIR2alpha	sirtuin 1
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE003210	POLD1	CDC2; CRCS10; MDPL; POLD	DNA polymerase delta 1, catalytic subunit
TCMBANKGE004731	ABCB5	ABCB5alpha; ABCB5beta; EST422562	ATP binding cassette subfamily B member 5
TCMBANKGE006248	FCER2	BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF	Fc fragment of IgE receptor II
TCMBANKGE006368	UGT1A1	BILIQTL1; GNT1; HUG-BR1; UDPGT; UDPGT 1-1; UGT1; UGT1A	UDP glucuronosyltransferase family 1 member A1
TCMBANKGE008786	CRAT	CAT; CAT1; NBIA8	carnitine O-acetyltransferase
TCMBANKGE009361	GPT	AAT1; ALT1; GPT1	glutamic--pyruvic transaminase
TCMBANKGE012906	PCDHAC2	PCDH-ALPHA-C2	protocadherin alpha subfamily C, 2
TCMBANKGE012983	CSNK1A1	CK1; CK1a; CKIa; HEL-S-77p; HLCDGP1; PRO2975	casein kinase 1 alpha 1
TCMBANKGE013356	IL4R	CD124; IL-4RA; IL4RA	interleukin 4 receptor