Compound Summary


  Compound Information

药名:

aucubin

别名:

AIDS031379; 1,4a,5,7a-Tetrahydro-5-hydroxy-7-hydroxymethylcyclopenta(c)pyran-1-yl-beta-D-glucopyranoside; MEGxp0_001729; 479-98-1; AIDS-031379; Aucubin; NSC 407293; 55561_FLUKA; LMPR01020107; AKOS015965329; ZINC04098334; (1S-(1alpha,4aalpha,5alpha,7aalpha))-1,4a,5,7a-Tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta(c)pyran-1-yl-beta-D-glucopyranoside; C09771; AC-20186; ACon1_002452; (2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; EINECS 207-540-8; (2S,3R,4S,5S,6R)-2-((1S,4aR,5R,7aS)-5-Hydroxy-7-hydroxymethyl-1,4a,5,7a-tetrahydro-cyclopenta[c]pyran-1-yloxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol; (2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-hydroxy-7-methylol-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-methylol-tetrahydropyran-3,4,5-triol; (2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol

分子式:

C15H22O10

Smiles:

[C@@]12([H])[C@@]([H])(C(C([H])([H])O[H])=C([H])[C@@]1([H])O[H])[C@]([H])(OO[C@@]3([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]3([H])O[H])OC([H])=C2[H]

成分:

HBIN017343

CAS_id:

479-98-1

SymMap_id:

SMIT01287;SMIT04994

TCMID_id:

2004

TCMSP_id:

MOL002813;MOL003735

PubChem_id:

91458


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000255 车前与车前草
TCMBANKHE000348 Scrophularia lepidota
TCMBANKHE001767 羊耳朵叶
TCMBANKHE002688 Semen armeniacae amarum 苦杏仁 To relieve cough and asthma, and to relax bowels./Treatment of cough and asthma accompanied by stuffiness in the chest and profuse expectoration, constipation due to deficiency of blood and fluid.
TCMBANKHE003063 Herba Plantaginis 车前草 To remove heat and to induce diureses, to promote expectoration, to reduce heat in blood and to counteract toxicity./Treatment of edema with oliguria, urinary infection with difficult painful urination, diarrhea caused by summer-damp, cough caused by phlegm-heat, spitting of blood, epistaxis, carbuncles and sores.
TCMBANKHE003282 檰芽
TCMBANKHE003718 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE003752 Radix Salviae liguliobae 丹参 To remove blood stasis and relieve pain, to promote the flow of blood and stimulate menstrual discharge, and to ease the mind./Angina pectoris, cerebral atherosclerosis, diffusive intravascular clotting, thrombophlebitis, hepatitis, acute surgical infection, mastitis, erysipelas, otitis media, tonsillitis, bone marrow infection, menstrual disorder, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, pain in heart and abdomen, concretion conglomeration accumulation and gathering, heat impediment swelling and pain, knocks and falls, heat entering construction-blood, vexation and agitation, insomnia and vexation, swelling toxin of welling abscess and sore, zoster, neurodermatitis, psoriasis.
TCMBANKHE003767 Odontites serotina 齿叶草 To clear heat and dry damp, cool blood and relieve pain./Febrile infectious diseases, depressed liver-gallbladder heat, pain of blood stasis.
TCMBANKHE003827 Picrorhiza scrophulariiflora 西藏胡黄连 See Picrorhiza kurrooa ./See Picrorhiza kurrooa.
TCMBANKHE003840 Veronica persica 阿拉伯婆婆纳 To dispel wind and eliminate damp, strengthen lumbus, interrupt malaria./Wind-damp impediment pain, kidney vacuity lumbago, enduring malaria.
TCMBANKHE004259 Plantago major 大车前 See Plantago asiatica./See Plantago asiatica.
TCMBANKHE004502 Aucuba japonica 东瀛珊瑚木
TCMBANKHE008565 Rehmannia glutinosa [Syn. Rehmannia glutinosa f. huechingensis] 干地黄 To enrich yin and clear heat, cool blood and supplement blood, lower blood sugar levels./Diabetes mellitus, dermatitis, rheumatism, diphtheria, acute tonsillitis, febrile diseases with vexation and thirst, steaming bone taxation fever, warm disease macular eruption, blood ejection due to blood heat, spontaneous external bleeding due to blood heat, flooding and spotting due to blood heat, hematuria due to blood heat, hematochezia due to blood heat, anemia with yellow complexion, palpitation and dizziness, blood depletion and amenorrhea.
TCMBANKHE004661 Euphrasia officinalis 小米草 To clear heat and resolve toxin, disinhibit urine./Febrile diseases thirst, headache, lung heat cough, swelling pain in throat, heat strangury, inhibited urination, mouth sore, swollen welling abscess.
TCMBANKHE004992 Plantago lanceolata 长叶车前
TCMBANKHE005171 Aucuba chinensis ssp. omeiensis 天脚板 To clear heat and resolve toxin, disperse swelling and relieve pain./Swelling toxin of welling abscess and flat abscess, scratch, knocks and falls, burns and scalds, hemorrhoids, frostbite.
TCMBANKHE007088 Veronica arvensis 直立婆婆纳 To clear heat, interrupt malaria./Malaria.
TCMBANKHE007155 Radix Scrophulariae 玄参; 元参 To reduce heat from blood, to nourish yin, to quench fire, and to counteract toxicity. Treatment of febrile diseases with impairment of yin manifested by deep red tongue and dire thirst, or with eruptions, constipation due to impairment of body fluid, phthisis with cough, conjunctivitis, sore throat, scrofula, diphtheria, boils and sores./Heat entering construction-blood, generalized fever, vexation and thirst, crimson tongue, macular eruption, steaming bone taxation cough, vacuity vexation and insomnia, fluid damage and constipation, dry eyes with clouded flowery vision, swelling pain in throat, scrofula with phlegm node, sore toxin of welling abscess and flat abscess. 1. Its alcoholic extract and its component methoxycinnamic acid can lower the typhoid vaccine-induced fever in rabbits.2. Its water or alcoholic infusion and decoction exert a mild hypotensive effect on anesthetized animals3. Lowering the level of blood sugar.4. Its infusion inhibits the growth of some dermatomyces.
TCMBANKHE005363 Semen Plantaginis 车前子 To remove heat, to cause diuresis and eliminate damp, to relieve dysuria, to clear the eye, and to promote expectoration./1. Diuretic. 2. Expectorant and antitussive.
TCMBANKHE005404 Plantago asiatica 车前 To clear heat and disinhibit urine, cool blood, resolve toxin./Heat bind in bladder, inhibited urination [=dysuria], strangury-turbidity and vaginal discharge, summerheat-damp diarrhea, bloody urine (hematuria), spontaneous external bleeding, swelling toxin of welling abscess and sore.
TCMBANKHE008310 Cortex Eucommiae 杜仲 To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy.
TCMBANKHE005749 Veronica serpyllifolia 小婆婆纳 To quicken blood and dissipate stasis, stanch bleeding, resolve toxin./Knocks and falls, menstrual disorder, bleeding due to external injury, mouth sore, burns and scalds.
TCMBANKHE005793 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE005874 玳玳花 Oppression in chest due to glomus, distending pain in stomach duct and abdomen, vomiting, reduced food intake.
TCMBANKHE005940 Vitex rotundifolia [Syn. Vitex trifollia var. simplicifolia ] 单叶蔓荆
TCMBANKHE008532 Radix Rehmanniae Preparata 熟地黄 To nourish n and replenish blood, reinforce the essence of life and marrow./Blood vacuity with yellow complexion, dizziness and palpitation, menstrual disorder [=menoxenia], incessant flooding and spotting, liver-kidney yin depletion, tidal fever with night sweat, impotence and emission, sterility and infertility, limp aching lumbus and knees, tinnitus and deafness, dizzy head and vision, premature graying in beard and hair, diabetes mellitus, constipation, kidney vacuity hasty asthma.
TCMBANKHE006991 胡黄连 Steaming bone tidal fever due to yin vacuity, night sweating, child gan accumulation, indigestion, abdominal distention and emaciation, dysentery, fever, gastrointestinal damp-heat diarrhea, hemorrhoids.
TCMBANKHE007806 Plantago depressa 平车前 See Plantago asiatica./See Plantago asiatica.
TCMBANKHE007889 杜仲叶 Lumbar and back pain, limp aching inability of legs and knees, hypertension.
TCMBANKHE006141/XU-16 Clerodendrum thomsonae|Clerodendrum 龙吐珠|大青属 云南省昆明市禄劝小河线板桥村 To resolve toxin./Knocks and falls, chronic tympanitis.
TCMBANKHE007867/XU-103 Flos Buddlejae|Buddleja officinalis 密蒙花 云南省昆明市盘龙区 To remove heat, replenish the liver and clear the eye of corneal opacity./Red eyes with gall, delacrimation and photophobia, liver vacuity dim vision, dim vision, malaria.
TCMBANKHE006292/YNS-298/YEM-187/XU-40/XU-99 Verbascum thapsus|Verbascum thapsus L|Verbascum thapsus L. 毛蕊花 一柱香 云南药材标准:第六册|云南民族药物志:第一卷|云南省昆明市盘龙区 清热解毒,活血止血。用于肺热咳嗽,湿热痹痛,肠痈,疮毒,湿疹,跌打扭伤,创伤出血。|To clear heat and resolve toxin, stanch bleeding and dissipate stasis./Pneumonia, chronic appendicitis, sore toxin, sprain from knocks and falls, bleeding due to external injury. 白族/傈僳族/纳西族/彝族/藏族
TCMBANKHE005361/YEM-268/XU-394 Catalpa ovata|Catalpa ovata Don. 梓木|梓 梓木 云南民族药物志:第二卷|云南省保山市腾冲市明光镇中塘村 To promote vomiting, relieve pain./Pain wind in limbs, cholera. 傈僳族/水族
TCMBANKHE004801/YEM-339 Herba Verbae|Verbena officinalis L. 马鞭草 马鞭草 云南民族药物志:第二卷 To promote the flow of blood and to relieve blood stasis, to stop malarial attacks, to counteract toxicity, and to cause diuresis./Malaria, amenorrhea and dysmenorrhea, throat impediment, edema, heat strangury, diphtheria, bilharziosis, dysentery, concretion conglomeration accumulation and gathering. 白族/布朗族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/纳西族/普米族/佤族/彝族/藏族/壮族
TCMBANKHE008167/YEM-39/XU-672 Cortex Eucommiae|Eucommia ulmoides Oliv.|Eucommia ulmoides 杜仲 杜仲 云南民族药物志:第一卷|贵州省岑巩县平庄镇师兆村 To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE008309/YEM-39/XU-672 Cortex Eucommiae|Eucommia ulmoides Oliv.|Eucommia ulmoides 川杜仲|杜仲 杜仲 云南民族药物志:第一卷|贵州省岑巩县平庄镇师兆村 Treatment of deficiency condition of the kidney marked by lumbago and lack of strength, threatened abortion, hypertension./1. Hypotensive 2. Promoting phagocytosis of mononuclear phagocytes3. Sedative and diuretic. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE004071/YEM-649 Bulbus Allii|Allium sativum L. 大蒜 大蒜 云南民族药物志:第四卷 Toxication reduction, anthelmintic, dampness removal, and itching control/Cold pain in stomach duct and abdomen, diarrhea, dysentery, bacillary dysentery, amebic dysentery, tuberculosis, epidemic encephalitis, cholera, trichomoniasis, laryngeal carcinoma, pertussis, throat impediment, dry cough, common cold, malaria, edema, swelling toxin of welling abscess and boil, intestinal welling abscess, lichen sore, snake or insect bites, ancylostomiasis, oxyuria disease, taenia infection, vaginal discharge and pudendal itch, clavus. 阿昌族/布依族/傣族/德昂族/回族/哈尼族/基诺族/景颇族/傈僳族/水族/佤族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001098 NFKBIA EDAID2; IKBA; MAD-3; NFKBI NFKB inhibitor alpha
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001132 BAX BCL2L4 BCL2 associated X, apoptosis regulator
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1