Compound Summary


  Compound Information

药名:

18alpha-glycyrrhetinic acid

别名:

J-008025; A-GLYCYRRHETINIC ACID; 1449-05-4; 18-; CG0020; 18 alpha-glycyrrhetinic acid; SMP1_000143

分子式:

C30H46O4

Smiles:

CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C

成分:

HBIN002087

SymMap_id:

SMIT18313

TCMID_id:

23166

PubChem_id:

16219451


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000312 Radix Glycyrrhizae Preparata 炙甘草 Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE000541 甘草头
TCMBANKHE000702 Radix Glycyrrhizae Praeparata 炙草 Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE001384 Radix Glycyrrhizae uralensis 甘草稍
TCMBANKHE003349 甘草节
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000313 JUN AP-1; AP1; c-Jun; cJUN; p39 Jun proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000898 MYC MRTL; MYCC; bHLHe39; c-Myc MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001045 CCND1 BCL1; D11S287E; PRAD1; U21B31 cyclin D1
TCMBANKGE001170 CDK4 CMM3; PSK-J3 cyclin dependent kinase 4
TCMBANKGE001197 FOS AP-1; C-FOS; p55 Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE010213 HERC5 CEB1; CEBP1 HECT and RLD domain containing E3 ubiquitin protein ligase 5