Compound Summary

  Compound Information

TCMBANKIN044371

化合物待补充

药名:	Noroxyhydrastinine
别名:	7,8-dihydro[1,3]dioxolo[4,5-g]isoquinolin-5(6H)-one; 7,8-Dihydro[1,3]dioxolo[4,5-g]isoquinolin-5(6H)-one; CTK4E7692; VSOJKDUWYQCWFM-UHFFFAOYSA-; noroxyhydrastinine; 6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydroisoquinoline; 7,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquinolin-5-one; NSC 201020; NSC-201020; InChI=1/C10H9NO3/c12-10-7-4-9-8(13-5-14-9)3-6(7)1-2-11-10/h3-4H,1-2,5H2,(H,11,12); 7,8-DIHYDRO-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5(6H)-ONE; AC1Q6NHB; AK396339; 1,5-g]isoquinolin-5(6H)-one, 7,8-dihydro-; MolPort-000-881-842; CHEMBL449731; AC1L3H11; NSC201020; 1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one,7,8-dihydro-; ZINC1735195; MLS000546669; 2H,6H,7H,8H-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5-ONE; HMS2346J04; 21796-14-5; 7,8-Dihydro-1,3-dioxolo[4,5-g]isoquinolin-5(6H)-one; DTXSID30176207; 7,8-Dihydro[1,3]dioxolo[4,5-g]isoquinolin-5(6H)-one #; SCHEMBL564339; 1,3-Dioxolo(4,5-g)isoquinolin-5(6H)-one, 7,8-dihydro- (8CI)(9CI); ACM21796145; 6,7-methylenedioxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline; VSOJKDUWYQCWFM-UHFFFAOYSA-N; FCH843447; NP-006295; SMR000113841; 1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one, 7,8-dihydro-; NCGC00247079-01; AKOS000277625
成分:	HBIN037372
OB_score:	38.888393
CAS_id:	21796-14-5
SymMap_id:	SMIT05062;SMIT16923
TCMID_id:	15778
TCMSP_id:	MOL002900
PubChem_id:	89047

---

   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002436	Thalictrum minus var. adiantifolium
TCMBANKHE002730		橘络
TCMBANKHE002762	Radix et Rhizoma Thalictri	马尾莲			Influenza, fever in children, common cold with fever, measles papules, malaria, damp-heat diarrhea dysentery, jaundice, red eyes with gall.
TCMBANKHE003194	Thalictrum rugosum	走稳唐松草
TCMBANKHE003748	Rhizoma Coptidis	黄连			To remove damp-heat, quench fire and counteract toxicity./Febrile infectious diseases, dysentery, blood ejection, spontaneous external bleeding, diphtheria, infection of upper respiratory tract, scarlatina, typhoid fever, acute conjunctivitis, otitis media, acute surgical infection, septicemia, hepatitis, trichomoniasis, eruptive dermatitis, hypertension, vexation and agitation, clouded spirit with delirious speech, damp-heat glomus in chest, damp-heat diarrhea dysentery, insomnia and vexation due to effulgent fire, stomach heat vomiting, swift digestion with rapid hungering, red eyes with pain due to liver fire, heat toxin sores, clove sore running yellow, gum swelling and pain, mouth sore, tongue sores, genital swelling, bleeding from hemorrhoids, eczema, scalds.
TCMBANKHE004522	Rhizoma Corydalis	延胡索			1. To invigorate blood and promote qi circulation; 2. To stop pain/Chest and rib-side pain, pain in stomach duct and abdomen, neuralgia, gastrointestinal spasm, amenorrhea and dysmenorrhea, postpartum stasis stagnation abdominal pain, painful swelling from knocks and falls.
TCMBANKHE004731	Thalictrum alpinum	高山唐松草			To clear heat and drain fire, resolve toxin./Headache and red eyes, diarrhea, dysentery, sores.
TCMBANKHE008108	Thalictrum rugosum	绉纹唐松草
TCMBANKHE004238/YEM-1014	Phellodendron amurense;Cortex Phellodendri|Phellodendron chinense Schneid var.glabriusculum Schneid.	黄柏|秃叶黄蘗	广西黄柏	云南民族药物志：第五卷	1. To clear heat and dry dampness; 2. To reduce fire and release toxins/Damp-heat dysentery, tuberculosis, epidemic meningitis, acute conjunctivitis, trachoma, fever, abdominal pain, diarrhea, suppurative hematochezia, tenesmus, jaundice, yellow thick foul leukorrhagia, swelling pain in knees and feet, urinary tract infection, boil, sore, ulcer, eczema, mouth sore, hemorrhoids, burns, scalds, exuberance of fire with tidal fever, tidal fever with night sweat, emission.	瑶族/壮族

---

   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

---

   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001194	ADRA2A	ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32	adrenoceptor alpha 2A
TCMBANKGE001755	MAOB	-	monoamine oxidase B
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1