Compound Summary


  Compound Information

药名:

questin

别名:

questin-2-olate; 1,6-dihydroxy-8-methoxy-3-methylanthracene-9,10-dione; 3774-64-9; 1,6-dihydroxy-8-methoxy-3-methyl-9,10-anthraquinone; emodin-8-methyl ether; 5-hydroxy-4-methoxy-7-methyl-9,10-dioxo-9,10-dihydroanthracen-2-olate; 9,10-Anthracenedione, 1,6-dihydroxy-8-methoxy-3-methyl-; CHEBI:57676; 1,6-dihydroxy-3-methyl-8-(methyloxy)anthracene-9,10-dione; 3,8-dihydroxy-1-methoxy-6-methylanthracene-9,10-dione; 1,6-dihydroxy-8-methoxy-3-methyl-anthracene-9,10-dione; CHEBI:16200; C01448; Questin

分子式:

C16H12O5

Smiles:

c1([H])c(O[H])c(C(=O)c(c(OC([H])([H])[H])c([H])c(O[H])c2[H])c2C3=O)c3c([H])c1C([H])([H])[H]

成分:

HBIN041737

SymMap_id:

SMIT01590;SMIT08096

TCMID_id:

18401

TCMSP_id:

MOL006488

PubChem_id:

160717


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001170 猕猴桃根
TCMBANKHE003373 Exocarpium Citri grandis 化橘红 To dispel cold, eliminate damp and phlegm, and arrest emesis or nausea./Treatment of cough, itching of the throat and profuse expectoration in colds, nausea, vomiting and epigastric distension caused by improper diet or excessive drinking.
TCMBANKHE003822 Rumex patientia 牛西西 To clear heat and resolve toxin, stanch bleeding and disperse swelling, free stool and kill worms./Blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, red and white vaginal discharge, purpura, dysentery, hepatitis, constipation, inhibited urination, swelling toxin of welling abscess and sore, scab and lichen, knocks and falls, burns and scalds.
TCMBANKHE004026 Polygonum multiflorum;Caulis Polygoni Multiflori 夜交藤;首乌藤 To nourish heart and quiet spirit, dispel wind and free network vessels.;Treatment of insomnia, dream-disturbed sleep, general aching in blood deficiency, rheumatic arthralgia, external use for itching./Insomnia, frequent dreaming, anemia and generalized pain, muscle numbness, wind-damp impediment pain, wind papule itching.;1. Decreasing the level of blood lipids and inhibiting the formation of atherosclerosis.2. Oral admintration of its decoction increases the level of blood sugar in rabbits.
TCMBANKHE004160 Semen Cassiae;Semen Sene 决明子 To remove heat from the liver, to improve eyesight, and to relax bowels./See Cassia obtusifolia.
TCMBANKHE004697 Radix Kansui 甘遂 To cause drastic purgation and expel the retained water./Edema, ascites, flowing rheum in chest, concretion conglomeration accumulation and gathering, epilepsy, cough and asthma, urinar y and fecal stoppage.
TCMBANKHE006281 Polygonum multiflorum 夜交藤 To nourish heart and quiet spirit, dispel wind and free network vessels./Insomnia, frequent dreaming, anemia and generalized pain, muscle numbness, wind-damp impediment pain, wind papule itching.
TCMBANKHE008555 Polygonum multiflorum 何首乌 To lower cholesterol, enrich yin and nourish blood, moisten intestines and free stool, interrupt malaria, dispel wind, resolve toxin./Backache, neurasthenia, hyperlipemia, neurosis, insomnia, dizziness due to anemia, palpitation, limp aching lumbus and knees due to liver kidney yin vacuity, premature graying in beard and hair, tinnitus, emission, intestinal dry and constipation, enduring malaria, wind papule itching, sore and welling abscess, scrofula, hemorrhoids.
TCMBANKHE006991 胡黄连 Steaming bone tidal fever due to yin vacuity, night sweating, child gan accumulation, indigestion, abdominal distention and emaciation, dysentery, fever, gastrointestinal damp-heat diarrhea, hemorrhoids.
TCMBANKHE005418/YNS-102 Rhizoma Polygoni cuspidati|Polygonum cuspidatum Sieb.et Zucc. 虎杖 虎杖叶 云南药材标准:第一册 平肝潜阳,祛痰息风。用于肝阳上亢,血压偏高,头晕头昏|To dispel wind and damp, to eliminate blood stasis and alleviate pain, to relieve cough, and to resolve phlegm./Hyperlipemia, impediment pain in joints, damp-heat jaundice, toxic jaundice, child jaundice, amenorrhea, hepatitis, appendicitis, candida vaginitis, concretion and conglomeration, cough with profuse phlegm, burns and scalds, knocks and falls, swelling toxin of welling abscess and sore.
TCMBANKHE005316/YNS-201/YEM-138/XU-16/XU-159 Clerodendron serratum|Clerodendrum serratum|Clerodendrum serratum (L.) Moon 三台红花|三对节 三对节根|三台红花 云南药材标准:第三册|云南民族药物志:第一卷|云南省普洱市江城县国庆乡和平村弄扎河小组 清热解毒,截疟,接骨,祛风除湿。用于扁桃体炎,咽喉炎,风湿骨痛,疟疾,肝炎;外用治痈疖肿毒,骨折,跌打损伤。|To clear heat and disinhibit damp, dissipate stasis and relieve pain, resolve toxin and disperse swelling, interrupt malaria./Damp-heat dysentery, strangury syndrome, wind-damp-heat impediment, blood stasis and dysmenorrhea, knocks and falls, swelling pain in throat, swelling toxin of welling abscess and flat abscess, urticaria, malaria. 傣族/基诺族/佤族
TCMBANKHE006959/YNS-135/YEM-14 Semen Cassiae;Semen Sene|Cassia tora Linn.|Cassia tora L. 决明子;草决明|决明 决明根|草决明 云南药材标准:第三册|云南民族药物志:第一卷 安神补脑,清肝明目,理气止痛。主治失眠多梦,入睡易惊,腹内痉挛剧痛,腹部包块,黄疸,疟疾。|To remove heat from the liver, to improve eyesight, and to relax bowels.Treatment of inflammation in the eye with pain, photophobia and lacrimination, headache, dizziness, blurred vision and constipation./See Cassia obtusifolia.1. Oral adminstration of the hearbal powder can inhibit the rising of serum cholesterol and formation of atherosclerosis in rabbits.2. Its tincture and infusion can inhibit the myocardium of toad in vitro, and contract th eblood vessels of lower limbs.3. Its infusion can lower the blood pressure in dogs, cats and rabbits.4. Chrysophanol, one of the active components, is a laxative.5. Bacteriostatic. 傣族/基诺族/拉祜族/傈僳族/苗族/佤族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000474 NCOA1 F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 nuclear receptor coactivator 1
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1