Compound Summary


  Compound Information

药名:

7alpha,21S,25-Trihydroxy-3beta-acetoxy-21S,23R-epoxy-9(11)-en-dammarane

别名:

[(3S,8S,10S)-7-hydroxy-17-[(2S,5R)-2-hydroxy-5-(2-hydroxy-2-methylpropyl)oxolan-3-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,12,13,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate; AC1NT14F; 7α,21s,25-trihydroxy-3β-acetoxy-21s,23r-epoxy-9(11)-en-dammarane; 7alpha,21s,25-trihydroxy-3beta-acetoxy-21s,23r-epoxy-9(11)-en-dammarane

分子式:

C32H52O6

Smiles:

C1([H])([H])C([H])([H])[C@](C([H])([H])[H])(C(=C([H])C([H])([H])[C@]([H])([C@@]([H])([C@]2([H])[C@@]([H])(O[H])O[C@@]([H])(C([H])([H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C3([H] )[H])[C@@]34C([H])([H])[H])[C@@]4(C([H])([H])[H])[C@]([H])(O[H])C5([H])[H])[C@@]5([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]

成分:

HBIN013032

OB_score:

10.940319

SymMap_id:

SMIT05888;SMIT19514

TCMID_id:

32110;21668

TCMSP_id:

MOL003882


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE003919 Medicago sativa 苜蓿 To clear heat and cool blood, disinhibit damp and abate jaundice./Febrile diseases with vexation and fullness, jaundice, enteritis, dysentery, edema, urethral stone, hematochezia from hemorrhoids.
TCMBANKHE004017 Dysoxylum hongkongense 香港樫木 To interrupt malaria./Malaria.
TCMBANKHE004267 Achillea millefolium 洋蓍草 To dispel wind, quicken blood, relieve pain, resolve toxin./Wind-damp impediment pain, knocks and falls, amenorrhea due to blood stasis, swelling toxin of welling abscess and sore, bleeding from hemorrhoids.
TCMBANKHE004523 Flos Gossampini 木棉花 Diarrhea, dysentery, hemoptysis, blood ejection, flooding, incised wound and bleeding, sore toxin, eczema.
TCMBANKHE006660 Ramulus Cinmomi 桂枝 To induce perspiration, to warm the channels and stimulate menstrual discharge, to reinforce yang, to relieve palpitation, and to promote the descending of qi./Wind-cold exterior syndrome, cold-damp impediment pain, reversal cold of limbs, amenorrhea and dysmenorrhea, concretion and conglomeration, chest impediment, palpitation, phlegm-rheum, inhibited urination.
TCMBANKHE004838 Radix Sophorae Tonkinensis 山豆根 To remove toxic heat, promote the subsidence of swelling, and soothe the sore throat./Septicemia, ulcer of uterine cervix, chronic cervicitis, bacillary dysentery, enteritis, hydatid moles, chorioblastoma, asthma, chronic bronchitis, acute tonsillitis, laryngitis, accumulated fire toxin, swelling pain in throat, gingiva painful swelling.
TCMBANKHE005272 Astragalus sinicus 紫云英 To clear heat and resolve toxin, dispel wind and brighten eyes, cool blood and stanch bleeding./Pain in throat, wind-phlegm cough, red eyes with gall, clove sore, zoster, scab and lichen, hemorrhoids, gum hemorrhage, bleeding due to external injury, menstrual disorder, vaginal discharge, thrombocytopenic purpura.
TCMBANKHE005444 白鲜皮 To clear heat and dry damp, dispel wind and relieve itch, resolve toxin./1. Inhibiting the growth of pathogenic fungi. 2. Its infusion lowers vaccine-induced fever in rabbits. 3. Dictamnine, one of its active components, increase the myocardial tone of frogs. Dermatitis, psoriasis, icterohepatitis, damp-heat sore and papules, profuse pus, yellow-water sore, damp ulceration on skin, itchy skin, damp-heat jaundice, damp-heat impediment.
TCMBANKHE006031 Bulbus Fritillariae Ussuriensis 平贝母 To remove heat from the lung, relieve cough and resolve phlegm./Dry cough due to lung dryness, dry cough, yin vacuity taxation cough, cough with phlegm and blood.
TCMBANKHE006298 Lycopersicon esculentum ;西红柿 To engender liquid and allay thirst, fortify stomach and disperse food./Thirst, inappetence.
TCMBANKHE006352 Abrus Precatorius L. 相思子 Vomiting, welling abscess, parotitis, scab and lichen, wind-damp bone pain.
TCMBANKHE006696 Pisum sativum 豌豆 To harmonize center and precipitate qi, free milk and disinhibit water, resolve toxin./Cholera cramp, beriberi with edema, diabetes mellitus, vomiting of sour matter, abdominal distention and diarrhea, scant breast milk, swollen welling abscess.
TCMBANKHE007607/YNS-333/YEM-207/XU-39/XU-129 Mirabilis jalapa|Mirabilis jalapa Linn.|Mirabilis jalapa L. 紫茉莉叶|紫茉莉 紫茉莉根|紫茉莉 云南药材标准:第四册|云南民族药物志:第一卷|云南省昆明市盘龙区黑龙潭 淸热利湿,活血消肿。用于乳痈,赤白带下,月经不调;热淋;痈疮肿毒|To clear heat and resolve toxin, dispel wind and percolate damp, quicken blood./Welling abscess, boil, scab sore, lichen, wound. 阿昌族/白族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族/彝族
TCMBANKHE004087/YEM-220 Fructus Quisqualis|Quisqualis indica L. 使君子 使君子 云南民族药物志:第二卷 To kill worms./Ascariasis, oxyuria disease, child gan accumulation. 阿昌族/傣族/德昂族/景颇族/傈僳族/普米族/佤族/瑶族
TCMBANKHE004393/YEM-220 Quisqualis indica|Quisqualis indica L. 使君子叶|使君子 使君子 云南民族药物志:第二卷 To rectify qi and fortify spleen, resolve toxin and kill worms./Child gan accumulation, distention fullness in stomach duct and abdomen, worm accumulation, ulcerating sore and boil. 阿昌族/傣族/德昂族/景颇族/傈僳族/普米族/佤族/瑶族
TCMBANKHE006164/YEM-243 Cannabis sativa|Cannabis sativa L. 麻花|大麻 大麻 云南民族药物志:第二卷 To dispel wind, quicken blood, engender hairs./Numbness in limbs, itchy body, shedding of eyebrow and hair, amenorrhea. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE005716/YEM-243 Semen Canbis;Fructus Canbis;Fructus cannabis|Cannabis sativa L. 火麻仁;麻子仁|大麻 大麻 云南民族药物志:第二卷 To cause Taxation.;Purging by moisterizing/Blood and liquid depletion, intestinal dry and constipation. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE005619/YEM-411 Solanum melongena|Solanum melongena L. 茄子|茄 茄子 云南民族药物志:第二卷 To clear heat and quicken blood, disperse swelling and relieve pain./Intestinal wind bleeding, heat toxin swollen welling abscess. 傣族/德昂族/基诺族/佤族
TCMBANKHE004273/YEM-411 Solanum melongena|Solanum melongena L. 茄叶|茄 茄子 云南民族药物志:第二卷 To dissipate blood and disperse swelling./Blood strangury, blood dysentery, intestinal wind bleeding, swollen welling abscess, frostbite. 傣族/德昂族/基诺族/佤族
TCMBANKHE004643/YEM-590/XU-716 Folium Mori|Morus alba L.|Morus alba 桑叶|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE006699/YEM-696 Cucurbita moschata|Cucurbita moschata(Duch.ex Lam.)Duch.ex Poiret 南瓜 南瓜 云南民族药物志:第四卷 To resolve toxin and disperse swelling./Pulmonary welling abscess, asthma, swollen welling abscess, scalds, poisonous bee stings. 阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/水族/佤族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1